Product image of Levofloxacin Teva Uk (Levofloxacin) supplied by GNH India

Levofloxacin Teva Uk

Active Ingredient:
Levofloxacin
Origin:
EU

Levofloxacin Teva Uk (Levofloxacin)

Levofloxacin, the active ingredient in Levofloxacin Teva Uk, is a fluoroquinolone antibiotic presented as an oral tablet for oral use. It treats a range of bacterial infections in adults and children as prescribed.

GNH India supplies Levofloxacin Teva Uk as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Uk Limited

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Indications & Clinical Uses

Levofloxacin is a fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria.

  • Community‑acquired pneumonia: eradicates the causative bacteria and improves respiratory function.
  • Acute bacterial sinusitis: reduces sinus inflammation and clears pathogenic organisms.
  • Acute exacerbation of chronic bronchitis: controls bacterial flare‑ups and eases coughing.
  • Urinary tract infection: eliminates uropathogens and relieves urinary symptoms.
  • Skin and soft‑tissue infections: combats bacterial invasion of skin layers and promotes healing.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication and transcription. By binding to these enzymes, it prevents the unwinding and resealing of DNA strands, leading to bacterial cell death and suppression of infection growth.

Side Effects

Levofloxacin may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Diarrhea: loose stools, sometimes watery.
  • Headache: transient cranial discomfort.
  • Dizziness: sensation of light‑headedness.
  • Insomnia: difficulty falling or staying asleep.
  • Abdominal pain: cramping or discomfort in the stomach area.

Serious or Rare Side Effects

  • Tendon rupture: sudden pain and loss of function, especially in the Achilles tendon.
  • QT interval prolongation: potential cardiac arrhythmias.
  • Severe allergic reactions: rash, swelling, or anaphylaxis.
  • Clostridioides difficile infection: severe colitis with watery diarrhea.
  • Peripheral neuropathy: tingling or numbness in extremities.
  • Stevens‑Johnson syndrome: serious skin and mucous membrane disorder.

Precautions & Warnings

Before prescribing Levofloxacin, clinicians should consider several safety factors.

  • Assess renal function: adjust dose in patients with impaired clearance.
  • Avoid in patients with known hypersensitivity to fluoroquinolones: discontinue if allergic reaction occurs.
  • Monitor for tendon pain: discontinue therapy at first sign of tendon inflammation.
  • Use with caution in patients with QT prolongation: avoid concomitant QT‑prolonging drugs.
  • Separate administration from antacids containing aluminum or magnesium: give at least 2 hours apart.
  • Store at below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Levofloxacin can interact with several medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Antacids containing aluminum or magnesium: reduce levofloxacin absorption.
  • Warfarin: may increase anticoagulant effect and bleeding risk.
  • Theophylline: can raise theophylline plasma levels, leading to toxicity.

Moderate Interactions (Monitor Closely)

  • NSAIDs: may increase risk of central nervous system stimulation.
  • Insulin or oral hypoglycemics: can cause hypoglycemia; monitor blood glucose closely.

Frequently Asked Questions

Levofloxacin Teva Uk is prescribed for a variety of bacterial infections, including community‑acquired pneumonia, acute bacterial sinusitis, acute exacerbations of chronic bronchitis, urinary tract infections, and skin or soft‑tissue infections. It is effective against susceptible Gram‑negative and Gram‑positive organisms when used as directed by a healthcare professional.

Levofloxacin works by binding to bacterial DNA gyrase and topoisomerase IV, enzymes that are essential for DNA replication and transcription. Inhibiting these enzymes prevents the bacteria from unwinding and resealing their DNA, leading to bacterial cell death and resolution of the infection.

The dosage of Levofloxacin Teva Uk is determined by the prescribing clinician based on the type and severity of the infection, patient age, renal function, and other clinical factors. Patients should follow the exact dosing instructions provided by their healthcare provider.

The safety of levofloxacin in pregnancy and lactation has not been definitively established. It is generally avoided unless the potential benefit outweighs the potential risk to the fetus or infant. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss alternatives with their healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials. After verification, the team provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Levofloxacin is a third‑generation fluoroquinolone offering broad‑spectrum activity against many Gram‑negative and Gram‑positive bacteria. Compared with older fluoroquinolones, it has improved potency, once‑daily dosing options, and a more favorable safety profile for certain adverse events, though class‑related risks such as tendon injury remain.

Levofloxacin Teva Uk should be stored at temperatures below 25 °C, in its original packaging to protect from moisture and light. Keep the product out of reach of children and avoid storing in humid environments such as bathrooms.

Levofloxacin Teva Uk is taken orally, usually as a tablet, with or without food as directed by the prescriber. If tablets are taken with antacids or supplements containing calcium, iron, magnesium, or aluminum, they should be spaced at least two hours apart to ensure proper absorption.

Serious risks include tendon rupture or inflammation, especially in the Achilles tendon, QT interval prolongation that can lead to cardiac arrhythmias, severe allergic reactions such as anaphylaxis, and Clostridioides difficile‑associated colitis. Patients should seek immediate medical attention if they experience sudden tendon pain, palpitations, or severe skin reactions.

Levofloxacin should not be used by individuals with a known hypersensitivity to levofloxacin, other fluoroquinolones, or any of the product’s excipients. It is also contraindicated in patients with a history of tendon disorders related to fluoroquinolone use, and it should be avoided in those with significant QT prolongation without careful monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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