Product image of Levonorgestrel Apofri (Levonorgestrel) supplied by GNH India

Levonorgestrel Apofri

Active Ingredient:
Levonorgestrel
Origin:
EU

Levonorgestrel Apofri (Levonorgestrel)

Levonorgestrel, the active ingredient in Levonorgestrel Apofri, is a synthetic progestin presented as an oral tablet for oral use. It is employed to prevent pregnancy either as emergency contraception or as part of a regular hormonal contraceptive regimen.
GNH India supplies Levonorgestrel Apofri as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Evolan Pharma Ab

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Indications & Clinical Uses

Levonorgestrel acts on the hormonal pathways that regulate ovulation and implantation.

  • Emergency contraception: prevents pregnancy when taken shortly after unprotected intercourse.
  • Regular contraception: provides ongoing hormonal birth control for women of reproductive age.
  • Ovulation suppression: inhibits the release of an egg during the menstrual cycle.

How It Works

  • Levonorgestrel binds to progesterone receptors in the hypothalamus and pituitary, suppressing the luteinizing hormone surge and thereby preventing ovulation. It also thickens cervical mucus, reducing sperm penetration, and induces endometrial changes that make implantation unlikely.

Side Effects

Levonorgestrel may cause a range of adverse reactions.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Headache: transient cranial discomfort.
  • Menstrual changes: spotting or altered flow.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, or breathing difficulty.
  • Chest pain or shortness of breath: possible thromboembolic event.
  • Liver dysfunction: jaundice or abnormal liver tests.

Precautions & Warnings

Before using Levonorgestrel Apofri, consider the following precautions.

  • Assess contraindications: review history of blood clots, liver disease, or hormone‑sensitive cancers.
  • Consider drug interactions: evaluate concurrent use of enzyme‑inducing medicines.
  • Monitor for adverse reactions: watch for signs of severe allergy or chest discomfort.
  • Use appropriate timing: follow recommended window for emergency use.
  • Store at ambient temperature: keep in the original pack, protect from moisture and light.

Avoid Interactions

Levonorgestrel can interact with several medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Rifampin: markedly reduces contraceptive effectiveness.
  • Anticonvulsants (phenytoin, carbamazepine): lower plasma levonorgestrel levels.
  • St. John's Wort: may decrease hormonal protection.

Moderate Interactions (Monitor Closely)

  • Azole antifungals (ketoconazole): can increase levonorgestrel concentrations.
  • Certain antibiotics (e.g., tetracycline): possible modest reduction in effect.
  • Estrogen‑containing hormonal therapies: may alter bleeding patterns.

Frequently Asked Questions

Levonorgestrel Apofri is used as a hormonal contraceptive. It can be taken as emergency contraception to prevent pregnancy after unprotected sex, or as a regular daily tablet for ongoing birth control in women of reproductive age.

Levonorgestrel works by binding to progesterone receptors, suppressing the luteinizing hormone surge that triggers ovulation. It also thickens cervical mucus, limiting sperm movement, and alters the uterine lining to make implantation unlikely.

The specific dose and regimen are determined by the prescribing healthcare professional. Levonorgestrel tablets are typically taken as a single dose for emergency use or as a daily tablet for regular contraception, according to the prescriber’s instructions.

Levonorgestrel is not intended for use during an established pregnancy and should be avoided by women who are already pregnant. Limited data exist for breastfeeding; healthcare providers usually weigh benefits against potential risks before prescribing.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levonorgestrel is a progestin‑only option, offering a single‑ingredient alternative to combined oral contraceptives that contain estrogen. It is effective for emergency use and for daily contraception without the estrogen‑related side‑effects, but it does not provide menstrual cycle regulation that some combined pills do.

Store the tablets at ambient temperature, below 25 °C, in the original packaging. Keep them away from moisture, direct sunlight and excessive heat to maintain product stability.

Levonorgestrel Apofri is taken orally. The tablet should be swallowed whole with water, following the timing instructions provided by the prescriber—either as a single dose for emergency contraception or once daily for regular use.

Serious risks include severe allergic reactions (rash, swelling, breathing difficulty), chest pain or shortness of breath that may signal a blood clot, and rare liver dysfunction. Any of these symptoms require immediate medical attention.

Women with a known history of thromboembolic disorders, severe liver disease, hormone‑sensitive cancers, or who are currently pregnant should avoid Levonorgestrel. Additionally, individuals with hypersensitivity to levonorgestrel or any tablet excipients should not take the product.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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