Product image of Levonorgestrel/Ethinylestradiol Biogarancontinu (Ethinylestradiol, Levonorgestrel | Lactose Anhydrous) supplied by GNH India

Levonorgestrel/Ethinylestradiol Biogarancontinu

Active Ingredient:
Ethinylestradiol, Levonorgestrel | Lactose Anhydrous
Origin:
EU

Levonorgestrel/Ethinylestradiol Biogarancontinu (Ethinylestradiol, Levonorgestrel | Lactose Anhydrous)

Ethinylestradiol / Levonorgestrel, the active ingredients in Levonorgestrel/Ethinylestradiol Biogarancontinu, are a combined oral contraceptive presented as a tablet for oral use. They prevent pregnancy in women of reproductive age.

GNH India supplies Levonorgestrel/Ethinylestradiol Biogarancontinu as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Biogaran

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Indications & Clinical Uses

Levonorgestrel/Ethinylestradiol is a combined oral contraceptive that acts on the hormonal regulation of the menstrual cycle.

  • Contraception: prevents pregnancy by inhibiting ovulation and altering cervical mucus.
  • Menstrual cycle regulation: helps achieve more predictable bleeding patterns.
  • Dysmenorrhea management: reduces menstrual pain and associated cramps.

How It Works

  • The combination of ethinylestradiol, a synthetic estrogen, and levonorgestrel, a progestogen, suppresses the hypothalamic‑pituitary‑ovarian axis, preventing the mid‑cycle surge of luteinising hormone and thus ovulation. It also thickens cervical mucus and induces endometrial changes that hinder sperm penetration and implantation.

Side Effects

Levonorgestrel/Ethinylestradiol may cause a range of adverse reactions.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Headache: tension‑type or migraine‑like.
  • Breast tenderness: temporary swelling or pain.
  • Spotting: irregular light bleeding between periods.
  • Weight change: slight increase or fluctuation.
  • Mood changes: irritability or mild depression.

Serious or Rare Side Effects

  • Venous thromboembolism: deep‑vein thrombosis or pulmonary embolism.
  • Hypertension: new‑onset or worsening high blood pressure.
  • Liver dysfunction: abnormal liver enzymes or jaundice.
  • Severe allergic reaction: rash, swelling, or anaphylaxis.
  • Gallbladder disease: gallstones or cholecystitis.
  • Visual disturbances: sudden loss of vision or eye pain.

Precautions & Warnings

Before using Levonorgestrel/Ethinylestradiol, consider the following safety measures.

  • Smoking: avoid if over 35 years old, as risk of cardiovascular events rises.
  • Cardiovascular disease: assess risk of stroke, myocardial infarction, or clotting disorders.
  • Liver disease: use with caution in patients with hepatic impairment.
  • Migraine with aura: contraindicated due to increased stroke risk.
  • Pregnancy testing: confirm non‑pregnant status before initiation.
  • Store at ambient temperature: keep below 25 °C, in the original packaging, protected from moisture and light.

Avoid Interactions

Levonorgestrel/Ethinylestradiol can interact with several medicines that affect hormone metabolism or clotting risk.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): may increase bleeding risk.
  • Certain antiretrovirals (e.g., efavirenz, nevirapine): can reduce contraceptive efficacy.
  • Rifampicin and other enzyme inducers: lower hormone levels, risking contraceptive failure.

Moderate Interactions (Monitor Closely)

  • Antidepressants (e.g., sertraline): may increase risk of mood changes.
  • Anticonvulsants (e.g., carbamazepine, phenytoin): may modestly decrease hormone concentrations.
  • Herbal supplements (e.g., St John's wort): potential reduction in effectiveness.

Frequently Asked Questions

Levonorgestrel/Ethinylestradiol Biogarancontinu is a combined oral contraceptive used to prevent pregnancy in women of reproductive age by inhibiting ovulation and creating an environment that is unfavorable for fertilisation and implantation.

Ethinylestradiol provides synthetic estrogen activity while levonorgestrel supplies progestogenic effects. Together they suppress the hypothalamic‑pituitary‑ovarian axis, preventing the luteinising hormone surge needed for ovulation, thicken cervical mucus, and alter the endometrium to reduce the chance of implantation.

The specific dosing regimen, including tablet strength and schedule, is determined by the prescribing clinician based on the product formulation and the individual patient's medical profile. Patients should follow the prescriber’s instructions exactly.

Levonorgestrel/Ethinylestradiol is intended for use in non‑pregnant women. It should not be started during pregnancy, and if pregnancy occurs, the product should be discontinued. Limited data exist for breastfeeding; clinicians usually advise caution and may recommend alternative contraception.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levonorgestrel/Ethinylestradiol combines a second‑generation progestogen with a low‑dose estrogen, offering a balance of contraceptive efficacy and a side‑effect profile comparable to other combined pills. Compared with newer formulations, it may have a slightly higher risk of estrogen‑related events but is widely used and well studied.

Store Levonorgestrel/Ethinylestradiol tablets at ambient temperature, preferably below 25 °C. Keep them in the original blister pack, protect from moisture, heat and direct sunlight to maintain potency throughout the shelf life.

The medication is taken orally, usually once daily at the same time each day, as a single tablet. Patients should swallow the tablet whole with water and not skip doses to maintain contraceptive effectiveness.

Serious risks include venous thromboembolism, arterial clotting events such as stroke or myocardial infarction, severe hypertension, and rare cases of liver dysfunction. Women with a history of clotting disorders, smoking over age 35, or certain cardiovascular conditions should avoid use.

Contraindications include women who are pregnant, have known or suspected breast cancer, active thromboembolic disease, uncontrolled hypertension, severe liver disease, or a history of migraine with aura. Smoking women over 35 years old should also avoid this product.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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