Product image of Levofloxacina Basi (Levofloxacin) supplied by GNH India

Levofloxacina Basi

Active Ingredient:
Levofloxacin
Origin:
EU

Levofloxacina Basi (Levofloxacin)

Levofloxacin, the active ingredient in Levofloxacina Basi, is a fluoroquinolone antibiotic presented as an oral tablet for systemic use. It treats a range of bacterial infections in adults and children when prescribed by a qualified health professional.

GNH India supplies Levofloxacina Basi as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Ldp Torlan Lda.

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Indications & Clinical Uses

Levofloxacina Basi is a fluoroquinolone antibacterial used to treat infections caused by susceptible bacteria.

  • Urinary tract infection: effective for uncomplicated and complicated infections of the bladder and kidneys.
  • Community‑acquired pneumonia: clears bacterial lung infection and improves respiratory function.
  • Acute bacterial sinusitis: reduces sinus inflammation and bacterial load.
  • Acute exacerbation of chronic bronchitis: shortens symptom duration and prevents progression.
  • Skin and soft‑tissue infection: eradicates bacterial pathogens in cellulitis and wound infections.
  • Prostatitis: resolves bacterial inflammation of the prostate gland.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. By stabilizing the enzyme‑DNA complex, it prevents the resealing of DNA strands, leading to bacterial cell death and a bactericidal effect against a broad spectrum of Gram‑negative and Gram‑positive organisms.

Side Effects

Levofloxacina Basi may cause adverse reactions that vary in frequency and severity.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Diarrhea: loose stools, sometimes watery.
  • Headache: transient cranial discomfort.
  • Dizziness: occasional light‑headedness.
  • Photosensitivity: increased skin reaction to sunlight.
  • Tendon pain: mild discomfort, especially in the Achilles tendon.

Serious or Rare Side Effects

  • Tendon rupture: sudden severe pain and loss of function.
  • QT interval prolongation: risk of cardiac arrhythmia.
  • Severe allergic reaction: rash, swelling, or anaphylaxis.
  • Central nervous system effects: seizures or confusion.
  • Clostridioides difficile colitis: severe diarrhea with abdominal pain.
  • Hepatotoxicity: elevated liver enzymes or jaundice.

Precautions & Warnings

Before prescribing Levofloxacina Basi, clinicians should consider several safety factors.

  • Renal impairment: assess kidney function and adjust dose if necessary.
  • History of tendon disorders: avoid use in patients with prior tendon injury.
  • Concomitant QT‑prolonging drugs: monitor cardiac rhythm closely.
  • Pregnancy: reserve for situations where benefits outweigh potential fetal risk.
  • Age > 65 years: watch for central nervous system adverse effects.
  • Store at ambient temperature: keep in original packaging, protect from moisture and light.

Avoid Interactions

Levofloxacina Basi can interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Ciprofloxacin: combined fluoroquinolone use increases tendon rupture risk.
  • Warfarin: potentiates anticoagulant effect, raising bleeding risk.
  • Theophylline: may raise serum theophylline concentrations, causing toxicity.

Moderate Interactions (Monitor Closely)

  • NSAIDs: may enhance central nervous system side effects.
  • Antacids containing magnesium or aluminum: reduce levofloxacin absorption; separate dosing by at least 2 hours.
  • Oral hypoglycemics: may affect blood glucose control; monitor glucose levels.

Frequently Asked Questions

Levofloxacina Basi contains levofloxacin, a fluoroquinolone antibiotic indicated for urinary tract infections, community‑acquired pneumonia, acute bacterial sinusitis, exacerbations of chronic bronchitis, skin and soft‑tissue infections, and prostatitis when the causative bacteria are susceptible.

Levofloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. This inhibition prevents the resealing of DNA strands during replication, leading to bacterial cell death and a bactericidal effect across many Gram‑negative and Gram‑positive organisms.

The dosage of Levofloxacina Basi is determined by the prescribing clinician based on the type and severity of infection, patient age, renal function, and other clinical factors. Patients should follow the exact regimen provided on the prescription label.

Safety data for levofloxacin in pregnancy are limited, and the drug is generally reserved for situations where the potential benefit justifies any risk to the fetus. Breastfeeding mothers should consult a healthcare professional, as the drug can be excreted in milk.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levofloxacina Basi belongs to the fluoroquinolone class, offering broad‑spectrum coverage and convenient once‑daily oral dosing. Compared with beta‑lactams, it penetrates tissues well and is active against many resistant strains, but it carries specific safety considerations such as tendon toxicity and QT prolongation.

Levofloxacina Basi should be stored at ambient temperature, below 25 °C, in its original container. Keep the product away from moisture, direct sunlight, and heat sources to maintain stability and potency throughout its shelf life.

Levofloxacina Basi is taken orally, usually with a full glass of water. It can be taken with or without food, but antacids containing magnesium or aluminum should be spaced at least two hours apart to avoid reduced absorption.

Serious risks include tendon rupture (especially in the Achilles tendon), QT interval prolongation leading to arrhythmias, severe allergic reactions such as anaphylaxis, and Clostridioides difficile‑associated colitis. Patients should seek immediate medical attention if they experience sudden tendon pain, palpitations, or severe gastrointestinal symptoms.

Levofloxacina Basi is contraindicated in patients with a known hypersensitivity to levofloxacin or other fluoroquinolones, those with a history of tendon disorders related to fluoroquinolone use, and individuals taking medications that significantly prolong the QT interval without appropriate monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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