Product image of Levofloxacina Farmoz (Levofloxacin) supplied by GNH India

Levofloxacina Farmoz

Active Ingredient:
Levofloxacin
Origin:
EU

Levofloxacina Farmoz (Levofloxacin)

Levofloxacin, the active ingredient in Levofloxacina Farmoz, is a fluoroquinolone antibiotic presented as an oral tablet for systemic use. It is indicated for the treatment of bacterial infections such as urinary tract infections, respiratory tract infections, skin and soft‑tissue infections, and prostatitis in adult patients.

GNH India supplies Levofloxacina Farmoz as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand. Customers benefit from reliable supply chains and comprehensive technical support.

Manufacturer / TM Owner

Farmoz - Sociedade Técnico Medicinal, S.A.

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Indications & Clinical Uses

Levofloxacin is a fluoroquinolone antibiotic used to treat bacterial infections across several organ systems.

  • Urinary tract infections: eradicates susceptible uropathogens, relieving symptoms and preventing complications.
  • Respiratory tract infections: targets common respiratory pathogens, improving cough, fever and breathing difficulties.
  • Skin and soft tissue infections: eliminates causative bacteria, aiding wound healing and reducing inflammation.
  • Prostatitis: treats bacterial prostatitis, reducing prostatic pain and urinary disturbances.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. By stabilizing the enzyme‑DNA complex, it prevents the resealing of DNA strands, leading to bacterial cell death and a bactericidal effect against a broad spectrum of Gram‑positive and Gram‑negative organisms.

Side Effects

Levofloxacin may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Diarrhea: loose stools, sometimes watery.
  • Headache: transient cranial discomfort.
  • Rash: mild skin erythema or itching.

Serious or Rare Side Effects

  • Tendon rupture: especially Achilles, requiring immediate medical attention.
  • QT interval prolongation: may predispose to cardiac arrhythmias.
  • Severe allergic reactions: including anaphylaxis and angioedema.
  • Clostridioides difficile infection: colitis with watery diarrhea.
  • Peripheral neuropathy: numbness or tingling in extremities.

Precautions & Warnings

Levofloxacin should be used with caution in specific clinical situations.

  • Renal impairment: dose adjustment may be required based on kidney function.
  • History of tendon disorders: avoid use in patients with prior tendon injury.
  • Cardiac risk: monitor patients with known QT prolongation or electrolyte disturbances.
  • Pregnancy and lactation: assess risk–benefit ratio before prescribing.
  • Store at ambient temperature: keep below 25 °C, in the original packaging, protected from moisture and light.

Avoid Interactions

Levofloxacin can interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Antacids containing aluminum or magnesium: reduce levofloxacin absorption; separate administration by at least 2 hours.
  • Warfarin: may increase anticoagulant effect; monitor INR closely.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): may increase risk of CNS stimulation.
  • Theophylline: levofloxacin can raise plasma theophylline levels, requiring dose adjustment.
  • Diabetic agents: may cause dysglycemia; monitor blood glucose regularly.

Frequently Asked Questions

Levofloxacina Farmoz contains levofloxacin, which is prescribed for bacterial urinary tract infections, respiratory tract infections such as pneumonia or bronchitis, skin and soft‑tissue infections, and bacterial prostatitis in adult patients.

Levofloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes needed for DNA replication and transcription. This inhibition prevents bacterial cells from repairing their DNA, leading to cell death and a bactericidal effect.

The specific dose and treatment duration are determined by the prescribing clinician based on the infection type, severity, patient age, renal function and other clinical factors. Patients should follow the prescriber’s instructions exactly.

Safety data are limited; levofloxacin is generally avoided in pregnancy and lactation unless the potential benefit outweighs the risk. Healthcare providers should evaluate each case individually and discuss possible alternatives.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levofloxacin offers broad‑spectrum coverage against many Gram‑positive and Gram‑negative bacteria and has the convenience of once‑daily oral dosing. Compared with older agents like ciprofloxacin, it often provides higher potency and better tissue penetration, but safety considerations such as tendon risk must be weighed.

Store the product at ambient temperature, below 25 °C, in its original container. Protect it from moisture, direct sunlight and extreme heat to maintain potency throughout its shelf life.

Levofloxacina Farmoz is taken orally, usually with a full glass of water. It can be taken with or without food, but antacids containing aluminum or magnesium should be spaced at least two hours apart to avoid reduced absorption.

Serious adverse events include tendon rupture (especially Achilles), QT interval prolongation leading to arrhythmias, severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, peripheral neuropathy, and rare hypersensitivity syndromes like Stevens‑Johnson syndrome.

Patients with a known hypersensitivity to levofloxacin or other fluoroquinolones, those with a history of tendon disorders related to fluoroquinolone use, and individuals with significant QT prolongation or uncontrolled electrolyte abnormalities should avoid this medication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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