Product image of Levofloxacin Reiwa Healthcare (Levofloxacin) supplied by GNH India

Levofloxacin Reiwa Healthcare

Active Ingredient:
Levofloxacin
Origin:
EU

Levofloxacin Reiwa Healthcare (Levofloxacin)

Levofloxacin, the active ingredient in Levofloxacin Reiwa Healthcare, is a fluoroquinolone antibiotic presented as an intravenous formulation for IV use. It treats a variety of serious bacterial infections, including community‑acquired pneumonia, complicated urinary tract infections, skin and soft‑tissue infections, intra‑abdominal infections, and prostatitis in adult patients.

GNH India supplies Levofloxacin Reiwa Healthcare as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reiwa Healthcare S.L

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Indications & Clinical Uses

Levofloxacin is a fluoroquinolone antibiotic used to treat a range of bacterial infections.

  • Community‑acquired pneumonia: eradicates the causative bacteria and improves respiratory function.
  • Complicated urinary tract infections: eliminates pathogenic organisms in the urinary system.
  • Skin and soft‑tissue infections: resolves bacterial skin infections and promotes healing.
  • Intra‑abdominal infections: targets mixed aerobic and anaerobic bacteria within the abdominal cavity.
  • Prostatitis: reduces bacterial load in the prostate and alleviates symptoms.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. By binding to these enzymes, it prevents the supercoiling and separation of DNA strands, leading to bacterial cell death. This bactericidal action is effective against a broad spectrum of Gram‑positive and Gram‑negative organisms, including many resistant strains.

Side Effects

Levofloxacin may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Nausea or vomiting: gastrointestinal upset occurring in many patients.
  • Diarrhea: loose stools that may be self‑limiting.
  • Headache: mild to moderate cranial discomfort.
  • Rash: skin erythema or mild itching.

Serious or Rare Side Effects

  • Tendon rupture: sudden tendon pain or rupture, especially in the Achilles.
  • QT interval prolongation: cardiac rhythm disturbances that may lead to arrhythmia.
  • Severe hypersensitivity: anaphylaxis or Stevens‑Johnson syndrome requiring immediate medical attention.

Precautions & Warnings

Before initiating therapy, clinicians should consider several safety measures.

  • Assess renal function: adjust dosing in patients with impaired clearance.
  • Review cardiac history: avoid use in individuals with known QT prolongation.
  • Monitor for tendon pain: discontinue if sudden tendon discomfort occurs.
  • Evaluate for CNS disorders: caution in patients with seizures or psychiatric conditions.
  • Store at ambient temperature: keep in original packaging, protect from moisture and light.

Avoid Interactions

Levofloxacin can interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Antacids containing aluminum or magnesium: reduce levofloxacin absorption; separate administration by at least 2 hours.
  • Warfarin: may increase anticoagulant effect; monitor INR closely.

Moderate Interactions (Monitor Closely)

  • NSAIDs: heightened risk of central nervous system stimulation; observe for tremor or seizures.
  • Corticosteroids: increased chance of tendon rupture; advise patients to report tendon pain.
  • Diabetic agents: potential for dysglycemia; monitor blood glucose levels regularly.

Frequently Asked Questions

Levofloxacin Reiwa Healthcare is indicated for serious bacterial infections such as community‑acquired pneumonia, complicated urinary tract infections, skin and soft‑tissue infections, intra‑abdominal infections, and prostatitis. It is prescribed when a broad‑spectrum fluoroquinolone is appropriate for the identified or suspected pathogen.

Levofloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. By preventing DNA supercoiling and strand separation, it halts bacterial cell division and leads to bacterial death, providing a bactericidal effect against a wide range of Gram‑positive and Gram‑negative organisms.

The dosage of Levofloxacin Reiwa Healthcare is determined by the prescribing clinician based on the infection type, severity, patient weight, renal function, and local guidelines. The prescriber sets the exact dose, frequency, and duration of therapy.

Safety of levofloxacin in pregnancy or lactation has not been definitively established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and necessary import documentation.

Levofloxacin offers broad‑spectrum coverage, including many resistant strains, and can be administered intravenously for severe infections. Compared with beta‑lactams, it may have a faster bactericidal effect but carries specific risks such as tendon toxicity and QT prolongation, requiring careful patient selection.

Levofloxacin Reiwa Healthcare should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original container, protect it from moisture and direct light, and avoid exposure to extreme temperatures to maintain stability.

Levofloxacin Reiwa Healthcare is given by intravenous infusion under the supervision of a healthcare professional. The infusion rate and duration are set by the prescriber and nursing staff, following aseptic technique and appropriate monitoring during administration.

Serious risks include tendon rupture (especially Achilles), QT interval prolongation leading to arrhythmias, severe hypersensitivity reactions such as anaphylaxis or Stevens‑Johnson syndrome, and potential central nervous system effects like seizures. Patients should be educated to report any sudden tendon pain, palpitations, or skin reactions immediately.

Levofloxacin should be avoided in patients with known hypersensitivity to fluoroquinolones, a history of tendon disorders related to fluoroquinolone use, significant QT prolongation, or those receiving concomitant medications that markedly increase the risk of tendon rupture or cardiac arrhythmias. Clinical judgment is essential.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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