Product image of Levonic-Opto (Levofloxacin) supplied by GNH India

Levonic-Opto

Active Ingredient:
Levofloxacin
Origin:
EU

Levonic-Opto (Levofloxacin)

Levofloxacin, the active ingredient in Levonic-Opto, is a fluoroquinolone antibiotic presented as an ophthalmic solution for ocular use. It is employed to treat bacterial eye infections such as conjunctivitis and keratitis in adult and pediatric patients.

GNH India supplies Levonic-Opto as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A.

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Indications & Clinical Uses

Levofloxacin ophthalmic solution is indicated for bacterial infections of the eye and related postoperative prophylaxis.

  • Bacterial conjunctivitis: reduces bacterial load and speeds symptom resolution.
  • Bacterial keratitis: eradicates causative organisms and promotes corneal healing.
  • Corneal ulcer: prevents progression of infection and supports tissue repair.
  • Post‑surgical prophylaxis: lowers risk of infection after ocular surgery.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication and transcription. By binding to these targets, it prevents bacterial cell division and leads to bacterial cell death, providing a broad‑spectrum antibacterial effect against Gram‑positive and Gram‑negative ocular pathogens.

Side Effects

Levofloxacin ophthalmic solution may cause local and systemic adverse reactions.

Common Side Effects

  • Burning or stinging sensation upon instillation.
  • Redness of the conjunctiva.
  • Temporary blurred vision.
  • Tearing or increased lacrimation.
  • Mild eye irritation.

Serious or Rare Side Effects

  • Corneal ulceration or perforation.
  • Severe allergic reaction (e.g., angioedema, anaphylaxis).
  • Tendon rupture (systemic exposure).
  • Peripheral neuropathy.
  • Phototoxic skin reactions.

Precautions & Warnings

Levofloxacin ophthalmic solution should be used with caution and under professional supervision.

  • Allergy assessment: avoid if known hypersensitivity to fluoroquinolones.
  • Pregnancy: safety not established; use only if benefit outweighs risk.
  • Breastfeeding: limited data; consider potential infant exposure.
  • Contact lens wearers: remove lenses before administration and wait before reinserting.
  • Systemic absorption: monitor for rare systemic fluoroquinolone effects.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Levofloxacin ophthalmic solution can interact with other medications, affecting safety or efficacy.

Major Interactions (Avoid)

  • Systemic fluoroquinolones: additive risk of tendon rupture and QT prolongation.
  • Anticholinergic eye drops: may reduce ocular absorption.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory eye drops: increased risk of corneal irritation.
  • Corticosteroid eye preparations: may mask signs of infection.
  • Drugs that prolong QT interval: monitor cardiac rhythm if systemic exposure is possible.

Frequently Asked Questions

Levonics-Opto is an ophthalmic solution containing levofloxacin, a fluoroquinolone antibiotic. It is used to treat bacterial eye infections such as conjunctivitis, keratitis, and corneal ulcers, and may be employed as prophylaxis after ocular surgery.

Levofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. By blocking these enzymes, it stops bacterial cell division, leading to bacterial death and resolution of the infection.

The dosing regimen for Levonic-Opto is determined by the prescribing clinician based on the specific infection, severity, and patient factors. The product is supplied as an ophthalmic solution to be instilled according to the prescriber’s instructions.

Safety data for levofloxacin use in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by a qualified healthcare professional.

To order Levonic-Opto, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Levonics-Opto offers broad‑spectrum coverage against Gram‑positive and Gram‑negative ocular pathogens, similar to other fluoroquinolone eye drops such as moxifloxacin. Compared with older agents like chloramphenicol, levofloxacin generally provides higher potency and a lower risk of resistance, though choice depends on local susceptibility patterns and clinician preference.

Levonics-Opto should be stored at ambient temperature, below 25 °C, in its original container. Protect the solution from moisture and direct sunlight. Do not freeze the product, and keep the vial tightly sealed when not in use.

Levonics-Opto is applied as eye drops. The prescribed number of drops is placed into the conjunctival sac of the affected eye(s) using the provided dropper, typically several times a day as directed by the prescriber. Patients should avoid touching the dropper tip to the eye or any surface.

Serious risks, though rare, include corneal ulceration or perforation, severe allergic reactions such as anaphylaxis, and systemic fluoroquinolone effects like tendon rupture or QT‑interval prolongation. Patients should seek immediate medical attention if they experience severe eye pain, vision changes, or systemic symptoms.

Levonics-Opto should not be used by individuals with a known hypersensitivity to levofloxacin, other fluoroquinolones, or any component of the formulation. Caution is also advised for patients with a history of tendon disorders, cardiac arrhythmias, or those taking medications that prolong the QT interval.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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