Product image of Levofloxacin Viatris (Levofloxacin) supplied by GNH India

Levofloxacin Viatris

Active Ingredient:
Levofloxacin
Origin:
EU

Levofloxacin Viatris (Levofloxacin)

Levofloxacin, the active ingredient in Levofloxacin Viatris, is a fluoroquinolone antibiotic presented as an oral tablet for systemic use. It treats a range of bacterial infections in adults and children when prescribed by a qualified health professional.

GNH India supplies Levofloxacin Viatris as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Viatris Limited

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Indications & Clinical Uses

  • Levofloxacin is a broad‑spectrum fluoroquinolone used to treat infections caused by susceptible bacteria.
  • Community‑acquired pneumonia: eradicates the causative pathogens and improves respiratory function.
  • Acute bacterial sinusitis: reduces sinus inflammation and clears infection.
  • Acute exacerbations of chronic bronchitis: shortens symptom duration and prevents complications.
  • Uncomplicated urinary tract infections: eliminates uropathogens and resolves dysuria.
  • Skin and soft‑tissue infections: controls bacterial spread and promotes wound healing.
  • Intra‑abdominal infections: targets mixed flora and supports recovery after surgery.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. By binding to these enzymes, it prevents the supercoiling and separation of DNA strands, leading to bacterial cell death and cessation of infection growth.

Side Effects

Levofloxacin may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Nausea
  • Diarrhea
  • Headache
  • Dizziness
  • Abdominal pain
  • Insomnia

Serious or Rare Side Effects

  • Tendon rupture or tendinitis
  • QT interval prolongation and cardiac arrhythmias
  • Clostridioides difficile‑associated colitis
  • Severe allergic reactions (e.g., Stevens‑Johnson syndrome)
  • Peripheral neuropathy
  • Hepatic dysfunction or jaundice

Precautions & Warnings

  • Levofloxacin requires careful consideration of patient‑specific factors and proper handling.
  • Pregnancy: contraindicated because of potential fetal harm.
  • Renal impairment: dose adjustment may be necessary to avoid accumulation.
  • History of tendon disorders: avoid use due to risk of tendon rupture.
  • Concurrent antacids or multivalent cations: may reduce drug absorption.
  • Known hypersensitivity to fluoroquinolones: do not administer.
  • Store at below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Levofloxacin can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Warfarin: increased anticoagulant effect, risk of bleeding.
  • Theophylline: elevated plasma concentrations, possible toxicity.
  • Other QT‑prolonging agents (e.g., ciprofloxacin, certain antiarrhythmics): additive cardiac risk.
  • Cyclosporine: increased cyclosporine levels, nephrotoxicity.
  • NSAIDs (high‑dose): heightened CNS stimulation and seizure risk.

Moderate Interactions (Monitor Closely)

  • Antacids containing aluminum or magnesium: reduce levofloxacin absorption.
  • Iron or zinc supplements: may lower bioavailability.
  • Diabetes medications (insulin, sulfonylureas): potential alteration of glucose control.
  • Corticosteroids: increased risk of tendon injury.

Frequently Asked Questions

Levofloxacin Viatris is indicated for a variety of bacterial infections, including community‑acquired pneumonia, acute bacterial sinusitis, exacerbations of chronic bronchitis, uncomplicated and complicated urinary tract infections, skin and soft‑tissue infections, and intra‑abdominal infections caused by susceptible organisms.

Levofloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. This inhibition prevents bacterial cells from copying their genetic material, leading to cell death and resolution of the infection.

The prescribed dose of levofloxacin is determined by the treating clinician based on the specific infection, patient age, renal function, and other clinical factors. Only a qualified health professional should set the dosing regimen.

Levofloxacin is contraindicated in pregnancy because it may cause fetal harm. It is also not recommended for breastfeeding mothers, as the drug can be excreted in breast milk and affect the infant.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levofloxacin is a third‑generation fluoroquinolone with a broad spectrum of activity and once‑daily dosing for many indications, offering convenience over some older agents. Its safety profile is similar to other fluoroquinolones, but clinicians consider individual patient risk factors when selecting the most appropriate drug.

Levofloxacin tablets should be stored at temperatures below 25 °C, in the original packaging, and protected from moisture and direct sunlight to maintain potency throughout the shelf life.

Levofloxacin Viatris is taken orally, usually with a full glass of water. It can be taken with or without food, but patients should avoid simultaneous intake of antacids or mineral supplements that may interfere with absorption.

Serious risks include tendon rupture or tendinitis, especially in older adults; QT interval prolongation leading to cardiac arrhythmias; severe hypersensitivity reactions such as Stevens‑Johnson syndrome; and Clostridioides difficile‑associated colitis. Patients should be monitored for these events.

Levofloxacin should not be used by individuals with known hypersensitivity to fluoroquinolones, pregnant women, patients with a history of tendon disorders, or those taking medications that significantly prolong the QT interval without careful monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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