Product image of Levofloxacino Mabo-Farma (Levofloxacin) supplied by GNH India

Levofloxacino Mabo-Farma

Active Ingredient:
Levofloxacin
Origin:
EU

Levofloxacino Mabo-Farma (Levofloxacin)

Levofloxacin, the active ingredient in Levofloxacino Mabo-Farma, is a fluoroquinolone antibiotic presented as an oral dosage form for oral use. It treats a range of bacterial infections in adults and children when prescribed by a qualified health professional.

GNH India supplies Levofloxacino Mabo-Farma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Mabo-Farma, S.A

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Indications & Clinical Uses

  • Levofloxacin is a broad‑spectrum antibacterial that targets common bacterial pathogens in several organ systems.
  • Community‑acquired respiratory tract infections: eradicates causative bacteria to resolve pneumonia and bronchitis symptoms.
  • Acute bacterial sinusitis: reduces sinus inflammation by eliminating the infecting organisms.
  • Acute exacerbations of chronic bronchitis: improves lung function by clearing bacterial load.
  • Uncomplicated urinary tract infections: achieves rapid bacterial clearance and symptom relief.
  • Skin and soft‑tissue infections: treats cellulitis and wound infections caused by susceptible strains.
  • Prostatitis: penetrates prostatic tissue to eradicate chronic bacterial infection.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. By stabilizing the enzyme‑DNA complex, it prevents the resealing of DNA strands, leading to bacterial cell death. This bactericidal action is effective against a wide range of Gram‑positive and Gram‑negative organisms.

Side Effects

Levofloxacino Mabo-Farma may cause a variety of adverse reactions.

Common Side Effects

  • Nausea or vomiting
  • Diarrhea or abdominal pain
  • Headache or dizziness
  • Insomnia or mild sleep disturbances
  • Rash or mild skin itching

Serious or Rare Side Effects

  • Tendon rupture or tendinitis, especially in the Achilles tendon
  • QT interval prolongation leading to cardiac arrhythmias
  • Clostridioides difficile‑associated colitis
  • Severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome
  • Hepatotoxicity with elevated liver enzymes

Precautions & Warnings

  • Before initiating therapy, consider the following safety measures.
  • Renal function: adjust dosage in patients with severe renal impairment.
  • History of tendon disorders: avoid use in individuals with prior tendon injury.
  • QT prolongation risk: monitor ECG in patients with cardiac risk factors.
  • Concurrent antacids or supplements: separate administration by at least 2 hours to ensure absorption.
  • Pregnancy and lactation: use only if potential benefits outweigh risks.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Levofloxacin can interact with several medicines, requiring careful management.

Major Interactions (Avoid)

  • Antacids containing magnesium or aluminum: markedly reduce levofloxacin absorption.
  • Warfarin: may increase anticoagulant effect and bleeding risk.
  • Cyclosporine: can raise cyclosporine serum concentrations.

Moderate Interactions (Monitor Closely)

  • Theophylline: levofloxacin may increase plasma theophylline levels.
  • Corticosteroids: combined use raises the risk of tendon rupture.
  • NSAIDs: may potentiate central nervous system stimulation and seizures.

Frequently Asked Questions

Levofloxacino Mabo-Farma contains levofloxacin, a fluoroquinolone antibiotic used to treat a variety of bacterial infections such as community‑acquired respiratory tract infections, acute bacterial sinusitis, urinary tract infections, skin and soft‑tissue infections, and prostatitis when prescribed by a qualified health professional.

Levofloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes that are essential for DNA replication and transcription. This inhibition prevents bacterial cells from repairing their DNA, leading to bacterial death and resolution of the infection.

The appropriate dose of Levofloxacino Mabo-Farma is determined by the prescribing clinician based on the specific infection, patient age, renal function, and other clinical factors. Patients should follow the exact dosing instructions provided by their healthcare provider.

Safety data for levofloxacin in pregnancy and lactation are limited. It should only be used when the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by the treating physician in consultation with the patient.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levofloxacin offers broad‑spectrum coverage against many Gram‑positive and Gram‑negative bacteria and has excellent tissue penetration, making it a convenient once‑daily oral option. Compared with macrolides or beta‑lactams, it may be more effective against resistant strains but carries a distinct safety profile that requires monitoring.

Levofloxacino Mabo-Farma should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the product away from moisture, heat and direct sunlight to maintain its stability and potency.

The medication is taken orally, usually with a full glass of water. It can be taken with or without food, but if antacids or mineral supplements are used, they should be spaced at least two hours apart to avoid reduced absorption.

Serious adverse events include tendon rupture or tendinitis, especially in the Achilles tendon, QT‑interval prolongation leading to cardiac arrhythmias, severe hypersensitivity reactions such as anaphylaxis or Stevens‑Johnson syndrome, and Clostridioides difficile‑associated colitis. Patients should seek immediate medical attention if these occur.

Levofloxacino Mabo-Farma should be avoided in individuals with a known hypersensitivity to levofloxacin or other fluoroquinolones, a history of tendon disorders related to fluoroquinolone use, and in patients with certain cardiac conditions that predispose to QT prolongation. Pregnant or breastfeeding women should only use it when clearly indicated by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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