Levomentis (Levomepromazine Maleate)

Levomepromazine works by blocking dopamine D2 receptors, which reduces psychotic activity. It also antagonises histamine H1, muscarinic acetylcholine and alpha‑adrenergic receptors, providing sedation, anti‑emetic effects and anticholinergic actions that together help control agitation, nausea and other distressing symptoms.

The appropriate dose of Levomentis is determined by the prescribing clinician based on the individual patient's condition, response, age, renal function and other factors. Dosage regimens are not standardized in public information and must be set by a qualified health‑care professional.

Safety data for levomepromazine during pregnancy and lactation are limited. It should only be used when the potential therapeutic benefit justifies any possible risk to the fetus or infant, and the decision must be made by the treating physician in consultation with the patient.

To request Levomentis, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any temperature‑controlled requirements) and the necessary import documentation.

Levomentis belongs to the phenothiazine class, similar to chlorpromazine. Compared with chlorpromazine, levomepromazine has a broader receptor profile, offering stronger antihistamine and anticholinergic effects, which can provide additional sedation and anti‑emetic benefits but may also increase the likelihood of anticholinergic side effects.

Levomentis should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid exposing it to excessive heat or humidity, which could affect its stability.

Levomentis is administered orally. The tablet (or other oral form) should be swallowed whole with a glass of water, unless the prescriber advises otherwise. It can be taken with or without food, but consistent timing helps maintain stable blood levels.

The most serious risks include neuroleptic malignant syndrome, a potentially fatal reaction characterized by high fever, muscle rigidity and autonomic instability; tardive dyskinesia, which may cause irreversible involuntary movements; severe hypotension and cardiac arrhythmias, especially in patients taking other QT‑prolonging drugs.

Levomentis should be avoided in patients with known hypersensitivity to levomepromazine or other phenothiazines, in those with severe cardiovascular disease prone to arrhythmias, and in individuals with a history of neuroleptic malignant syndrome. Caution is also advised for patients with uncontrolled glaucoma, severe liver impairment, or significant anticholinergic burden.