Product image of Levofloxacino Sandoz (Levofloxacin) supplied by GNH India

Levofloxacino Sandoz

Active Ingredient:
Levofloxacin
Origin:
EU

Levofloxacino Sandoz (Levofloxacin)

Levofloxacin, the active ingredient in Levofloxacino Sandoz, is a fluoroquinolone antibiotic presented as an oral tablet for oral use. It treats a range of bacterial infections in adults and children when prescribed by a healthcare professional.

GNH India supplies Levofloxacino Sandoz as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution. It offers flexible ordering options and supports regulatory compliance for importers in multiple regions.

Manufacturer / TM Owner

Sandoz Farmacéutica, S.A.

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Indications & Clinical Uses

Levofloxacin is a fluoroquinolone antibiotic used to treat bacterial infections in several organ systems.

  • Community‑acquired respiratory tract infection: reduces bacterial load and improves clinical symptoms.
  • Urinary tract infection: eradicates causative uropathogens and relieves urinary discomfort.
  • Skin and soft tissue infection: eliminates skin pathogens and promotes wound healing.
  • Intra‑abdominal infection: targets mixed bacterial flora to resolve abdominal sepsis.
  • Gonorrhea: clears Neisseria gonorrhoeae and prevents disease transmission.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. By binding to these enzymes, it prevents the supercoiling and separation of DNA strands, leading to bacterial cell death. This bactericidal action is effective against a broad spectrum of Gram‑negative and Gram‑positive organisms.

Side Effects

Levofloxacin may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Nausea: mild gastrointestinal upset.
  • Diarrhea: loose stools, often self‑limiting.
  • Headache: transient cranial discomfort.
  • Dizziness: sensation of light‑headedness.

Serious or Rare Side Effects

  • Tendon rupture: sudden tendon pain or loss of function.
  • QT interval prolongation: risk of cardiac arrhythmia.
  • Clostridioides difficile infection: severe colitis with watery diarrhea.

Precautions & Warnings

Before prescribing Levofloxacino Sandoz, clinicians should consider several safety factors.

  • Renal impairment: adjust dose as recommended by prescriber.
  • History of tendon disorders: avoid use or monitor closely for tendon pain.
  • Cardiac arrhythmia risk: caution in patients with known QT prolongation.
  • Pregnancy and lactation: use only if benefits outweigh potential risks.
  • Drug interactions: review concomitant medications for potential interactions.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Levofloxacino Sandoz can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Concurrent fluoroquinolones: increased risk of toxicity.
  • QT‑prolonging agents (e.g., macrolides, antiarrhythmics): heightened arrhythmia risk.
  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): may reduce antibacterial activity.

Moderate Interactions (Monitor Closely)

  • Warfarin: may enhance anticoagulant effect; monitor INR.
  • Theophylline: increased plasma levels; watch for toxicity.
  • Corticosteroids: elevated risk of tendon rupture; monitor symptoms.

Frequently Asked Questions

Levofloxacino Sandoz, containing levofloxacin, is indicated for community‑acquired respiratory tract infections, urinary tract infections, skin and soft tissue infections, intra‑abdominal infections, and gonorrhea. It is prescribed by a qualified healthcare professional to target susceptible bacterial pathogens in these conditions.

Levofloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. This inhibition prevents bacterial cells from replicating their DNA, leading to cell death and elimination of the infection.

The dosage of Levofloxacino Sandoz is determined by the prescribing clinician based on the specific infection, patient age, weight, renal function, and other clinical factors. Patients should follow the exact regimen provided by their healthcare professional.

The safety of levofloxacin in pregnancy and lactation is not well established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and this decision must be made by a qualified prescriber.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levofloxacino Sandoz contains levofloxacin, a third‑generation fluoroquinolone with a broad spectrum of activity and once‑daily dosing options. Compared with older fluoroquinolones, it often offers improved potency against Gram‑negative organisms and a more favorable safety profile, though class‑related warnings still apply.

Levofloxacino Sandoz should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight, and excessive heat to maintain its stability and potency.

Levofloxacino Sandoz is administered orally, typically as a tablet taken with or without food as directed by the prescriber. The exact timing and whether to take it with meals depend on the individual treatment plan.

Serious risks include tendon rupture, especially in the Achilles tendon, QT interval prolongation leading to cardiac arrhythmias, and severe Clostridioides difficile‑associated diarrhea. Patients should be advised to report sudden tendon pain, palpitations, or persistent diarrhea promptly.

Levofloxacino Sandoz should be avoided in patients with a known hypersensitivity to levofloxacin or other fluoroquinolones, those with a history of tendon disorders related to fluoroquinolone use, and individuals with significant QT prolongation unless benefits outweigh risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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