Product image of Levofloxacina Aurovitas (Levofloxacin) supplied by GNH India

Levofloxacina Aurovitas

Active Ingredient:
Levofloxacin
Origin:
EU

Levofloxacina Aurovitas (Levofloxacin)

Levofloxacin, the active ingredient in Levofloxacina Aurovitas, is a fluoroquinolone antibiotic presented as an intravenous solution for intravenous administration. It is used to treat a range of susceptible bacterial infections in hospitalized patients, including respiratory, urinary and skin‑soft‑tissue infections.

GNH India supplies Levofloxacina Aurovitas as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide. The product meets EU quality standards and is manufactured under strict GMP conditions.

Manufacturer / TM Owner

Eugia Pharma (Malta) Ltd

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Indications & Clinical Uses

Levofloxacin is a fluoroquinolone antibiotic indicated for the treatment of infections caused by susceptible bacteria.

  • Community‑Acquired Pneumonia: rapid bacterial eradication leading to clinical recovery.
  • Complicated Urinary Tract Infection: effective clearance of uropathogens.
  • Skin and Soft Tissue Infection: reduction of bacterial load and symptom resolution.
  • Intra‑Abdominal Infection: control of mixed Gram‑negative and Gram‑positive organisms.
  • Bacterial Prostatitis: eradication of causative pathogens with improved urinary symptoms.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. By stabilizing the DNA‑enzyme complex, it prevents the resealing of DNA strands, leading to bacterial cell death. This bactericidal action is effective against a broad spectrum of Gram‑negative and Gram‑positive organisms.

Side Effects

Levofloxacin may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Diarrhea: loose stools, sometimes watery.
  • Headache: transient cranial discomfort.
  • Dizziness: sensation of light‑headedness.
  • Rash: mild skin erythema.
  • Elevated liver enzymes: transient increase in hepatic markers.

Serious or Rare Side Effects

  • Tendon rupture: especially Achilles tendon, may occur without warning.
  • QT interval prolongation: risk of cardiac arrhythmias.
  • Clostridioides difficile infection: severe colitis.
  • Severe hypersensitivity: including Stevens‑Johnson syndrome.
  • Anaphylaxis: acute, life‑threatening allergic reaction.
  • Peripheral neuropathy: numbness or tingling in extremities.

Precautions & Warnings

Levofloxacin should be used with caution in specific clinical situations.

  • Renal function: dose adjustment may be required in patients with impaired clearance.
  • History of tendon disorders: avoid use in individuals with prior tendon injury.
  • QT prolongation risk: monitor ECG in patients with cardiac arrhythmias.
  • Concomitant NSAIDs: increased risk of central nervous system effects.
  • Pregnancy and lactation: prescribe only if benefits outweigh potential risks.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Levofloxacin can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Antacids containing aluminum or magnesium: reduce levofloxacin absorption.
  • Warfarin: may increase anticoagulant effect and bleeding risk.
  • Cyclosporine: heightened risk of nephrotoxicity.

Moderate Interactions (Monitor Closely)

  • Theophylline: levofloxacin may raise serum theophylline levels.
  • Corticosteroids: combined use increases tendon rupture risk.
  • Diabetes medications: possible alteration of glucose control.

Frequently Asked Questions

Levofloxacina Aurovitas contains levofloxacin, a fluoroquinolone antibiotic used intravenously to treat a variety of susceptible bacterial infections such as pneumonia, complicated urinary tract infections, skin and soft‑tissue infections, intra‑abdominal infections, and bacterial prostatitis in hospitalized patients.

Levofloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. This inhibition prevents the resealing of DNA strands, leading to bacterial cell death and effective eradication of susceptible pathogens.

The specific dose and duration of therapy are determined by the prescribing clinician based on the type and severity of infection, patient weight, renal function, and local antimicrobial guidelines. No fixed dosing information is provided here.

Levofloxacin is classified as a pregnancy category with unknown risk. It should be used during pregnancy or lactation only if the potential benefits justify the possible risks to the fetus or infant, and after careful assessment by the treating physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Levofloxacina Aurovitas belongs to the fluoroquinolone class, offering broad‑spectrum activity and excellent tissue penetration compared with many beta‑lactam antibiotics. It is often chosen for its convenient once‑daily dosing and effectiveness against both Gram‑negative and Gram‑positive organisms, though resistance patterns and safety profile must be considered.

The product should be stored at ambient temperature, below 25 °C, in its original packaging. Protect it from excessive moisture, direct sunlight, and extreme temperature fluctuations to maintain stability and potency.

Levofloxacina Aurovitas is supplied as an intravenous solution and is administered by slow infusion into a vein under the supervision of qualified healthcare professionals, following aseptic technique and appropriate infusion guidelines.

Serious risks include tendon rupture (especially Achilles tendon), QT interval prolongation leading to cardiac arrhythmias, severe hypersensitivity reactions such as Stevens‑Johnson syndrome, Clostridioides difficile‑associated colitis, and peripheral neuropathy. Patients should be monitored closely for any of these events.

Levofloxacina Aurovitas should be avoided in patients with a known hypersensitivity to levofloxacin or other fluoroquinolones, those with a history of tendon disorders related to fluoroquinolone use, and individuals with significant QT prolongation or uncontrolled cardiac arrhythmias unless benefits outweigh risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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