Product image of Levofloxacino Vir (Levofloxacin) supplied by GNH India

Levofloxacino Vir

Active Ingredient:
Levofloxacin
Origin:
EU

Levofloxacino Vir (Levofloxacin)

Levofloxacin, the active ingredient in Levofloxacino Vir, is a fluoroquinolone antibiotic presented as an oral tablet for systemic use. It treats a range of bacterial infections in adults, including respiratory, urinary tract and skin infections, as well as community‑acquired and hospital‑acquired infections, by targeting bacterial DNA replication.

GNH India supplies Levofloxacino Vir as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides comprehensive regulatory documentation for importers.

Manufacturer / TM Owner

Industria Química Y Farmaceútica Vir, S.A.

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Indications & Clinical Uses

Levofloxacino Vir (levofloxacin) is used to treat bacterial infections across several organ systems.

  • Community‑acquired pneumonia: eradicates the causative bacteria and improves respiratory symptoms.
  • Acute bacterial sinusitis: relieves sinus inflammation and clears infection.
  • Uncomplicated urinary tract infection: eliminates uropathogens and resolves urinary symptoms.
  • Acute bacterial skin and skin‑structure infections: reduces bacterial load and promotes wound healing.
  • Acute bacterial exacerbation of chronic bronchitis: controls bacterial flare‑up and improves breathing.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA supercoiling and replication. By binding to these enzymes, it prevents the unwinding of bacterial DNA, halting transcription and cell division, which leads to bacterial cell death. The drug exhibits concentration‑dependent bactericidal activity against a broad spectrum of Gram‑negative and Gram‑positive organisms.

Side Effects

Levofloxacino Vir may cause a range of adverse reactions.

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Diarrhea: loose stools, sometimes watery.
  • Headache: transient cranial discomfort.
  • Dizziness: sensation of light‑headedness.
  • Insomnia: difficulty falling or staying asleep.
  • Abdominal pain: cramping or discomfort in the stomach area.

Serious or Rare Side Effects

  • Tendon rupture: sudden tendon pain or loss of function, especially in the Achilles.
  • QT interval prolongation: risk of cardiac arrhythmias.
  • Severe allergic reactions: rash, swelling, or anaphylaxis.
  • Clostridioides difficile infection: severe colitis with watery diarrhea.
  • Hepatic toxicity: elevated liver enzymes or jaundice.
  • Peripheral neuropathy: numbness or tingling in extremities.

Precautions & Warnings

Before prescribing Levofloxacino Vir, clinicians should consider several safety factors.

  • Renal function: adjust dose in severe impairment to avoid accumulation.
  • Age: use cautiously in elderly patients due to increased tendon‑injury risk.
  • Photosensitivity: advise patients to limit excessive sunlight exposure.
  • Concomitant QT‑prolonging drugs: monitor cardiac rhythm closely.
  • Pregnancy and lactation: prescribe only when benefits outweigh potential risks.
  • Store at below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Levofloxacino Vir can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Concurrent use with other fluoroquinolones: increased risk of toxicity.
  • Co‑administration with systemic corticosteroids: heightened risk of tendon rupture.
  • Combination with QT‑prolonging agents (e.g., quinidine, macrolides): risk of serious arrhythmias.

Moderate Interactions (Monitor Closely)

  • Antacids containing aluminum or magnesium: may reduce levofloxacin absorption.
  • Warfarin: may enhance anticoagulant effect, requiring INR monitoring.
  • Theophylline: may increase serum theophylline levels, risking toxicity.

Frequently Asked Questions

Levofloxacino Vir contains levofloxacin, a fluoroquinolone antibiotic indicated for several bacterial infections such as community‑acquired pneumonia, acute bacterial sinusitis, uncomplicated urinary tract infections, acute bacterial skin and skin‑structure infections, and exacerbations of chronic bronchitis.

Levofloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. By preventing DNA supercoiling, the drug stops bacterial cells from multiplying, leading to rapid bactericidal activity against a broad range of Gram‑negative and Gram‑positive organisms.

The dosage of Levofloxacino Vir is determined by the prescribing clinician based on the specific infection, patient weight, renal function and other clinical factors. Only a qualified health professional should set the dose and duration of therapy.

Levofloxacino Vir is classified as a pregnancy‑category unknown drug. It should be used during pregnancy or lactation only when the potential benefit justifies the potential risk to the fetus or infant, and after a thorough risk‑benefit assessment by the prescriber.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with older agents such as ciprofloxacin, levofloxacin offers broader gram‑positive coverage and once‑daily dosing for many infections. It is often preferred over macrolides for respiratory infections due to its higher potency against typical pathogens, but resistance patterns and patient factors guide final selection.

Levofloxacino Vir should be stored at temperatures below 25 °C, in its original packaging, and protected from moisture and direct sunlight. Maintaining these conditions helps preserve tablet potency throughout its shelf life.

Levofloxacino Vir is taken orally, usually with a full glass of water. It can be taken with or without food, but patients should avoid concurrent intake of antacids containing aluminum or magnesium, as these may reduce absorption.

Serious risks include tendon rupture (especially the Achilles), QT‑interval prolongation leading to arrhythmias, severe allergic reactions, Clostridioides difficile‑associated colitis, hepatic toxicity, and peripheral neuropathy. Patients should be advised to seek immediate medical attention if they experience sudden tendon pain, palpitations, rash, or persistent diarrhea.

Levofloxacino Vir is contraindicated in patients with a known hypersensitivity to levofloxacin or other fluoroquinolones. Caution is also advised for individuals with a history of tendon disorders, uncontrolled arrhythmias, or those taking medications that significantly prolong the QT interval.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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