Levofloxacine Evolugen (Levofloxacin)

Levofloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. This inhibition prevents bacterial DNA from unwinding and resealing, leading to bacterial cell death and a bactericidal effect against susceptible organisms.

The dosage of Levofloxacine Evolugen is determined by the prescribing clinician based on the infection type, severity, patient age, renal function and other clinical factors. No fixed regimen is provided here; the prescriber sets the appropriate dose.

Levofloxacine Evolugen is classified as Pregnancy Category C, meaning risk cannot be ruled out. It should be used only if the potential benefit to the mother outweighs any possible risk to the fetus. Caution is also advised during breastfeeding, and a healthcare professional should evaluate the risk‑benefit balance.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Compared with older fluoroquinolones, levofloxacin offers once‑daily dosing and a broader spectrum against Gram‑negative and some Gram‑positive pathogens. It is generally more potent than ciprofloxacin and has better lung penetration than many macrolides, making it a preferred option for certain respiratory infections, though safety considerations differ.

Store the tablets at room temperature, below 25 °C, in the original blister pack or container. Protect them from moisture, excessive heat and direct sunlight. Do not refrigerate or freeze the product, and keep it out of reach of children.

Levofloxacine Evolugen is taken orally with a full glass of water. It may be taken with or without food, but antacids or mineral supplements should be spaced at least two hours apart to avoid reduced absorption. Swallow the tablet whole; do not crush or chew.

Serious adverse events include tendon rupture or tendinitis, especially in older adults or those on corticosteroids; QT‑interval prolongation leading to arrhythmias; severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome; Clostridioides difficile‑associated colitis; peripheral neuropathy; and hepatic dysfunction. Prompt medical attention is required if any of these occur.

Levofloxacine Evolugen is contraindicated in patients with a known hypersensitivity to levofloxacin, other fluoroquinolones, or any component of the formulation. It should be avoided in children and adolescents unless no alternative therapy exists, and used with caution in pregnant or breastfeeding women, patients with a history of tendon disorders, and those with significant cardiac arrhythmias.