Product image of Levothyroxine Teva (Levothyroxine Sodium) supplied by GNH India

Levothyroxine Teva

Active Ingredient:
Levothyroxine Sodium
Origin:
EU

Levothyroxine Teva (Levothyroxine Sodium)

Levothyroxine Sodium, the active ingredient in Levothyroxine Teva, is a thyroid hormone presented as a tablet for oral use. It replaces or supplements endogenous thyroid hormone, treating hypothyroidism and related thyroid hormone deficiencies in both adults and children. It is indicated for patients with primary or secondary hypothyroidism, as well as for thyroid hormone replacement after thyroidectomy.

GNH India supplies Levothyroxine Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches for global distribution.

Manufacturer / TM Owner

Teva Italia S.R.L.

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Indications & Clinical Uses

Levothyroxine Teva is used to restore normal thyroid hormone levels in conditions affecting the hypothalamic‑pituitary‑thyroid axis.

  • Hypothyroidism: restores deficient thyroid hormone, normalizing metabolism and energy levels.
  • Post‑thyroidectomy hormone replacement: provides necessary thyroxine after surgical removal of the thyroid gland.
  • Congenital hypothyroidism: supplies thyroid hormone to infants born with insufficient gland function.
  • Goiter associated with hypothyroidism: reduces gland enlargement by correcting hormone deficiency.

How It Works

  • Levothyroxine Sodium is a synthetic analogue of the endogenous hormone thyroxine (T4). After oral absorption, it is converted to the active triiodothyronine (T3) within peripheral tissues. The hormone binds nuclear thyroid receptors, modulating gene transcription that regulates basal metabolic rate, protein synthesis, and growth. By restoring circulating T4 levels, the drug re‑establishes normal feedback to the hypothalamus and pituitary, normalizing thyroid‑stimulating hormone secretion.

Side Effects

Levothyroxine Teva may be associated with a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Headache
  • Fatigue
  • Weight loss
  • Tremor
  • Palpitations
  • Insomnia

Serious or Rare Side Effects

  • Cardiac arrhythmias
  • Angina pectoris
  • Hyperthyroidism symptoms (e.g., heat intolerance, anxiety)
  • Bone loss or fractures with long‑term overtreatment
  • Allergic reactions such as rash or angioedema
  • Severe chest pain

Precautions & Warnings

Before initiating Levothyroxine Teva, clinicians should consider several safety measures and monitoring requirements.

  • Dose adjustment: titrate based on serum TSH and free T4 levels.
  • Cardiovascular assessment: evaluate for ischemic heart disease before high‑dose therapy.
  • Pregnancy and lactation: use only if benefits outweigh potential risks; monitor thyroid function closely.
  • Elderly patients: start with lower doses to avoid overtreatment.
  • Drug interactions: review concomitant medications that may alter absorption or metabolism.
  • Store at ambient temperature: keep tablets in the original container, protect from moisture and light.

Avoid Interactions

Levothyroxine Teva can interact with several medicines, affecting its absorption or hormonal activity.

Major Interactions (Avoid)

  • Calcium or iron supplements taken within 4 hours: markedly reduce levothyroxine absorption.
  • Proton pump inhibitors (e.g., omeprazole): decrease gastric acidity, impairing absorption.
  • Anticonvulsants such as phenytoin or carbamazepine: increase metabolic clearance of levothyroxine.

Moderate Interactions (Monitor Closely)

  • Cholestyramine or colestipol: bind the drug and lower its bioavailability.
  • Warfarin: levothyroxine may enhance anticoagulant effect, requiring INR monitoring.
  • Beta‑blockers: may mask symptoms of excess thyroid hormone.

Frequently Asked Questions

Levothyroxine Teva is prescribed to treat hypothyroidism, to provide thyroid hormone replacement after thyroidectomy, to manage congenital hypothyroidism in newborns, and to help reduce goiter associated with thyroid hormone deficiency. It works by supplying synthetic thyroxine (T4) that the body can convert to the active hormone T3, thereby normalizing metabolic processes.

Levothyroxine sodium is a synthetic form of the natural thyroid hormone thyroxine (T4). After oral ingestion, it is absorbed into the bloodstream and converted in peripheral tissues to triiodothyronine (T3), the biologically active hormone. T3 binds to nuclear thyroid receptors, influencing gene expression that controls metabolism, growth, and development, effectively restoring normal thyroid function.

The appropriate dose of Levothyroxine Teva is individualized by the prescribing clinician based on factors such as the patient’s age, weight, severity of hypothyroidism, serum thyroid‑stimulating hormone (TSH) levels, and presence of cardiac disease. Dosage is typically adjusted after periodic laboratory monitoring to achieve target TSH ranges.

Levothyroxine is classified as a pregnancy‑category drug where the benefits generally outweigh potential risks when maternal hypothyroidism is present. Adequate thyroid hormone replacement is essential for fetal development. During breastfeeding, the drug is considered compatible, but thyroid function should be monitored closely in both mother and infant.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity of Levothyroxine Teva. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the team provides pricing, availability, shipping details, and any necessary import documentation.

Levothyroxine Teva is a generic formulation of levothyroxine sodium, comparable in potency and bioavailability to other branded or generic levothyroxine products that meet EU pharmacopeial standards. Differences among products may arise from excipients, tablet dissolution characteristics, or manufacturing processes, but clinical efficacy and safety are expected to be equivalent when dosed appropriately.

Levothyroxine Teva tablets should be stored at ambient temperature, preferably below 25 °C, in the original blister pack or container. Protect them from excess moisture, heat, and direct sunlight to maintain potency throughout the shelf life.

Levothyroxine Teva is taken orally, usually on an empty stomach at least 30 minutes before breakfast or other medications. The tablet should be swallowed whole with a glass of water; it should not be crushed, chewed, or divided unless specifically instructed by a healthcare professional.

Serious risks include cardiac arrhythmias, angina, or myocardial infarction, especially in patients with pre‑existing heart disease, as well as symptoms of overt hyperthyroidism such as severe tremor, heat intolerance, and anxiety. Long‑term overtreatment can lead to bone loss or fractures. Any signs of allergic reaction, such as rash or swelling, should prompt immediate medical attention.

Levothyroxine Teva should be avoided in individuals with known hypersensitivity to levothyroxine sodium or any of the tablet’s excipients. Patients with untreated adrenal insufficiency, uncorrected thyrotoxicosis, or acute myocardial infarction should not receive the drug until these conditions are managed.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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