Product image of Levonorgestrel Stada (Levonorgestrel) supplied by GNH India

Levonorgestrel Stada

Active Ingredient:
Levonorgestrel
Origin:
EU

Levonorgestrel Stada (Levonorgestrel)

Levonorgestrel, the active ingredient in Levonorgestrel Stada, is a progestin presented as an oral formulation for oral use. It is used for hormonal contraception, including emergency contraception, in women of reproductive age.

GNH India supplies Levonorgestrel Stada as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stada Arzneimittel Ag

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Indications & Clinical Uses

Levonorgestrel is a progestin used in hormonal contraception to prevent pregnancy.

  • Emergency contraception: provides post‑coital prevention of pregnancy when taken within the recommended time window.
  • Regular contraception: used in progestin‑only regimens to inhibit ovulation and thicken cervical mucus.
  • Menstrual cycle regulation: may be employed off‑label to manage irregular bleeding patterns.

How It Works

  • Levonorgestrel binds to progesterone receptors in the hypothalamus and pituitary, suppressing the luteinizing hormone surge and thereby inhibiting ovulation. It also induces changes in cervical mucus, making it less permeable to sperm, and alters the endometrium to reduce the likelihood of implantation.

Side Effects

Levonorgestrel is generally well tolerated, but a range of adverse reactions have been reported.

Common Side Effects

  • Nausea
  • Headache
  • Breast tenderness
  • Irregular vaginal bleeding
  • Mood changes
  • Abdominal pain

Serious or Rare Side Effects

  • Thromboembolic events (deep‑vein thrombosis, pulmonary embolism)
  • Severe allergic reaction (anaphylaxis)
  • Liver dysfunction or jaundice
  • Persistent high blood pressure
  • Ovarian cyst rupture (rare)

Precautions & Warnings

Before initiating Levonorgestrel therapy, several safety considerations should be reviewed.

  • Medical history review: assess for thromboembolic risk, liver disease, or hormone‑sensitive cancers.
  • Concurrent medication check: avoid use with enzyme‑inducing drugs that may reduce efficacy.
  • Pregnancy status: confirm the patient is not pregnant before starting.
  • Breastfeeding: evaluate benefits versus potential effects on the infant.
  • Smoking: advise cessation, especially in women over 35 years of age.
  • Store at ambient temperature: keep below 25°C, retain in the original packaging, and protect from moisture.

Avoid Interactions

Levonorgestrel may interact with other medicines, altering its effectiveness or safety profile.

Major Interactions (Avoid)

  • Enzyme inducers (e.g., rifampicin, carbamazepine): may markedly reduce contraceptive effectiveness.
  • Antifungal azoles (e.g., ketoconazole): can increase hormone levels, raising risk of side effects.
  • Protease inhibitor antiretrovirals: may alter hormone metabolism and affect efficacy.

Moderate Interactions (Monitor Closely)

  • Anticonvulsants (e.g., phenytoin): may modestly decrease contraceptive efficacy.
  • St. John’s wort: may reduce plasma concentrations of levonorgestrel.
  • Certain antibiotics (e.g., tetracycline): limited effect but monitor for breakthrough bleeding.

Frequently Asked Questions

Levonorgestrel Stada contains levonorgestrel, a progestin employed for hormonal contraception. It is indicated for emergency contraception to prevent pregnancy after unprotected intercourse and for regular, ongoing contraception as part of a progestin‑only regimen in women of reproductive age.

Levonorgestrel binds to progesterone receptors in the hypothalamus and pituitary, suppressing the luteinizing hormone surge that triggers ovulation. It also thickens cervical mucus, making it difficult for sperm to reach an egg, and induces endometrial changes that reduce the chance of implantation.

The specific dose and regimen of Levonorgestrel Stada are determined by the prescribing healthcare professional based on the indication, patient weight, timing of administration, and local regulatory guidance. Patients should follow the prescriber’s instructions and not alter the dose on their own.

Levonorgestrel Stada is intended for use in non‑pregnant individuals; it should not be started if pregnancy is already present. While limited data suggest minimal transfer into breast milk, the decision to use it while breastfeeding should be made by a healthcare provider weighing potential benefits against any theoretical risks to the infant.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements if applicable) and assists with import documentation.

Levonorgestrel Stada is a progestin‑only option, offering a smaller tablet size and no estrogen component, which can be advantageous for women who cannot tolerate estrogen. Compared with combined oral contraceptives, it has a slightly different side‑effect profile and may be less effective if taken later than the recommended window for emergency use.

Levonorgestrel Stada should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging to protect it from moisture and light. Do not store in bathrooms or near heat sources, and keep out of reach of children.

Levonorgestrel Stada is taken orally with a glass of water. For emergency contraception, it is usually taken as a single dose as soon as possible after unprotected intercourse, ideally within 72 hours. For regular contraception, the tablet is taken once daily at the same time each day, as directed by the prescriber.

Serious, though rare, risks include thromboembolic events such as deep‑vein thrombosis or pulmonary embolism, severe allergic reactions (anaphylaxis), and liver dysfunction. Patients should seek immediate medical attention if they experience unexplained chest pain, severe abdominal pain, swelling of the legs, or signs of an allergic reaction.

Levonorgestrel Stada is contraindicated in individuals who are pregnant, have a known hypersensitivity to levonorgestrel or any excipients, have active thromboembolic disease, hormone‑sensitive cancers (e.g., breast cancer), severe liver disease, or are smokers over 35 years old. A thorough medical assessment is required before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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