Product image of Levofloxacina Aurobindo (Levofloxacin) supplied by GNH India

Levofloxacina Aurobindo

Active Ingredient:
Levofloxacin
Origin:
EU

Levofloxacina Aurobindo (Levofloxacin)

Levofloxacin, the active ingredient in Levofloxacina Aurobindo, is a fluoroquinolone presented as an oral dosage form for systemic use. It treats a range of bacterial infections, including urinary, respiratory, skin and soft‑tissue infections, and prostatitis, in adult patients when prescribed by a qualified clinician.

GNH India supplies Levofloxacina Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Generis Farmacêutica, S.A.

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Indications & Clinical Uses

Levofloxacina Aurobindo is a fluoroquinolone antibiotic indicated for several bacterial infection categories.

  • Urinary tract infection: effective against susceptible organisms causing uncomplicated and complicated UTIs.
  • Respiratory tract infection: treats community‑acquired pneumonia and acute exacerbations of chronic bronchitis.
  • Skin and soft tissue infection: resolves infections such as cellulitis and wound infections.
  • Prostatitis: eradicates bacterial pathogens in chronic bacterial prostatitis.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. By stabilizing the enzyme–DNA complex, it prevents the resealing of DNA strands, leading to bacterial cell death and a bactericidal effect against a broad spectrum of Gram‑negative and Gram‑positive organisms.

Side Effects

Levofloxacina Aurobindo may cause adverse reactions that vary in frequency and severity.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Diarrhea: loose stools, occasionally watery.
  • Headache: transient cranial discomfort.
  • Dizziness: sensation of light‑headedness.

Serious or Rare Side Effects

  • Tendon rupture: risk of Achilles or other tendon tears, especially in older adults.
  • QT interval prolongation: may precipitate cardiac arrhythmias.
  • Severe allergic reaction: includes anaphylaxis, angioedema, or Stevens‑Johnson syndrome.

Precautions & Warnings

Levofloxacina Aurobindo requires careful consideration of patient‑specific factors before use.

  • Renal function: dose adjustment may be needed in patients with impaired kidney function.
  • Age: elderly patients have an increased risk of tendon injury and should be monitored closely.
  • Concomitant corticosteroids: avoid combined use due to heightened tendon rupture risk.
  • Cardiac history: patients with known QT prolongation should have ECG monitoring.
  • Pregnancy and lactation: safety not established; avoid unless the benefit outweighs the risk.
  • Store at room temperature below 25°C: keep in the original container, protect from moisture and light.

Avoid Interactions

Levofloxacina Aurobindo can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Antacids containing aluminum or magnesium: markedly reduce levofloxacin absorption.
  • Other fluoroquinolones (e.g., ciprofloxacin): increase risk of QT prolongation and tendon toxicity.
  • Warfarin: may potentiate anticoagulant effect, increasing bleeding risk.

Moderate Interactions (Monitor Closely)

  • Theophylline: levofloxacin can raise serum theophylline levels, requiring dose adjustment.
  • NSAIDs: concurrent use may increase central nervous system stimulation.
  • Diabetes medications (insulin, sulfonylureas): may cause dysglycemia; monitor blood glucose.

Frequently Asked Questions

Levofloxacina Aurobindo is a prescription‑only fluoroquinolone antibiotic indicated for treating bacterial infections such as urinary tract infections, community‑acquired respiratory infections, skin and soft‑tissue infections, and chronic bacterial prostatitis when the causative organisms are susceptible.

Levofloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. This inhibition prevents the resealing of DNA strands, leading to bacterial cell death and a broad‑spectrum bactericidal effect.

The specific dose and treatment duration of Levofloxacina Aurobindo are determined by the prescribing clinician based on the infection type, severity, patient age, renal function, and other clinical factors. No standard dosing regimen is provided here.

Safety data for levofloxacin in pregnancy and lactation are limited. It is generally avoided unless the potential benefit justifies the potential risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Compared with older fluoroquinolones, levofloxacin offers once‑daily dosing and a broader spectrum against Gram‑negative pathogens. Relative to beta‑lactams, it provides rapid bactericidal activity but carries class‑specific risks such as tendon injury and QT prolongation, which must be weighed against clinical benefits.

Store the product at room temperature below 25 °C in its original packaging. Protect it from moisture, excessive heat, and direct sunlight. Keep the container tightly closed and out of reach of children.

Levofloxacina Aurobindo is administered orally. The tablet should be swallowed whole with a full glass of water. It may be taken with or without food, but antacids containing aluminum, magnesium, or calcium should be spaced at least two hours apart to avoid reduced absorption.

Serious adverse events include tendon rupture (especially in older adults or those on corticosteroids), QT interval prolongation leading to arrhythmias, severe hypersensitivity reactions such as anaphylaxis or Stevens‑Johnson syndrome, and Clostridioides difficile‑associated colitis. Patients should seek immediate medical attention if they experience sudden joint pain, palpitations, or severe skin reactions.

Levofloxacina Aurobindo is contraindicated in individuals with a known hypersensitivity to levofloxacin, other fluoroquinolones, or any component of the formulation. It should also be avoided in patients with a history of tendon disorders related to fluoroquinolone use, those with uncontrolled QT prolongation, and generally in pregnancy or breastfeeding unless no safer alternative exists.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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