Product image of Levonorgestrel/Etinilestradiol Pensa (Ethinylestradiol, Levonorgestrel) supplied by GNH India

Levonorgestrel/Etinilestradiol Pensa

Active Ingredient:
Ethinylestradiol, Levonorgestrel
Origin:
EU

Levonorgestrel/Etinilestradiol Pensa (Ethinylestradiol, Levonorgestrel)

Ethinylestradiol, the active ingredient in Levonorgestrel/Etinilestradiol Pensa, is a combined estrogen‑progestogen oral contraceptive presented as an oral tablet for oral use. It works by suppressing ovulation and altering cervical mucus, providing reliable contraception when taken as prescribed.\n\nGNH India supplies Levonorgestrel/Etinilestradiol Pensa as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to EU quality standards and providing reliable global distribution.

Manufacturer / TM Owner

Towa Pharmaceutical S.A.

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Indications & Clinical Uses

  • Levonorgestrel/Etinilestradiol Pensa, a combined estrogen‑progestogen oral contraceptive, is used in the hormonal regulation of the menstrual cycle to prevent pregnancy.\n\n- Pregnancy prevention: provides reliable contraception when taken daily as directed.\n- Menstrual cycle regulation: helps establish a predictable menstrual pattern and reduces cycle irregularities.\n- Dysmenorrhea relief: lessens menstrual pain associated with primary dysmenorrhea.\n- Acne management: improves mild to moderate acne by reducing androgenic activity.

How It Works

  • Ethinylestradiol and levonorgestrel act together to inhibit the mid‑cycle surge of luteinizing hormone (LH) and follicle‑stimulating hormone (FSH), thereby suppressing ovulation. The estrogen component stabilises the endometrial lining, while the progestogen thickens cervical mucus and induces endometrial changes that make implantation unlikely.

Side Effects

  • Levonorgestrel/Etinilestradiol Pensa may be associated with a range of adverse reactions, which are generally categorized by frequency and severity.\n\nCommon Side Effects:\n- Nausea: mild to moderate stomach upset.\n- Headache: tension‑type or migraine‑like pain.\n- Breast tenderness: swelling or discomfort of the breasts.\n- Spotting or breakthrough bleeding: irregular light bleeding between periods.\n- Weight change: slight increase or decrease in body weight.\n- Mood changes: irritability or emotional fluctuations.\n\nSerious or Rare Side Effects:\n- Venous thromboembolism: deep‑vein thrombosis or pulmonary embolism.\n- Stroke: ischemic or hemorrhagic cerebrovascular event.\n- Myocardial infarction: heart attack due to reduced coronary flow.\n- Severe hypertension: sudden, dangerous rise in blood pressure.\n- Liver tumor: benign hepatic adenoma in rare cases.\n- Allergic reaction: rash, swelling, or anaphylaxis.

Precautions & Warnings

  • Before prescribing Levonorgestrel/Etinilestradiol Pensa, clinicians should consider several safety factors.\n- Contraindicated in women with a history of thromboembolic disorders: avoid use due to increased clot risk.\n- Avoid in smokers over 35 years: smoking adds cardiovascular risk.\n- Assess blood pressure before initiating therapy: monitor for hypertension.\n- Review liver function: hepatic disease may affect hormone metabolism.\n- Consider drug interactions with enzyme inducers: may reduce contraceptive efficacy.\n- Store at ambient temperature: keep below 25 °C, protect from moisture and light in the original packaging.

Avoid Interactions

  • Levonorgestrel/Etinilestradiol Pensa can interact with several medicines, influencing its effectiveness or safety.\n\nMajor Interactions (Avoid):\n- Enzyme‑inducing anticonvulsants (e.g., carbamazepine, phenytoin): may cause contraceptive failure.\n- Rifampin or rifabutin: reduces hormone levels, increasing risk of unintended pregnancy.\n- Protease inhibitors (e.g., ritonavir): can raise hormone concentrations, heightening side‑effect risk.\n\nModerate Interactions (Monitor Closely):\n- St. John’s wort: may lower contraceptive efficacy.\n- Certain antibiotics (e.g., griseofulvin): modestly reduce hormone levels.\n- Selective serotonin reuptake inhibitors: may increase incidence of mood changes.

Frequently Asked Questions

Levonorgestrel/Etinilestradiol Pensa is a combined estrogen‑progestogen oral contraceptive indicated primarily for the prevention of pregnancy in women of reproductive age. It may also be prescribed to help regulate menstrual cycles, reduce dysmenorrhea, and manage mild to moderate acne.

Ethinylestradiol, the estrogen component, stabilises the endometrial lining and works together with levonorgestrel to suppress the mid‑cycle surge of luteinizing hormone (LH) and follicle‑stimulating hormone (FSH). This inhibition prevents ovulation and, together with progestogen‑induced cervical mucus changes, reduces the chance of fertilisation and implantation.

The specific dosing regimen is determined by the prescribing healthcare professional based on the product’s labeling and the patient’s clinical needs. Typically, the medication is taken as one oral tablet daily, but the exact strength and schedule must be confirmed by the prescriber.

The product is contraindicated during pregnancy because it is intended to prevent conception, not to treat an existing pregnancy. While limited data exist for breastfeeding, caution is advised; healthcare providers usually assess the risk‑benefit ratio before recommending use in nursing mothers.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Levonorgestrel/Etinilestradiol Pensa contains the same hormone classes as most combined oral contraceptives, offering comparable efficacy in preventing pregnancy. Differences may lie in the specific estrogen‑to‑progestogen ratio, tablet size, or formulation additives, which can influence tolerability, bleeding patterns and individual side‑effect profiles.

Store the tablets at ambient temperature, preferably below 25 °C (77 °F). Keep them in the original blister pack or container, protect from moisture and direct light, and ensure they are out of reach of children.

The medication is taken orally with a glass of water, preferably at the same time each day. It should be swallowed whole and not chewed or broken. Consistent daily intake maximises contraceptive effectiveness.

Serious but rare risks include venous thromboembolism, pulmonary embolism, stroke, myocardial infarction, severe hypertension, and hepatic adenoma. Patients should seek immediate medical attention if they experience symptoms such as sudden chest pain, shortness of breath, severe headache, visual changes, or unexplained swelling of the legs.

Women with a known history of thromboembolic disease, uncontrolled hypertension, active liver disease, breast cancer, or who are pregnant should avoid this product. Additionally, smokers over the age of 35 and individuals taking interacting enzyme‑inducing drugs should not use it without medical guidance.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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