Product image of Levofloxacino Cinfa (Levofloxacin) supplied by GNH India

Levofloxacino Cinfa

Active Ingredient:
Levofloxacin
Origin:
EU

Levofloxacino Cinfa (Levofloxacin)

Levofloxacin, the active ingredient in Levofloxacino Cinfa, is a fluoroquinolone antibiotic presented as an oral dosage form for systemic use. It treats a range of bacterial infections in adults and children when prescribed by a qualified health professional.

GNH India supplies Levofloxacino Cinfa as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratorios Cinfa S.A.

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Indications & Clinical Uses

Levofloxacino Cinfa is a fluoroquinolone antibiotic used to treat bacterial infections affecting several organ systems.

  • Respiratory tract infections: eradicates the causative bacteria and improves breathing symptoms.
  • Urinary tract infections: clears infection and reduces urinary discomfort.
  • Skin and soft tissue infections: eliminates pathogenic organisms and promotes wound healing.
  • Sinusitis: resolves sinus inflammation caused by susceptible bacteria.
  • Prostatitis: treats bacterial inflammation of the prostate gland.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication and transcription. By binding to these enzymes, it prevents the unwinding and resealing of DNA strands, leading to bacterial cell death and suppression of infection growth.

Side Effects

Levofloxacino Cinfa may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Nausea: mild stomach upset.
  • Diarrhea: loose stools, often self‑limiting.
  • Headache: transient cranial discomfort.
  • Dizziness: occasional light‑headedness.
  • Rash: mild skin erythema.
  • Photosensitivity: increased sun sensitivity.

Serious or Rare Side Effects

  • Tendon rupture: sudden pain and loss of function, especially in the Achilles.
  • QT prolongation: cardiac rhythm disturbances.
  • Severe hypersensitivity: anaphylaxis or Stevens‑Johnson syndrome.
  • Central nervous system effects: seizures or hallucinations.
  • Hepatotoxicity: elevated liver enzymes or jaundice.
  • Peripheral neuropathy: tingling or numbness in extremities.

Precautions & Warnings

Before prescribing Levofloxacino Cinfa, clinicians should consider several safety aspects.

  • Renal impairment: adjust dose or monitor renal function.
  • Hepatic disease: use with caution in patients with liver dysfunction.
  • History of tendon disorders: avoid in patients with prior tendon injury.
  • Cardiac risk: monitor QT interval in patients with arrhythmia risk.
  • Pregnancy and breastfeeding: use only if clearly needed, as safety data are limited.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture.

Avoid Interactions

Levofloxacino Cinfa can affect or be affected by other medicines.

Major Interactions (Avoid)

  • Antacids containing aluminum or magnesium: reduce absorption of levofloxacin.
  • Warfarin: may increase anticoagulant effect and bleeding risk.
  • NSAIDs (e.g., ibuprofen): heightened risk of central nervous system stimulation.

Moderate Interactions (Monitor Closely)

  • Corticosteroids: increased chance of tendon rupture.
  • Theophylline: possible elevation of plasma theophylline levels.
  • Cyclosporine: may raise cyclosporine concentrations.

Frequently Asked Questions

Levofloxacino Cinfa is indicated for bacterial respiratory tract infections, urinary tract infections, skin and soft‑tissue infections, acute sinusitis, and chronic bacterial prostatitis. It is prescribed when the causative organisms are susceptible to levofloxacin and when alternative agents are unsuitable.

Levofloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. Inhibiting these targets prevents bacterial cells from duplicating their genetic material, leading to bacterial death and resolution of the infection.

The dosage of Levofloxacino Cinfa is determined by the prescribing clinician based on the infection type, severity, patient age, renal function, and other clinical factors. Patients should follow the exact regimen provided by their health‑care professional.

Safety data for levofloxacin in pregnancy and lactation are limited, and the product is classified as pregnancy category unknown. It should only be used when clearly needed and after a risk‑benefit assessment by the prescriber. Breastfeeding mothers should consult their physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Levofloxacin is a third‑generation fluoroquinolone with broad‑spectrum activity against Gram‑negative and Gram‑positive bacteria. Compared with older agents like ciprofloxacin, levofloxacin offers once‑daily dosing for many infections and a slightly improved safety profile, though class‑related warnings such as tendon risk remain.

Levofloxacino Cinfa should be stored at ambient temperature, below 25 °C. Keep the product in its original container, protect it from moisture and direct sunlight, and ensure the packaging remains sealed until use.

Levofloxacino Cinfa is taken orally, usually with a full glass of water. It can be taken with or without food, but antacids containing aluminum or magnesium should be spaced at least two hours apart to avoid reduced absorption.

Serious risks include tendon rupture (especially in the Achilles), QT interval prolongation leading to cardiac arrhythmias, severe hypersensitivity reactions such as anaphylaxis or Stevens‑Johnson syndrome, and central nervous system effects like seizures. Patients should seek immediate medical attention if these events occur.

Levofloxacino Cinfa is contraindicated in patients with a known hypersensitivity to levofloxacin or other fluoroquinolones. It should also be avoided in individuals with a history of tendon disorders related to fluoroquinolone use, and in patients receiving concomitant medications that may cause dangerous QT prolongation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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