Product image of Levofloxacino Alter (Levofloxacin) supplied by GNH India

Levofloxacino Alter

Active Ingredient:
Levofloxacin
Origin:
EU

Levofloxacino Alter (Levofloxacin)

Levofloxacin, the active ingredient in Levofloxacino Alter, is a fluoroquinolone antibiotic presented as an oral dosage form for systemic use. It treats a range of bacterial infections in adults and children when prescribed by a qualified healthcare professional.

GNH India supplies Levofloxacino Alter as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratorios Alter, S.A.

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Indications & Clinical Uses

Levofloxacino Alter is a fluoroquinolone used to treat bacterial infections affecting several organ systems.

  • Urinary tract infection: effective bacterial eradication in uncomplicated and complicated UTIs.
  • Community‑acquired respiratory infection: clears pathogens in pneumonia and acute bronchitis.
  • Skin and soft‑tissue infection: resolves cellulitis and wound infections.
  • Acute bacterial prostatitis: eliminates causative organisms in prostate infection.
  • Complicated intra‑abdominal infection: provides coverage for mixed aerobic and anaerobic bacteria.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. By stabilizing the enzyme‑DNA complex, it prevents the resealing of DNA strands, leading to bacterial cell death. This bactericidal action is broad‑spectrum, affecting Gram‑negative, Gram‑positive, and atypical pathogens.

Side Effects

Levofloxacino Alter may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Nausea: mild gastrointestinal upset.
  • Diarrhea: loose stools, occasionally watery.
  • Headache: transient cranial discomfort.
  • Dizziness: sensation of light‑headedness.
  • Abdominal pain: cramping or discomfort.
  • Rash: mild skin erythema.

Serious or Rare Side Effects

  • Tendon rupture: sudden pain and loss of function, especially in the Achilles.
  • QT interval prolongation: risk of cardiac arrhythmias.
  • Severe allergic reactions: anaphylaxis, angioedema, or Stevens‑Johnson syndrome.
  • Clostridioides difficile infection: severe colitis with watery diarrhea.
  • Hepatic toxicity: elevated liver enzymes or jaundice.
  • Peripheral neuropathy: numbness or tingling in extremities.

Precautions & Warnings

Before prescribing Levofloxacino Alter, clinicians should consider several safety aspects.

  • Renal function: adjust dose in patients with severe impairment.
  • Cardiac health: avoid in individuals with known QT prolongation or concurrent QT‑prolonging drugs.
  • Tendon health: advise patients to report tendon pain or swelling promptly.
  • Photosensitivity: recommend sun protection measures during therapy.
  • Pregnancy and lactation: use only when benefits outweigh potential risks.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Levofloxacino Alter can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Antacids containing aluminum or magnesium: markedly reduce levofloxacin absorption.
  • Warfarin: may increase anticoagulant effect and bleeding risk.
  • Theophylline: can raise serum theophylline concentrations, leading to toxicity.
  • Other fluoroquinolones: concurrent use adds to toxicity without benefit.

Moderate Interactions (Monitor Closely)

  • NSAIDs: may increase risk of central nervous system adverse effects.
  • Diabetes medications (insulin, sulfonylureas): potential for enhanced hypoglycemia.
  • Corticosteroids: may elevate risk of tendon rupture when combined.

Frequently Asked Questions

Levofloxacino Alter, containing levofloxacin, is indicated for urinary tract infections, community‑acquired respiratory infections such as pneumonia and bronchitis, skin and soft‑tissue infections, acute bacterial prostatitis, and complicated intra‑abdominal infections. It is prescribed when a broad‑spectrum antibacterial agent is required.

Levofloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes that unwind and reseal DNA during replication and transcription. By stabilizing the enzyme‑DNA complex, it prevents DNA synthesis, leading to bacterial cell death. This mechanism provides bactericidal activity against a wide range of Gram‑negative, Gram‑positive, and atypical organisms.

The specific dose of Levofloxacino Alter is determined by the prescribing clinician based on the infection type, severity, patient age, renal function, and other clinical factors. Healthcare professionals follow local guidelines and product labeling to select the appropriate regimen.

Safety data for levofloxacin in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Clinicians must evaluate each case individually and discuss alternatives when possible.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Levofloxacino Alter (levofloxacin) offers once‑daily dosing and a broad spectrum that includes many Gram‑negative and atypical pathogens, often providing higher potency against respiratory organisms compared with older agents like ciprofloxacin. Its pharmacokinetic profile allows convenient dosing, but safety considerations such as tendon risk are shared across the class.

Levofloxacino Alter should be stored at room temperature, below 25 °C, in its original packaging. Protect the product from moisture, excessive heat, and direct sunlight to maintain stability throughout its shelf life.

Levofloxacino Alter is taken orally, usually with a full glass of water. It can be taken with or without food, but antacids containing aluminum, magnesium, calcium, or iron should be spaced at least two hours apart to avoid reduced absorption.

Serious risks include tendon rupture (especially Achilles), QT interval prolongation leading to cardiac arrhythmias, severe hypersensitivity reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, and rare cases of hepatic toxicity or peripheral neuropathy. Patients should be instructed to seek immediate medical attention if they experience related symptoms.

Levofloxacino Alter is contraindicated in patients with a known hypersensitivity to levofloxacin, other fluoroquinolones, or any component of the formulation. It should also be avoided in individuals with a history of tendon disorders related to fluoroquinolone use, uncontrolled arrhythmias, or those taking medications that significantly prolong the QT interval.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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