Product image of Levofloxacino Almus (Levofloxacin Hemihydrate) supplied by GNH India

Levofloxacino Almus

Active Ingredient:
Levofloxacin Hemihydrate
Origin:
EU

Levofloxacino Almus (Levofloxacin Hemihydrate)

Levofloxacin, the active ingredient in Levofloxacino Almus, is a fluoroquinolone antibiotic presented as a tablet for oral use. It treats bacterial infections of the respiratory, urinary, and skin systems in adult patients.
GNH India supplies Levofloxacino Almus as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Almus Farmaceutica S.A.

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Indications & Clinical Uses

Levofloxacino Almus is a fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria.

  • Respiratory tract infections: effective for community‑acquired pneumonia and acute exacerbations of chronic bronchitis.
  • Urinary tract infections: clears uncomplicated cystitis and pyelonephritis.
  • Skin and soft tissue infections: resolves cellulitis, wound infections and abscesses.
  • Sinusitis: treats acute bacterial sinusitis.
  • Prostatitis: used for chronic bacterial prostatitis.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. By stabilizing the enzyme‑DNA complex, it prevents the resealing of DNA strands, leading to bacterial cell death. The drug exhibits concentration‑dependent bactericidal activity against a broad spectrum of Gram‑positive and Gram‑negative organisms.

Side Effects

Levofloxacino Almus may cause a range of adverse reactions.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Diarrhea: loose stools, sometimes watery.
  • Headache: transient cranial discomfort.
  • Dizziness: sensation of light‑headedness.
  • Insomnia: difficulty falling or staying asleep.
  • Photosensitivity: increased skin sensitivity to sunlight.

Serious or Rare Side Effects

  • Tendon rupture: especially Achilles tendon, often linked to sudden activity.
  • QT interval prolongation: may predispose to cardiac arrhythmias.
  • Clostridioides difficile infection: severe colitis after gut flora disruption.
  • Severe allergic reactions: rash, angioedema, or anaphylaxis.
  • Peripheral neuropathy: numbness or tingling in extremities.
  • Hepatic dysfunction: elevated liver enzymes or hepatitis.

Precautions & Warnings

Levofloxacino Almus requires careful assessment before use.

  • Assess renal function: dose may need adjustment in patients with impaired clearance.
  • Evaluate cardiac risk: avoid in patients with known QT prolongation or arrhythmias.
  • Review tendon health: discontinue if tendon pain or swelling occurs.
  • Monitor for C. difficile: watch for persistent diarrhea after therapy.
  • Store at ambient temperature: keep below 25 °C, in the original packaging, protected from moisture.

Avoid Interactions

Levofloxacino Almus can interact with several medicines.

Major Interactions (Avoid)

  • Antacids containing magnesium or aluminum: reduce levofloxacin absorption.
  • Warfarin: may increase anticoagulant effect and bleeding risk.
  • Cyclosporine: heightened serum levels of both agents.
  • Theophylline: increased theophylline concentrations leading to toxicity.

Moderate Interactions (Monitor Closely)

  • NSAIDs: combined use may raise risk of central nervous system stimulation.
  • Corticosteroids: concurrent use can increase tendon rupture risk.
  • Diabetic agents: may affect glucose control; monitor blood sugar.

Frequently Asked Questions

Levofloxacino Almus is prescribed for bacterial infections such as community‑acquired pneumonia, acute exacerbations of chronic bronchitis, uncomplicated urinary tract infections, skin and soft‑tissue infections, acute bacterial sinusitis, and chronic bacterial prostatitis. It targets susceptible Gram‑positive and Gram‑negative organisms in these conditions.

Levofloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes needed for DNA replication and transcription. By preventing the resealing of DNA strands, it halts bacterial cell division and leads to rapid bacterial death, providing a broad‑spectrum bactericidal effect.

The specific dose and duration of Levofloxacino Almus are determined by the prescribing clinician based on the type and severity of infection, patient age, renal function, and other clinical factors. Patients should follow the exact regimen provided by their healthcare professional.

Safety data for levofloxacin in pregnancy and lactation are limited. It is generally avoided unless the potential benefit justifies the potential risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives with their healthcare provider.

To request Levofloxacino Almus, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Levofloxacin belongs to the fluoroquinolone class, offering broad‑spectrum coverage and convenient once‑daily oral dosing, which can be advantageous over some beta‑lactams that require multiple daily doses. However, fluoroquinolones carry specific risks such as tendon injury and QT prolongation, so clinicians weigh benefits against these safety considerations when selecting therapy.

Levofloxacino Almus should be stored at ambient temperature, below 25 °C, in its original packaging to protect from moisture and light. Keep the product out of reach of children and avoid storing in humid or excessively hot environments.

Levofloxacino Almus is taken orally, usually with a full glass of water. It may be taken with or without food, but patients should avoid simultaneous intake of antacids containing magnesium or aluminum, as these can reduce absorption. Swallow tablets whole; do not crush or chew unless instructed otherwise.

Serious risks include tendon rupture (especially the Achilles tendon), QT interval prolongation leading to cardiac arrhythmias, severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, peripheral neuropathy, and hepatic injury. Patients should seek immediate medical attention if they experience sudden tendon pain, palpitations, severe rash, or persistent diarrhea.

Levofloxacino Almus is contraindicated in patients with a known hypersensitivity to levofloxacin, other fluoroquinolones, or any of the product’s excipients. It should also be avoided in individuals with a history of tendon disorders related to fluoroquinolone use, uncontrolled cardiac arrhythmias, or those taking medications that significantly prolong the QT interval.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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