Product image of Levofloxacina Aurobindo (Levofloxacin) supplied by GNH India

Levofloxacina Aurobindo

Active Ingredient:
Levofloxacin
Origin:
EU

Levofloxacina Aurobindo (Levofloxacin)

Levofloxacin, the active ingredient in Levofloxacina Aurobindo, is a fluoroquinolone antibiotic presented as an oral dosage form for systemic use. It treats a range of bacterial infections in adults and is prescribed by qualified healthcare professionals.

GNH India supplies Levofloxacina Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aurobindo Pharma (Italia) S.R.L.

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Indications & Clinical Uses

Levofloxacin is a fluoroquinolone antibiotic used to treat bacterial infections in various organ systems.

  • Urinary tract infections: effective in eradicating susceptible uropathogens and relieving urinary symptoms.
  • Respiratory tract infections: clears common bacterial pathogens causing bronchitis and pneumonia.
  • Skin and soft tissue infections: resolves cellulitis and wound infections caused by susceptible bacteria.
  • Prostatitis: reduces bacterial load in chronic bacterial prostatitis.
  • Gonorrhea: treats uncomplicated Neisseria gonorrhoeae infections.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. By binding to these enzymes, it prevents the supercoiling and separation of DNA strands, leading to bacterial cell death and eradication of the infection.

Side Effects

Levofloxacin may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Nausea
  • Diarrhea
  • Headache
  • Dizziness

Serious or Rare Side Effects

  • Tendon rupture or inflammation
  • QT interval prolongation leading to cardiac arrhythmia
  • Severe allergic reactions such as anaphylaxis
  • Clostridioides difficile‑associated colitis

Precautions & Warnings

Before prescribing levofloxacin, clinicians should consider several safety measures.

  • Assess renal function: adjust dose in patients with impaired clearance.
  • Avoid use in patients with known hypersensitivity to fluoroquinolones.
  • Monitor for tendon pain: discontinue if symptoms appear.
  • Use with caution in patients with cardiac arrhythmias: QT prolongation risk.
  • Store at below 25°C: keep in the original pack, protect from moisture and light.

Avoid Interactions

Levofloxacin can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Antacids containing aluminum or magnesium: reduce levofloxacin absorption.
  • Warfarin: may increase anticoagulant effect and bleeding risk.
  • Co‑administration with other fluoroquinolones: additive toxicity.
  • Cyclosporine: increased serum levels of cyclosporine.

Moderate Interactions (Monitor Closely)

  • Theophylline: may raise plasma concentrations, causing toxicity.
  • NSAIDs: may increase risk of central nervous system stimulation.
  • Glucocorticoids: may elevate risk of tendon rupture.

Frequently Asked Questions

Levofloxacina Aurobindo contains levofloxacin, a fluoroquinolone antibiotic indicated for urinary tract infections, respiratory tract infections such as bronchitis and pneumonia, skin and soft‑tissue infections, chronic bacterial prostatitis, and uncomplicated gonorrhea. It is prescribed when the causative bacteria are susceptible to levofloxacin.

Levofloxacin inhibits two essential bacterial enzymes: DNA gyrase and topoisomerase IV. By binding to these enzymes, it blocks DNA supercoiling and strand separation, which are required for DNA replication and transcription. This disruption leads to bacterial cell death and eradication of the infection.

The dosage of Levofloxacina Aurobindo is determined by the prescribing clinician based on the specific infection, patient age, renal function, and other clinical factors. Only a qualified healthcare professional can set the appropriate dose and treatment duration.

Safety data for levofloxacin in pregnancy and lactation are limited. It is generally avoided unless the potential benefit outweighs the risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives with their healthcare provider.

To request Levofloxacina Aurobindo, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Levofloxacin offers broad‑spectrum activity against many Gram‑negative and Gram‑positive bacteria and has excellent oral bioavailability, allowing convenient oral therapy. Compared with older agents such as ciprofloxacin, it often requires once‑daily dosing and may have a more favorable side‑effect profile, but clinicians must consider resistance patterns and safety warnings.

Levofloxacina Aurobindo should be stored at temperatures below 25 °C, in its original packaging, protected from moisture and direct sunlight. Keeping the product in a dry, cool place helps maintain its potency throughout its shelf life.

Levofloxacina Aurobindo is administered orally, typically as a tablet or oral suspension, depending on the marketed form. It should be taken with a full glass of water, and patients are advised not to take it simultaneously with antacids containing aluminum or magnesium, which can impair absorption.

Serious adverse events linked to levofloxacin include tendon rupture or inflammation, QT interval prolongation that can cause cardiac arrhythmias, severe allergic reactions such as anaphylaxis, and Clostridioides difficile‑associated colitis. Patients should be instructed to report any sudden tendon pain, palpitations, or severe rash immediately.

Levofloxacina Aurobindo should be avoided in individuals with a known hypersensitivity to levofloxacin or any fluoroquinolone, patients with a history of tendon disorders related to fluoroquinolone use, and those with certain cardiac conditions that predispose to QT prolongation. Clinicians must evaluate each patient’s medical history before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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