Product image of Levofloxacina Pensa Pharma (Levofloxacin) supplied by GNH India

Levofloxacina Pensa Pharma

Active Ingredient:
Levofloxacin
Origin:
EU

Levofloxacina Pensa Pharma (Levofloxacin)

Levofloxacin, the active ingredient in Levofloxacina Pensa Pharma, is a fluoroquinolone antibiotic presented as an oral dosage form for oral use. It treats a range of bacterial infections in adult patients, including urinary, respiratory, skin, and intra‑abdominal infections.

GNH India supplies Levofloxacina Pensa Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Towa Pharmaceutical S.P.A.

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Indications & Clinical Uses

Levofloxacina Pensa Pharma is a fluoroquinolone that targets bacterial DNA replication in several infection categories.

  • Urinary tract infections: eliminates the causative bacteria, relieving symptoms and preventing recurrence.
  • Community‑acquired pneumonia: clears respiratory pathogens, improving lung function and reducing fever.
  • Skin and soft‑tissue infections: eradicates skin‑resident bacteria, promoting wound healing.
  • Prostatitis: resolves prostatic bacterial infection, alleviating pain and urinary difficulty.
  • Complicated intra‑abdominal infections: treats polymicrobial infections within the abdominal cavity, supporting recovery.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA supercoiling and replication. By binding to these enzymes, it prevents DNA synthesis and transcription, leading to bacterial cell death without affecting human topoisomerases.

Side Effects

Levofloxacina Pensa Pharma may cause adverse reactions that vary in frequency and severity.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Diarrhea: loose stools that may be self‑limiting.
  • Headache: transient cranial discomfort.
  • Dizziness: sensation of light‑headedness.

Serious or Rare Side Effects

  • Tendon rupture: sudden tendon pain or loss of function, especially in weight‑bearing tendons.
  • QT interval prolongation: potential cardiac arrhythmia risk.
  • Severe allergic reaction: hives, swelling, or anaphylaxis requiring immediate medical attention.

Precautions & Warnings

Before prescribing Levofloxacina Pensa Pharma, clinicians should consider several safety measures.

  • Assess renal function: adjust therapy if renal impairment is present.
  • Avoid in patients with known tendon disorders: risk of tendon rupture is increased.
  • Monitor cardiac status: watch for QT interval prolongation, especially with other QT‑prolonging agents.
  • Use with caution in elderly patients: higher susceptibility to adverse events.
  • Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Levofloxacina Pensa Pharma can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Co‑administration with other fluoroquinolones: additive toxicity.
  • Antacids containing aluminum or magnesium: markedly reduces levofloxacin absorption.
  • Warfarin: may potentiate anticoagulant effect, increasing bleeding risk.

Moderate Interactions (Monitor Closely)

  • NSAIDs: may increase risk of central nervous system effects.
  • Corticosteroids: heightened risk of tendon rupture.
  • Theophylline: levofloxacin can raise plasma theophylline concentrations, requiring dose adjustment.

Frequently Asked Questions

Levofloxacina Pensa Pharma is indicated for adult patients with urinary tract infections, community‑acquired pneumonia, skin and soft‑tissue infections, prostatitis, and complicated intra‑abdominal infections. It works by targeting the bacteria responsible for these conditions, helping to resolve symptoms and prevent disease progression.

Levofloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. By inhibiting these enzymes, the drug prevents bacterial cells from reproducing, leading to bacterial death while sparing human cells that use different enzymes.

The dosage of Levofloxacina Pensa Pharma is determined by the prescribing clinician based on the type and severity of infection, patient age, weight, and renal function. Only a qualified healthcare professional should set the appropriate dose and treatment duration.

Safety data for levofloxacin in pregnancy and lactation are limited. The drug should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by a healthcare provider after evaluating the clinical situation.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Levofloxacin belongs to the fluoroquinolone class, offering broad‑spectrum activity against Gram‑negative and some Gram‑positive bacteria. Compared with beta‑lactams, it provides convenient oral dosing and good tissue penetration, but it carries specific safety considerations such as tendon toxicity and QT prolongation that may influence drug selection.

Levofloxacina Pensa Pharma should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight, and excessive heat to maintain its stability and potency.

The medication is taken orally, usually with a full glass of water. It can be taken with or without food, but antacids containing aluminum, magnesium, or calcium should be spaced at least two hours apart to avoid reduced absorption.

Serious risks include tendon rupture, especially in the Achilles tendon, QT interval prolongation that may lead to cardiac arrhythmias, and severe allergic reactions such as anaphylaxis. Patients should be instructed to report sudden tendon pain, palpitations, or signs of an allergic response immediately.

Patients with a known hypersensitivity to levofloxacin or other fluoroquinolones, those with a history of tendon disorders related to fluoroquinolone use, and individuals taking medications that significantly prolong the QT interval should avoid this drug unless no alternatives exist and benefits outweigh risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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