Product image of Levoethin (Ethinylestradiol, Levonorgestrel) supplied by GNH India

Levoethin

Active Ingredient:
Ethinylestradiol, Levonorgestrel
Origin:
EU

Levoethin (Ethinylestradiol, Levonorgestrel)

Ethinylestradiol/Levonorgestrel, the active ingredient in Levoethin, is a combined oral contraceptive presented as a tablet for oral use. It prevents pregnancy and can help regulate menstrual cycles in women of reproductive age.

GNH India supplies Levoethin as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stada Arzneimittel Ag

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Indications & Clinical Uses

  • Levoethin, a combined estrogen‑progestin oral contraceptive, is used for hormonal control of reproductive health.
  • Contraception: Prevents pregnancy by inhibiting ovulation and altering cervical mucus.
  • Menstrual cycle regulation: Provides more predictable bleeding patterns and reduces menstrual irregularities.
  • Hormonal cycle control: Allows scheduled withdrawal bleeding during the placebo phase.

How It Works

  • Ethinylestradiol and levonorgestrel act synergistically to suppress the hypothalamic‑pituitary‑ovarian axis, reducing the secretion of luteinising hormone and follicle‑stimulating hormone, thereby preventing follicular development and ovulation. The progestin component also thickens cervical mucus and induces endometrial changes that diminish the likelihood of implantation.

Side Effects

Levoethin may cause a range of adverse reactions. Common Side Effects:

  • Nausea: Mild to moderate stomach upset.
  • Breast tenderness: Sensitivity or swelling of the breasts.
  • Headache: Transient head pain.
  • Spotting: Light bleeding between periods.

Serious or Rare Side Effects

  • Deep vein thrombosis: Blood clot formation in deep veins.
  • Pulmonary embolism: Clot migration to the lungs.
  • Severe allergic reaction: Anaphylaxis or angioedema requiring immediate medical attention.

Precautions & Warnings

Levoethin requires careful consideration of several health factors before use.

  • Smoking: Avoid smoking, especially if over 35 years old, due to increased thrombotic risk.
  • Cardiovascular disease: Do not use if you have a history of thromboembolic disorders or uncontrolled hypertension.
  • Liver disease: Use with caution in patients with hepatic impairment.
  • Pregnancy: Discontinue immediately if pregnancy is confirmed.
  • Medication adherence: Take the tablet at the same time each day to maintain efficacy.
  • Store at ambient temperature: Keep below 25°C, in the original packaging, and protect from moisture.

Avoid Interactions

Levoethin can interact with other medicines, affecting its effectiveness or safety.

Major Interactions (Avoid)

  • Antiepileptic enzyme inducers (e.g., carbamazepine, phenytoin): Reduce contraceptive efficacy.
  • Rifampin (antibiotic): May lower hormone levels and increase risk of breakthrough bleeding.

Moderate Interactions (Monitor Closely)

  • Antifungal azoles (e.g., ketoconazole): May increase hormone concentrations.
  • St. John’s wort: Can decrease contraceptive effectiveness.
  • Protease inhibitors (e.g., ritonavir): May raise hormone levels and alter side‑effect profile.

Frequently Asked Questions

Levoethin is a combined oral contraceptive containing ethinylestradiol and levonorgestrel. It is prescribed to prevent pregnancy and to help regulate menstrual cycles in women of reproductive age, providing reliable birth control and more predictable bleeding patterns.

The estrogen (ethinylestradiol) and progestin (levonorgestrel) suppress the release of luteinising hormone and follicle‑stimulating hormone, which blocks ovulation. The progestin also thickens cervical mucus and alters the endometrium, creating an environment that reduces the chance of fertilisation and implantation.

The specific dosing regimen is determined by the prescribing clinician. Typically, Levoethin is taken as a daily tablet for a 21‑day active phase followed by a 7‑day placebo phase, but the exact schedule and strength are set by the healthcare professional based on individual needs.

Levoethin is not intended for use during pregnancy; if pregnancy occurs, the product should be discontinued immediately. Limited data exist for breastfeeding, and while some clinicians may allow use after the first postpartum weeks, it should only be taken under medical advice.

To order Levoethin, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Levoethin offers efficacy comparable to other combined estrogen‑progestin pills. Differences lie mainly in the specific hormone doses, which can influence side‑effect profiles such as weight change, mood variation, or risk of breakthrough bleeding. Clinicians choose based on individual patient risk factors and tolerability.

Store Levoethin at ambient temperature, preferably below 25 °C. Keep the tablets in their original packaging, protect them from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.

Levoethin is taken orally as a tablet once daily, preferably at the same time each day. It may be taken with or without food, but consistent timing helps maintain steady hormone levels and maximises contraceptive effectiveness.

The most serious risks include thromboembolic events such as deep‑vein thrombosis and pulmonary embolism, as well as rare but severe allergic reactions like anaphylaxis. Women with a history of clotting disorders, certain cancers, or uncontrolled hypertension should discuss these risks with their clinician.

Levoethin is contraindicated in women who have a history of thromboembolic disease, estrogen‑dependent tumors, uncontrolled hypertension, severe liver disease, or who are smokers over 35 years old. It should also be avoided during pregnancy and in individuals with known hypersensitivity to any component of the product.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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