Product image of Levofloxacin Olikla (Levofloxacin Hemihydrate) supplied by GNH India

Levofloxacin Olikla

Active Ingredient:
Levofloxacin Hemihydrate
Origin:
EU

Levofloxacin Olikla (Levofloxacin Hemihydrate)

Levofloxacin, the active ingredient in Levofloxacin Olikla, is a fluoroquinolone antibiotic presented as a sterile ophthalmic solution for ocular use. It treats bacterial eye infections such as conjunctivitis, keratitis and post‑surgical infections in both adult and pediatric patients as prescribed by a qualified eye‑care professional.

GNH India supplies Levofloxacin Olikla as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation to support global distribution, ensuring product integrity and traceability throughout the supply chain.

Manufacturer / TM Owner

Olikla S.R.O.

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Indications & Clinical Uses

Levofloxacin Olikla is used in ophthalmology to treat bacterial infections of the eye and surrounding tissues.

  • Bacterial conjunctivitis: reduces bacterial load, alleviates redness and discharge, promoting rapid symptom resolution.
  • Corneal ulcer: eradicates causative organisms, facilitating corneal healing and preventing scarring.
  • Post‑operative ocular infection: prevents bacterial colonisation after eye surgery, supporting uncomplicated recovery.
  • Keratitis: eliminates pathogens causing corneal inflammation, aiding visual recovery.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication and transcription. By binding to these enzymes, it prevents the supercoiling and separation of bacterial DNA, leading to halted bacterial cell division and eventual cell death. The drug exhibits concentration‑dependent bactericidal activity against a broad spectrum of Gram‑negative and Gram‑positive ocular pathogens.

Side Effects

Common Side Effects

  • Eye irritation or burning sensation
  • Redness of the conjunctiva
  • Foreign body sensation
  • Increased tearing
  • Blurred vision
  • Mild headache

Serious or Rare Side Effects

  • Severe allergic reaction (angioedema, anaphylaxis)
  • Corneal ulcer worsening
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Significant ocular inflammation
  • Systemic hypersensitivity (rash, fever)
  • Vision loss due to retinal toxicity

Precautions & Warnings

Levofloxacin Olikla should be used with caution in the following situations:

  • Allergy assessment: avoid if known hypersensitivity to fluoroquinolones.
  • Contact lens wear: discontinue lens use during treatment to reduce irritation.
  • Pregnancy and lactation: safety unknown; prescribe only if benefits outweigh potential risks.
  • Systemic absorption: monitor patients with tendon disorders for signs of tendonitis.
  • Drug interactions: avoid concurrent use of other ophthalmic antibiotics unless directed.
  • Store at below 25°C: keep in the original container, protect from light and moisture.

Avoid Interactions

Levofloxacin Olikla may interact with other ophthalmic or systemic agents.

Major Interactions (Avoid)

  • Systemic fluoroquinolones: increased risk of additive toxicity.
  • Corticosteroid eye drops: may mask infection signs and delay healing.

Moderate Interactions (Monitor Closely)

  • Anticholinergic eye drops: possible alteration of pupil response.
  • Non‑steroidal anti‑inflammatory eye drops: may delay corneal epithelial repair.
  • Herbal supplements containing quinine: potential pharmacodynamic interaction.

Frequently Asked Questions

Levofloxacin Olikla is an ophthalmic solution containing the fluoroquinolone antibiotic levofloxacin. It is prescribed to treat bacterial eye infections such as conjunctivitis, corneal ulcers, and post‑operative infections, helping to eliminate the causative bacteria and restore ocular health.

Levofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes that are essential for DNA replication and transcription. By blocking these enzymes, the drug prevents bacterial cell division, leading to rapid bacterial death and clearance of the infection from ocular tissues.

The dosing regimen for Levofloxacin Olikla is determined by the prescribing eye‑care professional based on the specific infection, severity, and patient factors. Only a qualified clinician should set the frequency and duration of treatment.

Safety data for levofloxacin use in pregnancy and lactation are limited, and the product is classified as having an unknown pregnancy category. It should be used only if the potential benefit justifies the potential risk to the fetus or infant, and under medical supervision.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Levofloxacin belongs to the fluoroquinolone class, offering broad‑spectrum activity against Gram‑negative and Gram‑positive ocular pathogens. Compared with older agents such as chloramphenicol or macrolides, levofloxacin often provides faster bacterial eradication and a lower risk of resistance, though individual choice depends on susceptibility patterns and clinician preference.

Levofloxacin Olikla should be stored at temperatures below 25 °C, in its original packaging, protected from light and moisture. Do not freeze the solution, and keep the container tightly closed when not in use to maintain sterility.

The solution is applied directly to the affected eye(s) as eye drops. The prescriber will advise the number of drops per dose and the dosing interval, typically ranging from one to several times daily, depending on the infection severity.

Serious risks include severe allergic reactions such as anaphylaxis, worsening of corneal ulcers, and rare systemic hypersensitivity reactions like Stevens‑Johnson syndrome. Patients should be instructed to seek immediate medical attention if they experience signs of a severe reaction.

Individuals with a known hypersensitivity to levofloxacin, other fluoroquinolones, or any component of the formulation should avoid using the product. Caution is also advised for patients with tendon disorders, uncontrolled epilepsy, or those taking interacting ophthalmic medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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