Product image of Levonorgestrel/Ethinylestradiol Cristers (Ethinylestradiol, Levonorgestrel) supplied by GNH India

Levonorgestrel/Ethinylestradiol Cristers

Active Ingredient:
Ethinylestradiol, Levonorgestrel
Origin:
EU

Levonorgestrel/Ethinylestradiol Cristers (Ethinylestradiol, Levonorgestrel)

Levonorgestrel/Ethinylestradiol, the active ingredient in Levonorgestrel/Ethinylestradiol Cristers, is a combined oral contraceptive presented as a tablet for oral use. It prevents pregnancy in women of reproductive age by inhibiting ovulation, thickening cervical mucus, and altering the endometrial lining.

GNH India supplies Levonorgestrel/Ethinylestradiol Cristers as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Cristers

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Levonorgestrel/Ethinylestradiol is a combined oral contraceptive used to prevent pregnancy by suppressing ovulation and altering cervical mucus.

  • Contraception: prevents unintended pregnancy in women of child‑bearing potential.
  • Menstrual cycle regulation: helps establish regular monthly bleeding patterns.
  • Management of dysmenorrhea: reduces menstrual pain and associated cramps.

How It Works

  • Levonorgestrel/Ethinylestradiol combines a synthetic progestogen (levonorgestrel) with an estrogen (ethinylestradiol). The estrogen stabilizes the endometrial lining while the progestogen suppresses the hypothalamic‑pituitary‑ovarian axis, preventing the mid‑cycle surge of luteinizing hormone that triggers ovulation. Additionally, the progestogen thickens cervical mucus, creating a barrier to sperm penetration, and the estrogen component modifies the endometrium to be less receptive to implantation.

Side Effects

Levonorgestrel/Ethinylestradiol may cause a range of adverse reactions. Most are mild and transient, but rare serious events can occur.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Headache: tension‑type or migraine‑like pain.
  • Breast tenderness: swelling or discomfort of the breasts.
  • Spotting: irregular light bleeding between periods.

Serious or Rare Side Effects

  • Deep vein thrombosis: blood clot formation in deep veins.
  • Pulmonary embolism: clot migration to lung vessels.
  • Stroke or myocardial infarction: vascular events linked to clotting risk.

Precautions & Warnings

Before prescribing Levonorgestrel/Ethinylestradiol, clinicians should consider several safety factors.

  • Cardiovascular risk assessment: avoid in women with a history of thromboembolic disorders.
  • Smoking status: contraindicated for smokers over 35 years of age.
  • Hepatic function: use with caution in patients with liver disease.
  • Drug interaction review: monitor concomitant use of enzyme‑inducing agents.
  • Store at room temperature: keep in the original packaging, protect from moisture and light.

Avoid Interactions

Levonorgestrel/Ethinylestradiol can interact with other medicines, affecting its effectiveness or safety.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., rifampin, carbamazepine): may markedly reduce contraceptive efficacy.
  • Certain antiepileptic drugs (e.g., phenytoin, phenobarbital): can lower hormone levels.

Moderate Interactions (Monitor Closely)

  • Antibiotics such as ampicillin: may slightly decrease effectiveness.
  • Antifungal agents like fluconazole: can increase hormone concentrations.
  • Herbal supplements (e.g., St. John’s wort): may diminish contraceptive reliability.

Frequently Asked Questions

Levonorgestrel/Ethinylestradiol Cristers is a combined oral contraceptive tablet prescribed to prevent pregnancy in women of reproductive age. It works by inhibiting ovulation, thickening cervical mucus, and altering the uterine lining to reduce the chance of fertilization and implantation.

The product contains levonorgestrel, a synthetic progestogen, and ethinylestradiol, a synthetic estrogen. Together they suppress the hypothalamic‑pituitary‑ovarian axis, preventing the luteinizing hormone surge that triggers ovulation, while also thickening cervical mucus and making the endometrium less suitable for implantation.

The specific dosing regimen for Levonorgestrel/Ethinylestradiol Cristers is determined by the prescribing clinician based on the product’s labeling and the patient’s medical profile. Patients should follow the prescriber’s instructions and not alter the dose on their own.

Levonorgestrel/Ethinylestradiol is intended to prevent pregnancy and should not be used by women who are already pregnant. Its safety during breastfeeding is not fully established; clinicians typically advise caution and may recommend alternative contraception for nursing mothers.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Levonorgestrel/Ethinylestradiol combines a second‑generation progestogen with a low‑dose estrogen, offering a balance of efficacy and tolerability. Compared with newer formulations that may use different progestogens or lower estrogen doses, it has a well‑characterized safety profile but may carry a slightly higher risk of estrogen‑related side effects.

Store the tablets at room temperature, preferably below 25 °C. Keep them in the original blister pack or container, protect from moisture and direct light, and discard any tablets that appear discolored or damaged.

Levonorgestrel/Ethinylestradiol Cristers are taken orally, usually once daily at the same time each day. The typical regimen involves a 21‑day active tablet phase followed by a 7‑day hormone‑free interval, during which withdrawal bleeding occurs.

Serious risks include thromboembolic events such as deep‑vein thrombosis, pulmonary embolism, stroke, and myocardial infarction. These events are rare but can be life‑threatening, especially in women with pre‑existing cardiovascular risk factors or who smoke heavily.

Women with a history of venous or arterial thromboembolism, uncontrolled hypertension, certain liver diseases, known or suspected breast cancer, or who are smokers over 35 years old should avoid this contraceptive. A thorough medical assessment is required before initiation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.