Product image of Levonic-Opto (Levofloxacin) supplied by GNH India

Levonic-Opto

Active Ingredient:
Levofloxacin
Origin:
EU

Levonic-Opto (Levofloxacin)

Levofloxacin, the active ingredient in Levonic-Opto, is a fluoroquinolone presented as an ophthalmic solution for ocular use. It treats bacterial eye infections such as conjunctivitis, keratitis and corneal ulcers in patients requiring topical antibiotic therapy.

GNH India supplies Levonic-Opto as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance across markets. The company adheres to EU Good Manufacturing Practice and provides reliable logistics for global distribution, meeting stringent pharmacopeial standards and packaging to maintain sterility.

Manufacturer / TM Owner

Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A.

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Indications & Clinical Uses

Levofloxacin is a broad‑spectrum antibacterial used in ophthalmology to treat bacterial infections of the eye.

  • Bacterial conjunctivitis: reduces symptoms and clears infection.
  • Bacterial keratitis: eradicates causative organisms and promotes corneal healing.
  • Corneal ulcer: controls bacterial proliferation and supports ulcer resolution.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication and transcription. By binding to these enzymes, it prevents bacterial DNA supercoiling and separation, leading to inhibition of bacterial cell division and ultimately bacterial death. The drug exhibits concentration‑dependent bactericidal activity against a wide range of Gram‑positive and Gram‑negative ocular pathogens.

Side Effects

Levofloxacin ophthalmic solution may cause local ocular reactions and, rarely, systemic or severe ocular adverse events.

Common Side Effects

  • Eye irritation or burning sensation.
  • Redness of the conjunctiva.
  • Tearing or increased lacrimation.
  • Foreign body sensation.
  • Blurred vision.
  • Mild eyelid edema.

Serious or Rare Side Effects

  • Allergic reactions such as swelling, rash or urticaria.
  • Severe eye pain or corneal edema.
  • Vision loss or sudden decrease in visual acuity.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Endophthalmitis (rare infection inside the eye).

Precautions & Warnings

Levofloxacin ophthalmic solution should be used with caution and under professional supervision.

  • Allergy assessment: avoid in patients with known fluoroquinolone hypersensitivity.
  • Corneal integrity: monitor for delayed healing in compromised corneas.
  • Contact lens use: discontinue lenses during treatment to reduce irritation.
  • Systemic absorption: use with caution in patients concurrently receiving systemic quinolones.
  • Pregnancy and lactation: safety not established; weigh benefits versus risks.
  • Store at room temperature below 25°C: keep in original container, protect from light and moisture.

Avoid Interactions

Levofloxacin may interact with other medications; some combinations require avoidance while others need monitoring.

Major Interactions (Avoid)

  • Systemic fluoroquinolones: concurrent use may increase risk of tendon toxicity.
  • Anticoagulants: may potentiate bleeding risk if systemic absorption occurs.

Moderate Interactions (Monitor Closely)

  • Corticosteroid eye drops: may mask signs of infection.
  • Non‑steroidal anti‑inflammatory eye drops: may increase ocular irritation.
  • Anticholinergic ophthalmic agents: may affect pupil response and accommodation.

Frequently Asked Questions

Levonics-Opto is a levofloxacin‑based ophthalmic solution indicated for the treatment of bacterial eye infections such as conjunctivitis, keratitis and corneal ulcers. It provides a topical antibacterial effect to eliminate pathogenic bacteria and promote healing of the ocular surface.

Levofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. By binding to these targets, the drug prevents bacterial DNA supercoiling and separation, leading to bactericidal activity against a broad spectrum of Gram‑positive and Gram‑negative ocular pathogens.

The dosing regimen for Levonic‑Opto is determined by the prescribing clinician based on the specific infection, severity and patient factors. The prescriber will specify the number of drops, frequency and duration of therapy in the prescription.

Safety of levofloxacin ophthalmic use during pregnancy or lactation has not been established. The potential benefits must be weighed against possible risks, and the decision should be made by a qualified healthcare professional in consultation with the patient.

To order Levonic‑Opto, submit an enquiry on the product page at gnhindia.com, providing the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then replies with pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Levonics‑Opto (levofloxacin) belongs to the fluoroquinolone class, offering broad‑spectrum coverage and high ocular penetration. Compared with older agents such as ciprofloxacin, levofloxacin provides a lower dosing frequency and may be more effective against resistant strains. Alternatives like moxifloxacin or fortified vancomycin are used for specific resistant organisms or severe infections.

Levonics‑Opto should be stored at room temperature below 25 °C, in its original packaging, protected from light and moisture. Do not freeze the product. Ensure the container is tightly closed when not in use to maintain sterility.

The product is applied as eye drops directly onto the affected eye(s). The prescribed number of drops is instilled at the recommended interval, typically without touching the tip of the bottle to the ocular surface. Patients should wash their hands before and after application.

Serious risks include severe allergic reactions (e.g., swelling, rash, Stevens‑Johnson syndrome), corneal edema, sudden loss of visual acuity, and rare systemic effects such as tendon toxicity if systemic absorption occurs. Patients should seek immediate medical attention if they experience intense pain, vision changes or signs of an allergic reaction.

Levonics‑Opto should be avoided in individuals with a known hypersensitivity to levofloxacin or any fluoroquinolone. Caution is also advised for patients with compromised corneal integrity, those using contact lenses during therapy, and patients receiving systemic quinolones due to increased risk of tendon-related adverse events.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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