Levofloxacin/Rafarm (Pf) (Levofloxacin Hemihydrate)

Levofloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. By inhibiting these targets, the drug prevents bacterial cell division, leading to rapid bactericidal activity against a broad range of Gram‑positive and Gram‑negative ocular pathogens.

The appropriate dosing regimen for Levofloxacin/Rafarm is determined by the prescribing clinician based on the type and severity of the ocular infection, patient age, and any relevant ocular comorbidities. No fixed dose is provided here; the prescriber sets the exact regimen.

Safety data for levofloxacin in pregnancy and lactation are limited, and the product is classified as having an unknown pregnancy category. It should be used only if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by a qualified health professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. The sales team then replies with pricing, availability, shipping details and any required import documentation.

Levofloxacin belongs to the fluoroquinolone class and offers broad‑spectrum coverage, including many Gram‑positive and Gram‑negative organisms. Compared with older agents such as ciprofloxacin, levofloxacin often provides higher potency and better ocular penetration, while newer agents like moxifloxacin have similar spectra but may differ in dosing frequency and resistance patterns.

Store the ophthalmic solution at room temperature, preferably below 25 °C. Keep the container tightly closed, protect it from direct light and moisture, and retain it in the original packaging until use. Do not freeze the product, and discard any solution that appears discolored or contains particles.

Levofloxacin/Rafarm is applied as eye drops. The prescribed number of drops is placed into the conjunctival sac of the affected eye(s) at the intervals directed by the prescriber, typically using a clean fingertip to pull down the lower eyelid and avoid contamination of the dropper tip.

Serious adverse reactions, although rare, include corneal ulceration or worsening of existing lesions, allergic keratitis, Stevens‑Johnson syndrome, and systemic anaphylaxis. Patients should seek immediate medical attention if they experience severe eye pain, rapid vision loss, extensive redness, or signs of an allergic reaction such as swelling and difficulty breathing.

Levofloxacin/Rafarm should be avoided in individuals with a known hypersensitivity to levofloxacin, other fluoroquinolones, or any component of the formulation. It is also contraindicated in patients with a history of tendon disorders related to fluoroquinolone use and should be used with caution in those with severe corneal epithelial defects.