Product image of Levonance 30 (Ethinylestradiol, Levonorgestrel) supplied by GNH India

Levonance 30

Active Ingredient:
Ethinylestradiol, Levonorgestrel
Origin:
EU

Levonance 30 (Ethinylestradiol, Levonorgestrel)

Ethinylestradiol/Levonorgestrel, the active ingredient in Levonance 30, is a combined oral contraceptive presented as a tablet for oral use. It works to prevent pregnancy in women of reproductive age by inhibiting ovulation and altering cervical mucus.

GNH India supplies Levonance 30 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable access to this hormonal contraceptive. The company adheres to EU quality standards and ensures consistent product availability across global markets.

Manufacturer / TM Owner

Acis Arzneimittel Gmbh

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Indications & Clinical Uses

  • Levonance 30, a combined oral contraceptive, is indicated for hormonal contraception.
  • Prevention of pregnancy: provides reliable contraceptive protection for women of childbearing potential.
  • Contraception: used as a primary method to avoid unintended pregnancy.
  • Family planning: enables women to plan and space pregnancies according to personal goals.

How It Works

  • Ethinylestradiol and levonorgestrel act on the hypothalamic‑pituitary‑ovarian axis, suppressing the surge of luteinizing hormone and follicle‑stimulating hormone, thereby preventing follicular development and ovulation. The estrogen component stabilises the endometrium, while the progestogen thickens cervical mucus and induces endometrial changes that are unfavorable for implantation.

Side Effects

Levonance 30 may cause a range of adverse reactions, varying in frequency and severity.

Common Side Effects

  • Nausea: mild stomach upset or queasiness.
  • Breast tenderness: swelling or discomfort in the breasts.
  • Headache: mild to moderate head pain.
  • Spotting: irregular uterine bleeding between periods.

Serious or Rare Side Effects

  • Thromboembolic events: blood clots in veins or arteries, potentially life‑threatening.
  • Hepatic adenoma: benign liver tumor that may require monitoring.
  • Severe hypertension: markedly elevated blood pressure requiring medical attention.
  • Allergic reactions: rash, swelling, or anaphylaxis in rare cases.

Precautions & Warnings

Before prescribing Levonance 30, clinicians should consider several precautionary measures.

  • Contraindications: known or suspected pregnancy, active thromboembolic disease, estrogen‑dependent tumor, uncontrolled hypertension, severe liver disease.
  • Smoking: avoid use in women over 35 who smoke due to increased cardiovascular risk.
  • Medication review: assess concomitant drugs that may reduce contraceptive efficacy.
  • Regular monitoring: check blood pressure and lipid profile periodically during therapy.
  • Store at ambient temperature: keep below 25°C, protect from moisture and light in the original packaging.

Avoid Interactions

Levonance 30 can interact with other medicines, affecting its effectiveness or safety.

Major Interactions (Avoid)

  • Strong enzyme inducers (e.g., rifampin, carbamazepine): may significantly lower hormone levels and reduce contraceptive protection.
  • Certain antiretrovirals (e.g., efavirenz): can decrease oral contraceptive efficacy.
  • Hormonal therapies (e.g., hormone replacement): may increase risk of thromboembolic events.

Moderate Interactions (Monitor Closely)

  • Some antibiotics (e.g., ampicillin, tetracycline): possible modest reduction in contraceptive effect.
  • Selective serotonin reuptake inhibitors (SSRIs): may heighten risk of mood changes or bleeding.

Frequently Asked Questions

Levonance 30 is a combined oral contraceptive used to prevent pregnancy in women of reproductive age. It provides a reliable, reversible method of hormonal contraception by inhibiting ovulation and creating cervical mucus conditions that are unfavorable for sperm penetration.

The two hormones act together on the hypothalamic‑pituitary‑ovarian axis. Ethinylestradiol suppresses the release of follicle‑stimulating hormone, while levonorgestrel suppresses luteinizing hormone, preventing the mid‑cycle surge that triggers ovulation. Additionally, levonorgestrel thickens cervical mucus and alters the endometrium, reducing the chance of implantation.

The dosing regimen for Levonance 30 is determined by the prescribing healthcare professional. Typically, the product is taken once daily at the same time each day, following the specific schedule indicated on the prescription label.

Levonance 30 is contraindicated in pregnancy (Category X) and should not be started or continued by women who are pregnant. While limited data exist for breastfeeding, the progestin component may pass into breast milk; clinicians usually advise caution and consider alternative contraception for nursing mothers.

To order Levonance 30, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levonance 30 contains the standard dose combination of ethinylestradiol and levonorgestrel, a widely used progestin. Its efficacy, safety profile, and side‑effect spectrum are comparable to other products in the same class, though individual tolerability may vary based on patient-specific factors.

Levonance 30 tablets should be stored at ambient temperature, below 25 °C, in their original blister pack. Keep them away from moisture, direct sunlight, and excessive heat to maintain product stability throughout its shelf life.

Levonance 30 is taken orally, usually once a day, at the same time each day. The tablets are swallowed whole with water and should be started according to the prescribing clinician’s instructions, often on the first day of the menstrual cycle.

Serious risks include thromboembolic events such as deep‑vein thrombosis or pulmonary embolism, severe hypertension, hepatic adenoma, and rare allergic reactions. Patients should seek immediate medical attention if they experience unexplained leg pain, shortness of breath, severe headache, visual changes, or signs of an allergic reaction.

Women with known or suspected pregnancy, active or past thromboembolic disease, estrogen‑dependent tumors, uncontrolled hypertension, severe liver disease, or those who smoke and are over 35 years old should avoid Levonance 30. A thorough medical history is essential before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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