Product image of Levofloxacino Tarbis Farma (Levofloxacin Hemihydrate) supplied by GNH India

Levofloxacino Tarbis Farma

Active Ingredient:
Levofloxacin Hemihydrate
Origin:
EU

Levofloxacino Tarbis Farma (Levofloxacin Hemihydrate)

Levofloxacin, the active ingredient in Levofloxacino Tarbis Farma, is a fluoroquinolone antibiotic presented as an oral dosage form for systemic use. It treats a range of bacterial infections in adults and children when prescribed by a qualified healthcare professional and works by inhibiting bacterial DNA replication.
GNH India supplies Levofloxacino Tarbis Farma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Tarbis Farma, S.L.

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Indications & Clinical Uses

  • Levofloxacino Tarbis Farma, a fluoroquinolone antibiotic, is indicated for several bacterial infections affecting different organ systems.
  • Community‑acquired pneumonia: effective in eradicating the causative pathogens and improving respiratory symptoms.
  • Acute bacterial sinusitis: reduces sinus inflammation and clears infection.
  • Urinary tract infection: eliminates uropathogens and resolves urinary symptoms.
  • Skin and soft‑tissue infection: treats cellulitis, abscesses and other bacterial skin conditions.
  • Acute exacerbation of chronic bronchitis: decreases bacterial load and aids recovery of lung function.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA supercoiling and replication. By binding to these enzymes, it prevents the unwinding and resealing of DNA strands, halting bacterial DNA synthesis and transcription, which leads to bacterial cell death. The drug exhibits concentration‑dependent bactericidal activity against a broad spectrum of Gram‑negative and Gram‑positive organisms.

Side Effects

Levofloxacino Tarbis Farma may cause adverse reactions that vary in frequency and severity.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Diarrhea: loose stools, sometimes watery.
  • Headache: transient cranial discomfort.
  • Dizziness: sensation of light‑headedness or unsteadiness.

Serious or Rare Side Effects

  • Tendon rupture: sudden pain or loss of function, especially in the Achilles tendon.
  • QT interval prolongation: may lead to cardiac arrhythmias.
  • Severe allergic reaction: rash, swelling, difficulty breathing.
  • Clostridioides difficile infection: severe colitis with watery diarrhea.
  • Peripheral neuropathy: numbness or tingling in extremities.

Precautions & Warnings

  • Before prescribing Levofloxacino Tarbis Farma, clinicians should consider several safety measures.
  • Renal function assessment: adjust dose in patients with impaired clearance.
  • Hypersensitivity: avoid in individuals with known allergy to fluoroquinolones.
  • Tendon health: discontinue if tendon pain, swelling or inflammation occurs.
  • Elderly patients: monitor closely for central nervous system effects such as confusion or seizures.
  • Store at room temperature: keep in the original container, protect from moisture.

Avoid Interactions

Levofloxacino Tarbis Farma can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Antacids containing aluminum or magnesium: reduce levofloxacin absorption.
  • Warfarin: may increase anticoagulant effect and bleeding risk.
  • Systemic corticosteroids: heightened risk of tendon rupture.

Moderate Interactions (Monitor Closely)

  • QT‑prolonging agents: monitor cardiac rhythm for arrhythmias.
  • Oral contraceptives: efficacy may be reduced; consider alternative contraception.

Frequently Asked Questions

Levofloxacino Tarbis Farma contains levofloxacin, a fluoroquinolone antibiotic used to treat bacterial infections such as community‑acquired pneumonia, acute bacterial sinusitis, urinary tract infections, and skin and soft‑tissue infections. It is prescribed when the responsible bacteria are susceptible and when an oral antimicrobial is appropriate.

Levofloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. By preventing these enzymes from resealing DNA strands, the drug stops bacterial cells from multiplying, leading to bacterial death and resolution of the infection.

The dosage is determined by the prescribing clinician based on the type and severity of infection, patient age, weight, renal function, and other clinical factors. Only a qualified healthcare professional can set the appropriate dose and treatment duration.

Safety data in pregnancy and lactation are limited. Levofloxacin is generally avoided unless the potential benefit to the mother outweighs any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Levofloxacin is a third‑generation fluoroquinolone with a broad spectrum covering many Gram‑negative and Gram‑positive pathogens. Compared with older agents like ciprofloxacin, it often requires once‑daily dosing and has enhanced activity against Streptococcus pneumoniae. However, safety considerations such as tendon toxicity and QT prolongation are similar across the class.

Store the product at room temperature, below 25 °C, in the original packaging to protect it from moisture and light. Keep the container tightly closed and out of reach of children. Do not refrigerate or freeze the tablets.

Levofloxacino Tarbis Farma is taken orally, usually with a full glass of water. It may be taken with or without food, but antacids or supplements containing calcium, magnesium, aluminum, or iron should be spaced at least two hours apart to avoid reduced absorption.

Serious adverse events include tendon rupture (especially in the Achilles tendon), QT interval prolongation leading to arrhythmias, severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, and peripheral neuropathy. Patients should seek immediate medical attention if they experience sudden tendon pain, palpitations, severe rash, or neurological symptoms.

Individuals with a known hypersensitivity to levofloxacin or any fluoroquinolone should avoid the product. It is also contraindicated in patients with a history of tendon disorders related to fluoroquinolone use, those with uncontrolled cardiac arrhythmias, and patients taking medications that significantly prolong the QT interval without careful monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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