Product image of Levofloxacino Teva (Levofloxacin) supplied by GNH India

Levofloxacino Teva

Active Ingredient:
Levofloxacin
Origin:
EU

Levofloxacino Teva (Levofloxacin)

Levofloxacin, the active ingredient in Levofloxacino Teva, is a fluoroquinolone antibiotic presented as an oral tablet for systemic use. It is indicated for the treatment of community‑acquired respiratory tract infections, acute bacterial sinusitis, acute exacerbations of chronic bronchitis, urinary tract infections, and skin and soft‑tissue infections in adults and children as prescribed by a healthcare professional.

GNH India supplies Levofloxacino Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company follows Good Distribution Practice and provides regulatory‑compliant documentation to support import and clinical use.

Manufacturer / TM Owner

Teva Pharma S.L.U.,

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Indications & Clinical Uses

Levofloxacino Teva, a fluoroquinolone antibiotic, is used to treat bacterial infections affecting several organ systems.

  • Community‑acquired respiratory tract infection: reduces bacterial load and improves clinical symptoms.
  • Acute bacterial sinusitis: eradicates causative pathogens and relieves sinus inflammation.
  • Acute exacerbation of chronic bronchitis: shortens duration of exacerbation and improves lung function.
  • Urinary tract infection: eliminates uropathogens and resolves urinary symptoms.
  • Skin and soft‑tissue infection: treats bacterial skin infections and promotes healing.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication and transcription. By binding to these enzymes, it prevents the supercoiling and relaxation of bacterial DNA, leading to inhibition of bacterial cell division and ultimately bacterial cell death. This bactericidal activity is effective against a broad spectrum of Gram‑negative and Gram‑positive organisms.

Side Effects

Levofloxacino Teva may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Nausea: mild stomach upset that may resolve without intervention.
  • Diarrhea: loose stools that are usually self‑limiting.
  • Headache: transient head pain often relieved with rest.
  • Dizziness: feeling of light‑headedness or unsteadiness.

Serious or Rare Side Effects

  • Tendon rupture: sudden tendon pain or swelling, especially in the Achilles.
  • QT interval prolongation: cardiac rhythm disturbance that can lead to arrhythmia.
  • Severe allergic reaction: rash, swelling, or breathing difficulty requiring urgent care.
  • Clostridioides difficile‑associated colitis: severe diarrhea with abdominal pain and fever.

Precautions & Warnings

Before prescribing Levofloxacino Teva, clinicians should consider several safety factors.

  • Renal impairment: dose adjustment may be required based on kidney function.
  • History of tendon disorders: avoid use or monitor closely for tendon pain.
  • Cardiac arrhythmias: caution due to potential QT prolongation.
  • Pregnancy and lactation: use only if benefits outweigh potential risks.
  • Drug interactions: review concomitant medications for major interactions.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Levofloxacino Teva can interact with other medicines, altering its efficacy or safety.

Major Interactions (Avoid)

  • Antacids containing aluminum or magnesium: reduce levofloxacin absorption.
  • Ciprofloxacin: additive QT prolongation risk.
  • Warfarin: increased anticoagulant effect, may raise INR.

Moderate Interactions (Monitor Closely)

  • Theophylline: may increase serum levels, watch for toxicity.
  • NSAIDs: heightened risk of central nervous system stimulation.
  • Cyclosporine: may raise levofloxacin concentrations, monitor renal function.

Frequently Asked Questions

Levofloxacino Teva contains levofloxacin, a fluoroquinolone antibiotic indicated for the treatment of community‑acquired respiratory tract infections, acute bacterial sinusitis, acute exacerbations of chronic bronchitis, urinary tract infections, and skin and soft‑tissue infections. It is prescribed for adults and children when a bacterial cause is identified or strongly suspected.

Levofloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes that are essential for DNA replication and transcription. This inhibition prevents bacterial DNA from unwinding and rewinding, leading to a halt in bacterial cell division and ultimately bacterial cell death.

The dosage of Levofloxacino Teva is determined by the prescribing healthcare professional based on the specific infection, patient age, weight, renal function, and other clinical factors. No fixed dose is provided here; the prescriber will set the appropriate regimen.

Safety data for levofloxacin in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Healthcare providers should discuss individual risk factors and consider alternative therapies when appropriate.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details, and any necessary import documentation.

Levofloxacino Teva belongs to the fluoroquinolone class, offering broad‑spectrum activity against many Gram‑negative and Gram‑positive bacteria. Compared with macrolides or beta‑lactams, fluoroquinolones often achieve higher tissue penetration and a rapid bactericidal effect, but they carry specific safety considerations such as tendon toxicity and QT prolongation.

Levofloxacino Teva should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing it in humid or excessively hot environments.

Levofloxacino Teva is administered orally, usually as a tablet taken with a full glass of water. It can be taken with or without food, but if antacids containing aluminum or magnesium are used, they should be spaced at least two hours apart to avoid reduced absorption.

The most serious adverse events include tendon rupture or tendinitis, especially in the Achilles tendon, QT interval prolongation that may lead to arrhythmias, severe allergic reactions such as anaphylaxis, and Clostridioides difficile‑associated colitis. Patients should be instructed to seek immediate medical attention if they experience any of these symptoms.

Levofloxacino Teva should be avoided in individuals with a known hypersensitivity to levofloxacin or other fluoroquinolones, those with a history of tendon disorders related to fluoroquinolone use, patients with certain cardiac conditions that predispose to QT prolongation, and in pregnant or breastfeeding women unless the benefit clearly outweighs the risk.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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