Product image of Levofloxacine Sandoz (Levofloxacin) supplied by GNH India

Levofloxacine Sandoz

Active Ingredient:
Levofloxacin
Origin:
EU

Levofloxacine Sandoz (Levofloxacin)

Levofloxacin, the active ingredient in Levofloxacine Sandoz, is a fluoroquinolone antibiotic presented as an oral dosage form for systemic use. It treats a range of bacterial infections in adults and adolescents, including urinary, respiratory, and skin infections.

GNH India supplies Levofloxacine Sandoz as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance.

Manufacturer / TM Owner

Sandoz N.V.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Levofloxacine Sandoz is a fluoroquinolone antibiotic used to treat bacterial infections in several organ systems.

  • Urinary tract infections: eradicates susceptible uropathogens and resolves symptoms of cystitis and pyelonephritis.
  • Respiratory tract infections: treats community‑acquired pneumonia and acute exacerbations of chronic bronchitis.
  • Skin and soft tissue infections: clears infections caused by Gram‑negative and Gram‑positive bacteria.
  • Prostatitis: eliminates bacterial involvement in chronic bacterial prostatitis.
  • Sinusitis: resolves acute bacterial sinus inflammation.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. By stabilizing the DNA‑enzyme complex, it prevents the resealing of DNA strands, leading to bacterial cell death and a bactericidal effect against susceptible organisms.

Side Effects

Levofloxacine Sandoz may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Diarrhea: loose stools, sometimes watery.
  • Headache: transient cranial discomfort.
  • Dizziness: sensation of light‑headedness.
  • Abdominal pain: cramping or discomfort in the stomach area.

Serious or Rare Side Effects

  • Tendon rupture: sudden tendon pain or swelling, especially in the Achilles.
  • QT interval prolongation: risk of cardiac arrhythmias.
  • Severe allergic reactions: rash, swelling, or anaphylaxis.
  • Clostridioides difficile infection: severe colitis with watery diarrhea.
  • Peripheral neuropathy: numbness or tingling in extremities.

Precautions & Warnings

Before prescribing Levofloxacine Sandoz, clinicians should consider several safety measures.

  • Assess renal function: dose adjustment may be required in impaired kidneys.
  • Avoid use in patients with known hypersensitivity to fluoroquinolones.
  • Monitor for tendon pain or inflammation, especially in older adults.
  • Use caution in patients with a history of QT prolongation or arrhythmias.
  • Avoid concomitant use with non‑steroidal anti‑inflammatory drugs when possible due to increased tendon risk.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Levofloxacine Sandoz can interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Concurrent use with other fluoroquinolones: increased toxicity risk.
  • Co‑administration with drugs that prolong the QT interval (e.g., macrolides, antiarrhythmics): heightened arrhythmia potential.
  • Combination with antacids or supplements containing aluminum, magnesium, calcium, or iron: reduces levofloxacin absorption.

Moderate Interactions (Monitor Closely)

  • Corticosteroids: may increase tendon rupture risk.
  • Warfarin: levofloxacin can enhance anticoagulant effect, requiring INR monitoring.
  • Theophylline: plasma concentrations may rise, necessitating dosage adjustment.

Frequently Asked Questions

Levofloxacine Sandoz is a prescription fluoroquinolone antibiotic indicated for the treatment of bacterial infections such as urinary tract infections, respiratory tract infections, skin and soft‑tissue infections, prostatitis, and acute sinusitis. It is used in adults and adolescents when the causative organisms are susceptible.

Levofloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. By preventing the resealing of DNA strands, it halts bacterial cell division and leads to bacterial death, providing a bactericidal effect against a broad spectrum of Gram‑negative and Gram‑positive organisms.

The dosage of Levofloxacine Sandoz is determined by the prescribing clinician based on the specific infection, patient age, renal function, and other clinical factors. Only a qualified healthcare professional can set the appropriate dose and treatment duration.

Safety data for levofloxacin during pregnancy and lactation are limited. The drug should be used only if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by the prescribing physician after evaluating the individual situation.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Levofloxacin offers a broad spectrum of activity similar to other fluoroquinolones such as ciprofloxacin, but it has enhanced potency against many Gram‑positive organisms and better lung tissue penetration, making it a preferred option for respiratory infections. Choice of agent depends on susceptibility patterns, infection site, and patient‑specific factors.

Store Levofloxacine Sandoz at room temperature, below 25 °C, in the original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing it in humid or excessively hot environments.

Levofloxacine Sandoz is taken orally, usually with a full glass of water. It can be taken with or without food, but if antacids or mineral supplements are used, they should be spaced at least two hours apart to avoid reduced absorption.

Serious risks include tendon rupture (especially the Achilles tendon), QT interval prolongation leading to cardiac arrhythmias, severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, and peripheral neuropathy. Patients should be advised to seek immediate medical attention if they experience sudden tendon pain, palpitations, or severe skin reactions.

Levofloxacine Sandoz should be avoided in individuals with a known hypersensitivity to levofloxacin or any fluoroquinolone, those with a history of tendon disorders related to fluoroquinolone use, patients with significant QT prolongation, and individuals receiving concomitant therapy that markedly increases the risk of tendon injury.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Levofloxacin

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT