Product image of Levofloxacina Aurovitas (Levofloxacin) supplied by GNH India

Levofloxacina Aurovitas

Active Ingredient:
Levofloxacin
Origin:
EU

Levofloxacina Aurovitas (Levofloxacin)

Levofloxacin, the active ingredient in Levofloxacina Aurovitas, is a fluoroquinolone presented as an oral tablet for oral use. It treats a broad spectrum of bacterial infections in adult patients, including respiratory, urinary, and skin infections.
GNH India supplies Levofloxacina Aurovitas as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Generis Farmacêutica, S.A.

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Indications & Clinical Uses

Levofloxacina Aurovitas is a fluoroquinolone antibiotic used to treat bacterial infections in several organ systems.

  • Community‑acquired respiratory tract infection: eradicates susceptible pathogens and improves respiratory symptoms.
  • Urinary tract infection: clears causative bacteria and resolves urinary symptoms.
  • Skin and soft tissue infection: eliminates skin pathogens and promotes wound healing.
  • Intra‑abdominal infection: targets mixed aerobic and anaerobic organisms in the abdominal cavity.
  • Gonorrhea: provides effective antimicrobial activity against Neisseria gonorrhoeae.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. By stabilizing the enzyme‑DNA complex, it prevents the resealing of DNA strands, leading to bacterial cell death. This bactericidal action is concentration‑dependent and effective against a wide range of Gram‑positive and Gram‑negative organisms.

Side Effects

Levofloxacina Aurovitas may cause adverse reactions that vary in frequency and severity.

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Diarrhea: loose stools that may be watery.
  • Headache: transient cranial discomfort.
  • Dizziness: sensation of light‑headedness or unsteadiness.

Serious or Rare Side Effects

  • Tendon rupture: sudden tendon pain or loss of function, especially in the Achilles.
  • QT interval prolongation: potential cardiac arrhythmia risk.
  • Severe allergic reaction: rash, swelling, or anaphylaxis requiring immediate medical attention.

Precautions & Warnings

Before prescribing Levofloxacina Aurovitas, clinicians should consider several safety measures.

  • Assess renal function: adjust therapy in patients with impaired clearance.
  • Avoid use in patients with known hypersensitivity to fluoroquinolones.
  • Monitor for tendon pain or inflammation: discontinue if symptoms develop.
  • Use caution in patients with cardiac arrhythmias: QT prolongation may occur.
  • Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Levofloxacina Aurovitas can interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Antacids or supplements containing aluminum, magnesium, calcium, or iron: reduce levofloxacin absorption.
  • Warfarin: may increase anticoagulant effect and bleeding risk.
  • Cyclosporine: elevated cyclosporine levels can lead to nephrotoxicity.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): may increase risk of central nervous system stimulation.
  • Insulin: enhanced hypoglycaemic effect may require dose adjustment.
  • Oral hypoglycaemic agents: potential for increased blood‑sugar lowering; monitor glucose closely.

Frequently Asked Questions

Levofloxacina Aurovitas, containing levofloxacin, is indicated for adult patients with community‑acquired respiratory tract infections, urinary tract infections, skin and soft tissue infections, intra‑abdominal infections, and gonorrhea. It targets susceptible bacterial pathogens in these conditions and helps resolve clinical symptoms.

Levofloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. By preventing the resealing of DNA strands, it causes bacterial cell death. This mechanism provides a bactericidal effect against a broad range of Gram‑positive and Gram‑negative organisms.

The specific dose and duration of Levofloxacina Aurovitas are determined by the prescribing clinician based on the infection type, severity, patient age, renal function, and other clinical factors. Patients should follow the exact regimen provided by their healthcare professional.

Safety data for levofloxacin in pregnancy and lactation are limited. The drug should only be used if the potential benefit justifies any potential risk to the fetus or infant. Clinicians must evaluate each case individually and discuss possible risks with the patient.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Levofloxacina Aurovitas (levofloxacin) offers a broad spectrum of activity similar to other fluoroquinolones but provides once‑daily dosing for many infections due to its high bioavailability. Compared with older agents, it may have a more favorable safety profile for certain adverse events, though class‑related risks remain.

Levofloxacina Aurovitas should be stored at ambient temperature below 25 °C. Keep the tablets in the original packaging, protect them from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.

Levofloxacina Aurovitas is supplied as oral tablets and is taken by mouth with or without food, as directed by a healthcare professional. Swallow the tablet whole with a full glass of water; do not crush or chew unless specifically instructed.

Serious risks include tendon rupture (especially Achilles), QT interval prolongation leading to cardiac arrhythmias, severe allergic reactions such as anaphylaxis, and Clostridioides difficile‑associated colitis. Patients should be advised to seek immediate medical attention if they experience sudden tendon pain, palpitations, or signs of an allergic reaction.

Levofloxacina Aurovitas is contraindicated in individuals with a known hypersensitivity to levofloxacin, other fluoroquinolones, or any of the tablet excipients. It should also be avoided in patients with a history of tendon disorders related to fluoroquinolone use and in those with significant cardiac arrhythmias without careful monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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