Product image of Levofloxacine Eg (Levofloxacin) supplied by GNH India

Levofloxacine Eg

Active Ingredient:
Levofloxacin
Origin:
EU

Levofloxacine Eg (Levofloxacin)

Levofloxacin, the active ingredient in Levofloxacine Eg, is a fluoroquinolone antibiotic presented as an oral dosage form for systemic use. It treats a range of bacterial infections in adults and is prescribed based on susceptibility testing.
GNH India supplies Levofloxacine Eg as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Eg Labo Laboratoires Eurogenerics

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Indications & Clinical Uses

Levofloxacine Eg is a fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria.

  • Urinary tract infection: eradicates causative organisms and resolves urinary symptoms.
  • Respiratory tract infection: clears bacterial pathogens in conditions such as acute bronchitis and community‑acquired pneumonia.
  • Skin and soft tissue infection: eliminates bacteria responsible for cellulitis, abscesses and wound infections.
  • Prostatitis: reduces bacterial load in chronic bacterial prostatitis, improving clinical outcomes.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription and repair. By stabilizing the DNA‑enzyme complex, it prevents the resealing of DNA strands, leading to bacterial cell death. This bactericidal action is effective against a broad spectrum of Gram‑negative and Gram‑positive organisms.

Side Effects

Levofloxacine Eg may cause a range of adverse reactions.

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Diarrhea: loose stools, sometimes watery.
  • Headache: transient cranial discomfort.
  • Dizziness: feeling light‑headed or unsteady.

Serious or Rare Side Effects

  • Tendon rupture: sudden pain or loss of function, especially in the Achilles tendon.
  • QT interval prolongation: cardiac rhythm disturbances that may cause palpitations.
  • Severe allergic reaction: rash, swelling, or difficulty breathing requiring immediate medical attention.

Precautions & Warnings

Before prescribing Levofloxacine Eg, clinicians should consider several safety factors.

  • Renal impairment: adjust dose or monitor renal function closely.
  • History of tendon disorders: avoid use in patients with prior tendon injury or those on corticosteroids.
  • Cardiac risk: caution in patients with known QT prolongation or electrolyte abnormalities.
  • Pregnancy and lactation: use only if benefits outweigh potential risks, as safety data are limited.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, and protect from moisture.

Avoid Interactions

Levofloxacine Eg can interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Antacids containing aluminum or magnesium: reduce levofloxacin absorption; separate administration by at least 2 hours.
  • Warfarin: may increase anticoagulant effect; monitor INR closely.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): may increase risk of central nervous system stimulation.
  • Theophylline: levofloxacin can raise plasma theophylline levels; monitor for toxicity.
  • Diabetic agents (e.g., insulin, sulfonylureas): may cause hypoglycemia; observe blood glucose regularly.

Frequently Asked Questions

Levofloxacine Eg is prescribed for bacterial infections such as urinary tract infections, respiratory tract infections (including bronchitis and pneumonia), skin and soft‑tissue infections, and chronic bacterial prostatitis, provided the causative organisms are susceptible to levofloxacin.

Levofloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes needed for DNA replication and transcription. This inhibition prevents the bacteria from repairing their DNA, leading to cell death and eradication of the infection.

The dosage of Levofloxacine Eg is determined by the prescribing clinician based on the type and severity of infection, patient age, renal function and local susceptibility patterns. Patients should follow the exact regimen provided by their healthcare professional.

Safety data for levofloxacin in pregnancy and lactation are limited. It should only be used when the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levofloxacin belongs to the fluoroquinolone class, offering broad‑spectrum coverage and convenient once‑daily dosing for many infections. Compared with beta‑lactams, it may be more effective against resistant Gram‑negative organisms but carries specific safety considerations such as tendon toxicity and QT prolongation.

Levofloxacine Eg should be stored at ambient temperature, below 25 °C, in its original container to protect it from moisture and light. Keep the product out of reach of children and do not use it after the expiration date.

Levofloxacine Eg is taken orally, usually with a full glass of water. It can be taken with or without food, but antacids containing aluminum or magnesium should be spaced at least two hours apart to avoid reduced absorption.

Serious adverse effects include tendon rupture, especially of the Achilles tendon, QT interval prolongation leading to cardiac arrhythmias, and severe hypersensitivity reactions such as anaphylaxis. Patients should seek immediate medical attention if they experience sudden tendon pain, palpitations, or signs of an allergic reaction.

Levofloxacine Eg is contraindicated in patients with a known hypersensitivity to levofloxacin or other fluoroquinolones. It should also be avoided in individuals with a history of tendon disorders related to fluoroquinolone use, and used with caution in patients with significant cardiac arrhythmias or uncontrolled epilepsy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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