Product image of Levothyroxinenatrium Teva (Levothyroxine Sodium) supplied by GNH India

Levothyroxinenatrium Teva

Active Ingredient:
Levothyroxine Sodium
Origin:
EU

Levothyroxinenatrium Teva (Levothyroxine Sodium)

Levothyroxine sodium, the active ingredient in Levothyroxinenatrium Teva, is a thyroid hormone presented as an oral tablet for oral use. It treats hypothyroidism and related thyroid hormone deficiencies in adults and children.\n\nGNH India supplies Levothyroxinenatrium Teva as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Nederland B.V.

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Indications & Clinical Uses

  • Levothyroxinenatrium Teva is a synthetic thyroid hormone used to restore normal hormone levels in conditions affecting the thyroid axis.\n\n- Hypothyroidism: restores normal thyroid hormone concentrations, improving metabolism and energy levels.\n- Goiter: reduces TSH stimulation, helping to decrease thyroid gland size.\n- Post‑thyroidectomy replacement: provides necessary hormone to maintain metabolic function after surgical removal of the thyroid.\n- Congenital hypothyroidism: supports growth and neurodevelopment in infants with deficient thyroid function.

How It Works

  • Levothyroxine sodium is a synthetic form of the endogenous hormone thyroxine (T4). After oral absorption, it is converted to the active hormone triiodothyronine (T3) in peripheral tissues. The hormone binds nuclear thyroid receptors, modulating gene transcription that regulates basal metabolic rate, protein synthesis, and growth. By restoring normal circulating thyroid hormone levels, it normalizes the hypothalamic‑pituitary‑thyroid feedback loop.

Side Effects

  • Levothyroxinenatrium Teva may cause a range of adverse reactions, most of which are dose‑related and reversible upon dose adjustment.\n\nCommon Side Effects:\n- Headache\n- Insomnia\n- Palpitations\n- Heat intolerance\n- Tremor\n- Weight loss\n\nSerious or Rare Side Effects:\n- Allergic reaction (rash, angioedema)\n- Chest pain or angina\n- Cardiac arrhythmia\n- Severe bone loss (osteoporosis)\n- Thyrotoxic crisis (excessive hyperthyroidism)

Precautions & Warnings

  • Levothyroxinenatrium Teva requires careful monitoring and individualized dosing to avoid over‑ or under‑replacement.\n\n- Dose adjustment: monitor TSH and free T4 levels regularly and titrate dose accordingly.\n- Cardiovascular disease: use caution as excess hormone may provoke tachycardia or angina.\n- Pregnancy: discuss risk‑benefit with a physician; thyroid hormone is essential for fetal development.\n- Elderly patients: initiate therapy at lower doses and increase slowly.\n- Drug interactions: review all concomitant medications for potential absorption or metabolic effects.\n- Store at ambient temperature: keep below 25°C, protect from moisture and light, retain in original container.

Avoid Interactions

  • Levothyroxinenatrium Teva can interact with several medicines that affect its absorption or pharmacodynamic profile.\n\nMajor Interactions (Avoid):\n- Antacids containing aluminum or magnesium: significantly reduce levothyroxine absorption.\n- Warfarin: levothyroxine may enhance anticoagulant effect, requiring INR monitoring.\n- Insulin or oral hypoglycemics: increased hormone levels can potentiate hypoglycemia.\n\nModerate Interactions (Monitor Closely):\n- Cholestyramine, colestipol, or other bile‑acid sequestrants: may decrease levothyroxine bioavailability.\n- Estrogen therapy or oral contraceptives: may increase levothyroxine requirement.\n- Selective serotonin reuptake inhibitors (SSRIs): can alter thyroid hormone metabolism, necessitating periodic TSH checks.

Frequently Asked Questions

Levothyroxinenatrium Teva contains levothyroxine sodium, a synthetic thyroid hormone prescribed to treat hypothyroidism, manage goiter, and provide hormone replacement after thyroidectomy or in congenital deficiency. It restores normal thyroid hormone levels, supporting metabolism, growth, and overall physiological balance.

Levothyroxine sodium is absorbed from the gastrointestinal tract and converted to the active hormone triiodothyronine (T3) in peripheral tissues. T3 binds nuclear thyroid receptors, influencing gene transcription that regulates basal metabolic rate, protein synthesis, and growth, thereby correcting the hormonal deficit present in thyroid disorders.

The appropriate dose of Levothyroxinenatrium Teva is individualized and determined by the prescribing clinician based on factors such as age, weight, severity of hormone deficiency, and laboratory values (TSH, free T4). Patients should follow the prescriber’s instructions and have thyroid function monitored regularly.

Levothyroxine is generally considered safe in pregnancy and lactation when used at the dose required to maintain normal maternal thyroid function, as untreated hypothyroidism can harm fetal development. However, therapy should be guided by a healthcare professional who will weigh benefits and potential risks.

To order Levothyroxinenatrium Teva, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Levothyroxinenatrium Teva provides levothyroxine sodium, the standard synthetic form of T4 used globally. Compared with combination T4/T3 preparations, it offers a stable, predictable pharmacokinetic profile and is the most widely studied option for thyroid hormone replacement, making it a first‑line choice in most treatment guidelines.

Levothyroxinenatrium Teva should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct light, and avoid storing it in bathrooms or near heat sources to maintain potency.

Levothyroxinenatrium Teva is taken orally, usually once daily on an empty stomach, at least 30 minutes before breakfast. The tablet should be swallowed whole with a full glass of water; it should not be crushed, chewed, or divided unless specifically instructed by a healthcare professional.

Serious risks include excessive thyroid hormone levels leading to symptoms of hyperthyroidism such as cardiac arrhythmias, angina, or a thyrotoxic crisis, as well as allergic reactions like rash or angioedema. Patients should seek immediate medical attention if they experience chest pain, rapid heartbeat, severe tremor, or signs of an allergic response.

Levothyroxinenatrium Teva is contraindicated in individuals with known hypersensitivity to levothyroxine sodium or any of the tablet excipients. Patients with untreated adrenal insufficiency, acute myocardial infarction, or uncorrected thyrotoxicosis should not receive the medication until these conditions are appropriately managed.

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GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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