Product image of Levonorgestrel P Clydesdale Pharma (Levonorgestrel) supplied by GNH India

Levonorgestrel P Clydesdale Pharma

Active Ingredient:
Levonorgestrel
Origin:
EU

Levonorgestrel P Clydesdale Pharma (Levonorgestrel)

Levonorgestrel, the active ingredient in Levonorgestrel P Clydesdale Pharma, is a progestogen presented as an oral tablet for systemic use. It is employed to prevent pregnancy, both as an emergency contraceptive after unprotected intercourse and as a regular hormonal contraceptive for ongoing birth control.\n\nGNH India supplies Levonorgestrel P Clydesdale Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company follows stringent quality standards and offers reliable logistics to ensure consistent global distribution of the product.

Manufacturer / TM Owner

Clydesdale Pharma Limited

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Indications & Clinical Uses

  • Levonorgestrel is a progestogen used in hormonal contraceptive pathways to prevent pregnancy.\n\n- Emergency contraception: prevents pregnancy when taken within a defined time after unprotected sexual intercourse by inhibiting ovulation and altering the endometrium.\n- Regular hormonal contraception: provides ongoing birth control by suppressing ovulation and thickening cervical mucus to reduce sperm penetration.\n- Menstrual cycle regulation: can be used to delay or modify the timing of menstruation in women seeking cycle control.

How It Works

  • Levonorgestrel is a synthetic progestogen that binds to progesterone receptors in the hypothalamus and pituitary, suppressing the luteinizing hormone surge and thereby inhibiting ovulation. It also induces changes in the endometrial lining that reduce its receptivity to implantation and increases cervical mucus viscosity, creating a hostile environment for sperm. These combined actions ensure that fertilization and implantation are unlikely when the drug is administered at the appropriate time.

Side Effects

  • Levonorgestrel may cause a range of adverse reactions, varying from mild to severe.\n\nCommon Side Effects:\n- Nausea\n- Headache\n- Abdominal pain or cramps\n- Breast tenderness\n- Menstrual spotting or changes\n\nSerious or Rare Side Effects:\n- Thromboembolic events (deep vein thrombosis, pulmonary embolism)\n- Severe allergic reactions (anaphylaxis, angioedema)\n- Liver dysfunction or jaundice

Precautions & Warnings

  • When prescribing or dispensing levonorgestrel, several safety considerations should be observed.\n- Contraindication assessment: verify no known hypersensitivity to levonorgestrel or other progestins.\n- Medical review: ensure patient is not pregnant and has no active thromboembolic disorder.\n- Hepatic function: use with caution in patients with severe liver disease.\n- Drug interactions: review concomitant medications that may reduce efficacy, such as enzyme inducers.\n- Smoking status: advise against use in women over 35 who smoke heavily.\n- Store at below 25°C: keep tablets in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

  • Levonorgestrel can interact with other medicines, affecting its effectiveness or safety.\n\nMajor Interactions (Avoid):\n- Rifampin and other strong enzyme inducers: significantly reduce levonorgestrel plasma levels.\n- Antiepileptic drugs (carbamazepine, phenytoin, phenobarbital): may decrease contraceptive effectiveness.\n- St. John’s wort: herbal inducer that can lower drug exposure.\n\nModerate Interactions (Monitor Closely):\n- Antifungal agents (ketoconazole, itraconazole): may increase levonorgestrel levels, monitor for side effects.\n- Antibiotics (rifabutin, griseofulvin): may modestly affect efficacy, advise backup contraception.\n- Hormonal therapies (combined oral contraceptives, hormone replacement): assess cumulative hormonal load and adjust dosing if needed.

Frequently Asked Questions

Levonorgestrel P Clydesdale Pharma contains the synthetic progestogen levonorgestrel and is used to prevent pregnancy. It is indicated for emergency contraception after unprotected intercourse and as a regular hormonal method for ongoing birth control.

Levonorgestrel works by binding to progesterone receptors in the brain, suppressing the luteinizing hormone surge that triggers ovulation. It also thins the uterine lining and thickens cervical mucus, making it difficult for sperm to reach an egg and for implantation to occur.

The specific dose of levonorgestrel is determined by the prescribing healthcare professional based on the intended use, such as emergency contraception or a regular progestin‑only regimen. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Levonorgestrel is not intended for use during an established pregnancy and should be avoided unless specifically prescribed. Limited data are available for breastfeeding; while small amounts may pass into milk, clinicians usually weigh the benefits against potential risks before recommending use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Levonorgestrel is a progestogen‑only emergency contraceptive taken within 72 hours of unprotected sex, offering comparable efficacy to other levonorgestrel‑based products. It differs from copper‑IUD insertion, which can be effective up to five days, and from ulipristal acetate, which may retain higher efficacy closer to the 5‑day window.

Store Levonorgestrel tablets at temperatures below 25 °C in the original container, protected from moisture, heat and direct sunlight. Keep the product out of reach of children and avoid exposing it to excessive humidity, which could affect tablet integrity.

Levonorgestrel is administered orally as a tablet. For emergency contraception, a single dose (or a two‑dose regimen, depending on the product)

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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