Product image of Levothyroxine Sodium 200 mcg/5ml Vials supplied by GNH India

Levothyroxine Sodium

Active Ingredient:
Levothyroxine Sodium
Form:
Vials
Brand:
Levothyroxine Sodium
Origin:
USA

Levothyroxine Sodium (Vials) 200 mcg/5ml

Levothyroxine sodium, the active ingredient in Levothyroxine Sodium, is a thyroid hormone presented as a 200 mcg/5ml injectable solution for intravenous use. It is used to replace or supplement thyroid hormone in patients who cannot reliably use oral therapy or require urgent intravenous treatment, such as those with severe hypothyroidism or myxedema coma.

GNH India supplies Levothyroxine Sodium as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

Strength

200 mcg/5ml

Pack Size

1s

Storage

Below 25°C

Manufacturer / TM Owner

Fresenius

1
Pack/s
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Indications & Clinical Uses

Levothyroxine Sodium is a thyroid hormone replacement therapy used to manage thyroid hormone deficiency. It is indicated for the following conditions:

  • Hypothyroidism: Replaces deficient thyroid hormone to restore normal metabolic activity.
  • Myxedema coma: Treats severe, life-threatening hypothyroidism when oral therapy is not feasible.
  • Thyroid hormone replacement after thyroidectomy: Supports patients who have undergone thyroid removal surgery.

How It Works

  • Levothyroxine sodium is a synthetic form of thyroxine (T4), which replaces deficient thyroid hormone in the body. Once administered, it circulates in the blood and is converted in body tissues to triiodothyronine (T3), the more active thyroid hormone. This process supports temperature regulation, metabolism, cardiovascular function, and mental status in patients with thyroid hormone deficiency.

Side Effects

Levothyroxine Sodium may cause side effects, although not everyone experiences them. Common Side Effects:

  • Headache
  • Nervousness
  • Tremors
  • Insomnia
  • Increased sweating
  • Weight loss
  • Diarrhea

Serious or Rare Side Effects

  • Allergic reactions, such as rash, itching, or swelling
  • Chest pain or irregular heartbeat
  • Severe headache or vision changes
  • Shortness of breath
  • Seizures
  • Fever or persistent sore throat

Precautions & Warnings

Levothyroxine Sodium should be used with caution and under medical supervision. Important precautions include:

  • Cardiovascular disease: Monitor closely in patients with heart conditions.
  • Adrenal insufficiency: Ensure adequate adrenal function before treatment.
  • Pregnancy: Use with caution, as thyroid hormone requirements may increase.
  • Elderly patients: Start with lower doses to avoid adverse effects.
  • Drug interactions: Consult with a healthcare provider before combining with other medications.
  • Store at controlled room temperature: Protect from light and do not freeze the vials unless specified in the package insert.

Avoid Interactions

Levothyroxine Sodium may interact with other medications, potentially altering its effectiveness or increasing the risk of side effects. Major Interactions (Avoid):

  • Antithyroid drugs: May counteract the effects of levothyroxine.
  • Cholestyramine: Can reduce the absorption of levothyroxine.
  • Iron supplements: May interfere with levothyroxine absorption.

Moderate Interactions (Monitor Closely)

  • Anticoagulants: May require dose adjustments to maintain therapeutic levels.
  • Antidepressants: May enhance the effects of levothyroxine.
  • Beta-blockers: May mask the symptoms of hyperthyroidism.

Frequently Asked Questions

Levothyroxine Sodium is used to replace or supplement thyroid hormone in patients with hypothyroidism, myxedema coma, or those who have undergone thyroidectomy. It helps restore normal metabolic activity and supports various physiological functions.

Levothyroxine sodium is a synthetic form of thyroxine (T4), which replaces deficient thyroid hormone in the body. Once administered, it circulates in the blood and is converted in body tissues to triiodothyronine (T3), the more active thyroid hormone, supporting temperature regulation, metabolism, cardiovascular function, and mental status.

The dosage of Levothyroxine Sodium is individualized and determined by a healthcare provider based on the patient's condition, age, and other factors. It typically involves a loading dose followed by a maintenance dose, with regular monitoring of thyroid hormone levels.

Levothyroxine Sodium is generally considered safe during pregnancy and breastfeeding, as thyroid hormone is essential for fetal and infant development. However, dosage adjustments may be necessary, and close monitoring by a healthcare provider is recommended.

To order Levothyroxine Sodium from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will then reply with pricing, availability, shipping, and the import paperwork.

Levothyroxine Sodium is a synthetic form of thyroxine (T4) and is one of the most commonly prescribed thyroid hormone replacement therapies. It is generally well-tolerated and effective for most patients. Other thyroid medications, such as liothyronine (T3), may be used in specific situations but are typically reserved for patients who do not respond adequately to levothyroxine.

Levothyroxine Sodium should be stored at controlled room temperature, protected from light, and kept in the original carton until use. Do not freeze the vials unless specified in the package insert. For transport, keep the vial in its carton with clear medication documentation and avoid placing it in checked luggage.

Levothyroxine Sodium is administered intravenously, typically in a clinical setting such as a hospital or clinic. It is used when oral thyroid tablets are not appropriate, such as in cases of severe hypothyroidism or myxedema coma. The medication is prepared and administered by healthcare professionals.

The most serious risks associated with Levothyroxine Sodium include allergic reactions, chest pain or irregular heartbeat, severe headache or vision changes, shortness of breath, seizures, and fever or persistent sore throat. Patients should seek immediate medical attention if they experience any of these symptoms.

Levothyroxine Sodium should not be used by individuals with untreated adrenal insufficiency, those with known hypersensitivity to levothyroxine or any of the excipients, and those with uncontrolled hyperthyroidism. Patients with cardiovascular disease or elderly patients should use it with caution and under close medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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