Levomethadone Hydrochloride Molteni (Levomethadone Hydrochloride)

Levomethadone acts as a full agonist at the µ‑opioid receptor, delivering potent analgesic and anti‑craving effects. It also blocks NMDA receptors, which may lessen the development of tolerance and modulate neuropathic pain pathways, resulting in a dual mechanism that supports both pain control and opioid‑dependence treatment.

The specific dose of Levomethadone Hydrochloride is individualized and set by the prescribing clinician based on the patient’s condition, prior opioid exposure, and response to therapy. Dosage adjustments are made according to clinical judgment and patient monitoring.

Safety data for Levomethadone in pregnancy and lactation are limited. Because it crosses the placenta and may be present in breast milk, it should be used only if the potential benefit justifies the potential risk to the fetus or infant. Consultation with a specialist is recommended.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levomethadone is the levorotatory enantiomer of methadone and provides similar opioid agonist activity with potentially reduced cardiotoxicity and fewer drug‑interaction concerns. Both are µ‑opioid receptor agonists, but Levomethadone’s NMDA antagonism may offer advantages in tolerance management and neuropathic pain.

Store the product at room temperature, below 25 °C, in its original packaging. Keep it away from moisture and direct sunlight. Ensure the container is tightly closed to maintain stability and protect from accidental ingestion.

Levomethadone Hydrochloride is administered orally, typically as a tablet or capsule, and should be taken with or without food as directed by the prescriber. Swallow the dosage form whole; do not crush or chew unless specifically instructed.

The most serious risks include respiratory depression, especially when combined with other CNS depressants, QT interval prolongation that can lead to cardiac arrhythmias, severe hypotension, seizures, and rare but potentially life‑threatening allergic reactions. Patients should be monitored closely for these events.

Levomethadone is contraindicated in individuals with known hypersensitivity to levomethadone or any component of the formulation, in patients with severe respiratory insufficiency, uncontrolled asthma, or significant cardiac conduction disorders. Caution is also advised for those with a history of severe liver disease or recent opioid overdose.