Levosert Shi (Levonorgestrel)

Levonorgestrel released from the intrauterine device binds to progesterone receptors in the endometrium, cervical mucus, and the hypothalamic‑pituitary axis. This suppresses ovulation, thickens cervical mucus, and creates endometrial changes that prevent implantation, thereby achieving contraception.

Levosert Shi is supplied as a pre‑loaded intrauterine system. The prescribing clinician determines the appropriate device based on the patient’s needs; the system continuously releases a low dose of levonorgestrel over its approved duration without the need for daily dosing.

Levosert Shi must not be inserted in a woman who is already pregnant, and it is contraindicated for use during pregnancy. For breastfeeding women, the device is generally considered compatible because systemic hormone levels are low, but clinicians should evaluate each case individually.

To order Levosert Shi, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levosert Shi uses levonorgestrel, similar to other hormonal IUDs such as Mirena or Kyleena. Its release rate and approved duration (up to three years) are comparable, but specific dosing and size may differ, offering clinicians flexibility based on patient anatomy and contraceptive preferences.

Levosert Shi should be stored at temperatures below 25 °C, in its original packaging, protected from moisture and direct sunlight. The device must be handled only by trained healthcare professionals during insertion and removal to maintain sterility and device integrity.

Levosert Shi is inserted by a qualified healthcare provider into the uterine cavity using a specialized inserter. The procedure is performed in a clinical setting, typically within the first five days of the menstrual cycle, and requires a brief pelvic examination and ultrasound confirmation of placement.

Serious risks, though rare, include uterine perforation during insertion, device expulsion or displacement, and pelvic inflammatory infection. Prompt recognition and management of these events are essential to maintain contraceptive efficacy and patient safety.

Levosert Shi is contraindicated in women who are pregnant, have active pelvic infection, unexplained vaginal bleeding, known or suspected uterine anomalies, or a history of uterine perforation. It should also be avoided in patients with hypersensitivity to levonorgestrel or any component of the device.