Product image of Levothyroxine Teva (Levothyroxine Sodium) supplied by GNH India

Levothyroxine Teva

Active Ingredient:
Levothyroxine Sodium
Origin:
EU

Levothyroxine Teva (Levothyroxine Sodium)

Levothyroxine, the active ingredient in Levothyroxine Teva, is a thyroid hormone presented as an oral formulation for oral use. It replaces deficient endogenous thyroid hormone and is used to treat hypothyroidism and related conditions.

GNH India supplies Levothyroxine Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Pharma B.V.

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Indications & Clinical Uses

Levothyroxine acts on the thyroid hormone pathway to restore normal metabolic function.

  • Hypothyroidism: normalises low thyroid hormone levels and alleviates associated symptoms.
  • Post‑thyroidectomy replacement: provides necessary hormone after surgical removal of the thyroid gland.
  • Goiter: reduces gland enlargement by correcting hormone deficiency.
  • Congenital hypothyroidism: supplies essential hormone to infants with absent or insufficient thyroid function.

How It Works

  • Levothyroxine is a synthetic form of thyroxine (T4) that is absorbed after oral administration and enters systemic circulation. It binds to nuclear thyroid hormone receptors in target cells, modulating gene transcription that controls basal metabolic rate, protein synthesis, and growth. By restoring circulating T4, it is converted to the active triiodothyronine (T3) within tissues, re‑establishing normal endocrine feedback and metabolic homeostasis.

Side Effects

Levothyroxine may cause a range of adverse reactions, most of which are dose‑related.

Common Side Effects

  • Headache: mild to moderate discomfort.
  • Insomnia: difficulty falling or staying asleep.
  • Palpitations: sensation of rapid or irregular heartbeat.
  • Weight loss: unintended reduction in body weight.
  • Heat intolerance: increased sensitivity to warm environments.
  • Tremor: fine shaking of hands or limbs.

Serious or Rare Side Effects

  • Cardiac arrhythmia: abnormal heart rhythm that may require medical attention.
  • Angina or chest pain: signs of myocardial ischemia.
  • Severe hyperthyroidism: symptoms such as anxiety, sweating, and rapid weight loss.
  • Allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Bone loss (osteoporosis): increased risk with long‑term overtreatment.
  • Myopathy: muscle weakness or pain.

Precautions & Warnings

When using Levothyroxine, several safety considerations should be observed.

  • Dose adjustment: monitor TSH and free T4 levels regularly to tailor therapy.
  • Cardiovascular disease: initiate therapy cautiously in patients with angina or arrhythmias.
  • Elderly patients: start with a lower dose and titrate slowly.
  • Pregnancy: discuss risks and benefits with a healthcare professional before use.
  • Drug interactions: review all concomitant medications for potential effects on absorption or metabolism.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Levothyroxine interacts with several medicines that can alter its absorption or effect.

Major Interactions (Avoid)

  • Calcium supplements: reduce levothyroxine absorption when taken simultaneously.
  • Iron salts: markedly decrease oral bioavailability.
  • Proton pump inhibitors: may lower absorption; separate dosing by at least 4 hours.
  • Antacids containing aluminum or magnesium: interfere with uptake.

Moderate Interactions (Monitor Closely)

  • Warfarin: levothyroxine may enhance anticoagulant effect; monitor INR.
  • SSRIs (e.g., sertraline): may require thyroid function monitoring.
  • Cholesterol‑lowering agents (e.g., cholestyramine): can bind levothyroxine and reduce its effectiveness.

Frequently Asked Questions

Levothyroxine Teva is prescribed to treat primary and secondary hypothyroidism, to replace thyroid hormone after thyroidectomy, to manage goiter caused by hormone deficiency, and to treat congenital hypothyroidism in newborns. It works by supplying the synthetic form of thyroxine (T4) that the body cannot produce in sufficient amounts.

Levothyroxine is a synthetic analogue of the natural thyroid hormone T4. After oral absorption, it circulates in the bloodstream, enters cells, and binds to nuclear thyroid hormone receptors. This binding regulates gene expression that controls metabolism, growth, and development, effectively restoring normal thyroid function in patients with deficiency.

The appropriate dose of Levothyroxine Teva is individualized by the prescribing clinician based on factors such as age, weight, severity of hormone deficiency, and laboratory thyroid function tests. Patients should follow the specific dosing instructions provided by their healthcare professional and have regular monitoring to ensure optimal therapy.

Levothyroxine is generally considered safe for use during pregnancy and lactation when prescribed by a qualified healthcare provider. Adequate thyroid hormone levels are essential for fetal development, and the drug may be continued with dose adjustments as needed. Patients should discuss any concerns with their physician before starting or altering therapy.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity of Levothyroxine Teva. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials. The team then provides pricing, availability, shipping details, and assists with any necessary import documentation.

Levothyroxine Teva is a generic formulation of levothyroxine sodium, comparable in efficacy and safety to brand‑name preparations such as Synthroid or Eltroxin. All contain the same active molecule and are bioequivalent when taken as directed. Differences may lie in excipients, packaging, or regulatory approvals, but therapeutic outcomes should be similar when dosing is appropriately managed.

Levothyroxine Teva should be stored at ambient temperature, preferably below 25 °C (77 °F). Keep the product in its original blister or bottle, protect it from moisture, excessive heat, and direct sunlight. Do not store in bathrooms or near kitchen appliances that generate steam or heat.

Levothyroxine Teva is taken orally, usually on an empty stomach, at least 30 minutes before breakfast or other medications. Swallow the tablet whole with a full glass of water; do not crush or chew unless the formulation specifically permits it. Consistent timing each day helps maintain stable hormone levels.

Serious risks include overtreatment leading to hyperthyroidism, which can cause cardiac arrhythmias, angina, or bone loss. Allergic reactions such as rash, swelling, or breathing difficulty are rare but require immediate medical attention. Regular monitoring of thyroid function tests helps mitigate these risks by allowing dose adjustments.

Levothyroxine Teva should be avoided in individuals with known hypersensitivity to levothyroxine sodium or any of the tablet’s excipients. Patients with untreated adrenal insufficiency or acute myocardial infarction should not initiate therapy until these conditions are stabilized. Always consult a healthcare professional before starting the medication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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