Product image of Levoethin (Ethinylestradiol, Levonorgestrel) supplied by GNH India

Levoethin

Active Ingredient:
Ethinylestradiol, Levonorgestrel
Origin:
EU

Levoethin (Ethinylestradiol, Levonorgestrel)

Ethinylestradiol and Levonorgestrel, the active ingredients in Levoethin, are a combined oral contraceptive presented as a tablet for oral use. They work together to prevent pregnancy and to help regulate menstrual cycles in women of reproductive age.

GNH India supplies Levoethin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product complies with EU regulatory standards and is manufactured under strict quality‑assured processes, ensuring consistent potency and safety for patients. Levoethin is available in bulk packaging suitable for large‑scale healthcare procurement.

Manufacturer / TM Owner

Stada Arzneimittel Ag

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Indications & Clinical Uses

  • Levoethin is a combined oral contraceptive that acts on the hormonal regulation of the menstrual cycle.
  • Prevention of pregnancy: provides reliable hormonal birth control.
  • Regulation of menstrual cycles: helps achieve predictable periods and reduce irregular bleeding.
  • Management of menstrual symptoms: can lessen dysmenorrhea and premenstrual discomfort.

How It Works

  • Ethinylestradiol (an estrogen) and levonorgestrel (a progestin) bind to estrogen and progesterone receptors, suppressing the hypothalamic‑pituitary release of luteinizing hormone and follicle‑stimulating hormone, thereby inhibiting ovulation. The combination also thickens cervical mucus and induces endometrial changes that reduce the likelihood of fertilization and implantation.

Side Effects

Levoethin may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Nausea
  • Headache
  • Breast tenderness
  • Spotting or irregular bleeding
  • Mood changes
  • Weight gain

Serious or Rare Side Effects

  • Deep vein thrombosis or pulmonary embolism
  • Stroke or myocardial infarction
  • Severe allergic reaction (anaphylaxis)
  • Hepatic adenoma or other serious liver disorders

Precautions & Warnings

Before prescribing Levoethin, clinicians should evaluate individual risk factors and counsel patients on safe use.

  • Cardiovascular assessment: review history of thromboembolic disease or uncontrolled hypertension.
  • Smoking restriction: advise women over 35 not to smoke more than 15 cigarettes per day.
  • Liver function: avoid use in active liver disease.
  • Pregnancy avoidance: ensure patient is not pregnant and uses reliable backup contraception when starting.
  • Drug interactions: check for concomitant enzyme‑inducing medications.
  • Store at below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Levoethin can interact with several medicines that alter hormone metabolism or increase clotting risk.

Major Interactions (Avoid)

  • Rifampin, carbamazepine, phenytoin: potent enzyme inducers that reduce contraceptive efficacy.
  • Ritonavir and other strong CYP3A4 inhibitors: may increase hormone levels and risk of side effects.
  • St. John’s wort: herbal inducer that can diminish contraceptive effect.

Moderate Interactions (Monitor Closely)

  • Ketoconazole and other azole antifungals: may increase hormone concentrations.
  • Certain SSRIs (e.g., fluoxetine): potential for modest interaction.
  • Valproic acid: may affect hormone levels and require monitoring.

Frequently Asked Questions

Levoethin is a combined oral contraceptive containing ethinylestradiol and levonorgestrel. It is prescribed to prevent pregnancy and to help regulate menstrual cycles in women of reproductive age. It may also be used to manage menstrual‑related symptoms under medical supervision.

Ethinylestradiol (an estrogen) and levonorgestrel (a progestin) act on the hypothalamic‑pituitary‑ovarian axis. They suppress the surge of luteinizing hormone and follicle‑stimulating hormone, thereby inhibiting ovulation. Additionally, they thicken cervical mucus and alter the endometrial lining, creating conditions unfavorable for fertilization and implantation.

The dosing regimen for Levoethin is determined by the prescribing healthcare professional. Typically, the product is taken as a daily tablet in a 21‑day active‑pill sequence followed by a hormone‑free interval, but the exact schedule and any missed‑dose instructions must be provided by the prescriber.

Levoethin is classified as pregnancy category X, indicating it must not be used during pregnancy because it can cause fetal harm. Women who are breastfeeding should consult their healthcare provider, as hormonal contraceptives may affect milk production and infant exposure.

To place an order, submit an enquiry on the Levoethin product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levoethin contains the standard dose combination of ethinylestradiol and levonorgestrel, which is widely used and well‑studied. Compared with newer formulations that may use different progestins or lower estrogen doses, Levoethin offers a familiar efficacy and side‑effect profile, making it a reliable option for many patients.

Store Levoethin at below 25 °C in its original packaging, protecting it from moisture and direct sunlight. Do not keep the tablets in bathrooms or near heat sources. Proper storage maintains tablet potency throughout its shelf life.

Levoethin is taken orally, usually once each day at the same time, with or without food. The tablets are typically arranged in a blister pack containing 21 active pills followed by a 7‑day hormone‑free interval, during which withdrawal bleeding occurs. Follow the prescriber’s instructions for missed doses.

The most serious risks include venous thromboembolism, pulmonary embolism, stroke, myocardial infarction, and severe allergic reactions. These events are rare but can be life‑threatening, especially in women with pre‑existing cardiovascular risk factors, smoking habits, or a history of clotting disorders.

Levoethin is contraindicated in women who are pregnant, have a history of thromboembolic disease, uncontrolled hypertension, known or suspected estrogen‑dependent tumors, active liver disease, or who smoke heavily (more than 15 cigarettes per day) and are over 35 years old. Consultation with a healthcare professional is essential before starting therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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