Product image of Levofloxacine Stada (Levofloxacin Hemihydrate) supplied by GNH India

Levofloxacine Stada

Active Ingredient:
Levofloxacin Hemihydrate
Origin:
EU

Levofloxacine Stada (Levofloxacin Hemihydrate)

Levofloxacin, the active ingredient in Levofloxacine Stada, is a fluoroquinolone antibiotic presented as an oral dosage form for systemic use. It treats a range of bacterial infections, including urinary tract, respiratory, and skin infections, in adult patients as determined by a healthcare professional. It is available only by prescription and should be used under medical supervision.

GNH India supplies Levofloxacine Stada as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies and clinics across EU and other global markets.

Manufacturer / TM Owner

Stada Arzneimittel Ag

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Indications & Clinical Uses

Levofloxacine Stada is a fluoroquinolone antibiotic used to treat bacterial infections in various organ systems.

  • Urinary tract infection: eradicates susceptible bacteria, relieving symptoms and preventing complications.
  • Community‑acquired pneumonia: eliminates the causative pathogens, improving respiratory function.
  • Skin and soft tissue infection: clears infection and promotes wound healing.
  • Prostatitis: reduces bacterial load in the prostate, alleviating pain and urinary symptoms.
  • Complicated intra‑abdominal infection: targets mixed aerobic and anaerobic organisms to control infection.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. By binding to these enzymes, it prevents the supercoiling and separation of DNA strands, leading to bacterial cell death. The drug exhibits concentration‑dependent bactericidal activity against a broad spectrum of Gram‑positive and Gram‑negative organisms.

Side Effects

Levofloxacine Stada may cause a range of adverse reactions.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Diarrhea: loose stools that may be self‑limiting.
  • Headache: transient cranial discomfort.
  • Dizziness: sensation of light‑headedness.

Serious or Rare Side Effects

  • Tendon rupture: sudden pain and loss of function, especially in the Achilles.
  • QT interval prolongation: risk of cardiac arrhythmias.
  • Severe allergic reaction: rash, swelling, or anaphylaxis.
  • Clostridioides difficile colitis: severe diarrhea with abdominal cramping.
  • Hepatic dysfunction: elevated liver enzymes or jaundice.
  • Peripheral neuropathy: tingling or numbness in extremities.

Precautions & Warnings

Before prescribing Levofloxacine Stada, clinicians should consider several safety factors.

  • Renal function: adjust dose in patients with severe impairment.
  • History of tendon disorders: avoid use in individuals with recent tendon injury.
  • QT prolongation risk: monitor ECG in patients with cardiac conduction abnormalities.
  • Pregnancy and lactation: use only if benefits outweigh potential risks.
  • Drug interactions: review concomitant medications for possible effects.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Levofloxacine Stada can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Antacids containing magnesium or aluminum: markedly reduce levofloxacin absorption.
  • Ciprofloxacin or other fluoroquinolones: additive QT‑prolonging effect.
  • Warfarin: may increase anticoagulant effect and bleeding risk.

Moderate Interactions (Monitor Closely)

  • NSAIDs: heightened risk of central nervous system stimulation.
  • Theophylline: levofloxacin can raise serum theophylline levels.
  • Oral hypoglycemics: possible alteration of blood glucose control.

Frequently Asked Questions

Levofloxacine Stada is indicated for a variety of bacterial infections, including uncomplicated urinary tract infections, community‑acquired pneumonia, skin and soft‑tissue infections, prostatitis, and complicated intra‑abdominal infections. The choice of therapy depends on the susceptibility of the causative organism and the clinical judgment of the prescribing physician.

Levofloxacin blocks two essential bacterial enzymes, DNA gyrase and topoisomerase IV, which are required for DNA replication and transcription. By inhibiting these enzymes, the drug prevents bacterial DNA from unwinding and separating, leading to bacterial cell death and eradication of the infection.

The dosage of Levofloxacine Stada is determined by the prescribing clinician based on the type and severity of the infection, patient age, renal function, and other clinical factors. Patients should follow the exact dosing instructions provided on the prescription label.

Safety data for levofloxacin in pregnancy and lactation are limited. The drug should be used only if the potential benefits justify the possible risks to the fetus or infant. Healthcare providers will assess individual circumstances before prescribing to pregnant or nursing women.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Levofloxacin offers a broad spectrum of activity against both Gram‑positive and Gram‑negative bacteria and has a convenient once‑daily dosing regimen for many infections. Compared with older fluoroquinolones, it often provides higher potency against respiratory pathogens and a more favorable safety profile, though class‑related risks such as tendon injury remain.

Levofloxacine Stada should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight, and excessive heat to maintain its stability and potency.

Levofloxacine Stada is taken orally, usually with a full glass of water. It can be taken with or without food, but antacids containing magnesium or aluminum should be spaced at least two hours apart to avoid reduced absorption.

Serious adverse events include tendon rupture, especially of the Achilles tendon, QT interval prolongation leading to cardiac arrhythmias, severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, and peripheral neuropathy. Patients should be instructed to seek immediate medical attention if they experience sudden tendon pain, palpitations, or severe skin reactions.

Levofloxacine Stada is contraindicated in patients with a known hypersensitivity to levofloxacin or other fluoroquinolones. It should also be avoided in individuals with a history of tendon disorders related to fluoroquinolone therapy, those with significant QT prolongation, and patients receiving concomitant medications that may cause dangerous drug interactions without proper monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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