Product image of Levofloxacina Bruschettini (Levofloxacin Hemihydrate) supplied by GNH India

Levofloxacina Bruschettini

Active Ingredient:
Levofloxacin Hemihydrate
Origin:
EU

Levofloxacina Bruschettini (Levofloxacin Hemihydrate)

Levofloxacin, the active ingredient in Levofloxacina Bruschettini, is a fluoroquinolone antibiotic presented as an ophthalmic solution for ocular use. It treats bacterial eye infections such as conjunctivitis and keratitis in adults and children as prescribed.

GNH India supplies Levofloxacina Bruschettini as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bruschettini S.R.L

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Indications & Clinical Uses

Levofloxacina Bruschettini is a fluoroquinolone used to manage bacterial infections of the eye and related ocular tissues.

  • Bacterial conjunctivitis: reduces bacterial load and accelerates resolution of infection.
  • Bacterial keratitis: eradicates causative organisms and supports corneal healing.
  • Post‑operative ocular infection: prevents bacterial proliferation and aids recovery.
  • Other ocular bacterial infections: controls infection and reduces risk of complications.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. By blocking these targets, the drug prevents bacterial cell division and leads to rapid bacterial death in susceptible ocular pathogens.

Side Effects

Levofloxacina Bruschettini may cause ocular and systemic reactions.

Common Side Effects

  • Eye irritation or burning sensation.
  • Redness and tearing of the treated eye.
  • Transient blurred vision.
  • Mild allergic conjunctivitis.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis) with swelling or difficulty breathing.
  • Corneal ulcer worsening or perforation.
  • Tendon rupture or musculoskeletal pain (systemic exposure).
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis affecting the eye.

Precautions & Warnings

Use Levofloxacina Bruschettini with caution and follow professional guidance.

  • Allergy assessment: avoid if known hypersensitivity to fluoroquinolones.
  • Pregnancy and lactation: use only when benefits outweigh potential risks.
  • Contact lens wearers: remove lenses before administration and wait before reinserting.
  • Concurrent systemic fluoroquinolone therapy: monitor for additive toxicity.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Levofloxacina Bruschettini can interact with other ophthalmic and systemic agents.

Major Interactions (Avoid)

  • Systemic fluoroquinolones: increased risk of tendon toxicity.
  • Corticosteroid eye drops: may delay corneal healing.
  • Anticholinergic ophthalmic agents: may reduce drug absorption.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory eye drops: possible additive ocular irritation.
  • Herbal supplements containing quinine: potential additive QT‑interval prolongation.

Frequently Asked Questions

Levofloxacina Bruschettini is an ophthalmic formulation of levofloxacin used to treat bacterial infections of the eye, including bacterial conjunctivitis, bacterial keratitis, and other ocular bacterial infections. It works by eliminating the causative bacteria and helping to restore normal ocular health.

Levofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. By blocking these enzymes, the drug prevents bacterial cells from multiplying, leading to rapid bacterial death and resolution of the infection in the ocular tissues.

The dosage and frequency of Levofloxacina Bruschettini are determined by the prescribing clinician based on the specific infection, severity, and patient factors. The prescriber will provide the exact regimen on the prescription label.

Safety data for ocular levofloxacin in pregnancy and lactation are limited. It should be used only if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by the treating physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Levofloxacina Bruschettini belongs to the fluoroquinolone class, offering broad‑spectrum coverage against Gram‑negative and some Gram‑positive ocular pathogens. Compared with older agents such as ciprofloxacin or ofloxacin, levofloxacin often provides higher potency and a lower risk of resistance, though choice depends on local susceptibility patterns and clinician preference.

Store the product at room temperature, preferably below 25 °C, in its original packaging. Protect it from direct light and moisture to maintain stability. Do not freeze the solution.

The medication is applied as eye drops. The prescribed number of drops is placed into the affected eye(s) according to the dosing schedule provided by the prescriber, typically after washing hands and avoiding contact between the dropper tip and the eye or any surface.

Serious risks include severe allergic reactions such as anaphylaxis, worsening of corneal ulcers, tendon rupture (especially with systemic exposure), and rare but life‑threatening skin reactions like Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience any of these symptoms.

Individuals with a known hypersensitivity to levofloxacin, other fluoroquinolones, or any component of the formulation should avoid this product. It is also contraindicated in patients where the prescriber determines that the risks outweigh the benefits, such as certain pregnant or breastfeeding patients without a clear indication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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