Product image of Levotiroxina (Levothyroxine Sodium) supplied by GNH India

Levotiroxina

Active Ingredient:
Levothyroxine Sodium
Origin:
EU

Levotiroxina (Levothyroxine Sodium)

Levothyroxine Sodium, the active ingredient in Levotiroxina, is a thyroid hormone presented as an oral tablet for oral use. It is used to treat hypothyroidism, replace thyroid hormone after thyroidectomy, and manage goiter in patients requiring hormone supplementation.

GNH India supplies Levotiroxina as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Italia S.R.L.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Levotiroxina is a synthetic thyroid hormone used to restore normal metabolic function in disorders of thyroid hormone deficiency.

  • Hypothyroidism: normalizes low thyroid hormone levels and alleviates related symptoms.
  • Post‑thyroidectomy hormone replacement: provides the missing thyroxine after surgical removal of the thyroid gland.
  • Goiter: reduces gland enlargement by supplying adequate hormone feedback.

How It Works

  • Levothyroxine Sodium is a synthetic form of thyroxine (T4) that is absorbed after oral administration and converted in peripheral tissues to the active hormone triiodothyronine (T3). Both T4 and T3 bind to nuclear thyroid hormone receptors, modulating gene transcription that increases basal metabolic rate and regulates growth, development, and metabolism throughout the body.

Side Effects

Levotiroxina may cause a range of adverse reactions, most of which are dose‑related and reversible upon adjustment.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Palpitations: sensation of rapid or irregular heartbeat.
  • Tremor: fine shaking of hands or limbs.
  • Insomnia: difficulty falling or staying asleep.
  • Weight loss: unintended reduction in body weight.
  • Gastrointestinal upset: nausea, vomiting, or abdominal discomfort.

Serious or Rare Side Effects

  • Cardiac arrhythmia: potentially life‑threatening irregular heart rhythm.
  • Angina or myocardial ischemia: chest pain due to reduced heart blood flow.
  • Osteoporosis: decreased bone mineral density with long‑term excess.
  • Hyperthyroid symptoms: heat intolerance, sweating, anxiety.
  • Allergic reaction: rash, itching, swelling, or anaphylaxis.
  • Severe muscle weakness: myopathy or rhabdomyolysis.

Precautions & Warnings

Before initiating Levotiroxina therapy, consider patient‑specific factors and monitor appropriately.

  • Cardiovascular disease: assess heart status, especially in elderly patients.
  • Diabetes mellitus: monitor blood glucose as thyroid hormone can affect glycemic control.
  • Pregnancy and lactation: use only if clearly needed; discuss risks with a healthcare provider.
  • Elderly patients: start with lower doses and titrate cautiously.
  • Drug interactions: review concomitant medications that may alter absorption or effect.
  • Store at ambient temperature: keep below 25 °C, retain in original container, protect from moisture and direct sunlight.

Avoid Interactions

Levotiroxina absorption and activity can be altered by several co‑administered agents.

Major Interactions (Avoid)

  • Calcium supplements: bind levothyroxine and reduce its absorption.
  • Iron salts: significantly decrease oral bioavailability when taken together.
  • Antacids containing aluminum or magnesium: impair absorption if taken within 4 hours.
  • Cholestyramine or colestipol: sequester the drug and lower systemic exposure.
  • Sucralfate: forms complexes that limit absorption.

Moderate Interactions (Monitor Closely)

  • Warfarin: thyroid hormone may enhance anticoagulant effect; monitor INR.
  • Diabetes medications: levothyroxine can increase insulin requirements.
  • Antidepressants (SSRIs, TCAs): may require dose adjustments due to metabolic changes.
  • Estrogen therapy: may increase levothyroxine binding, necessitating dose review.

Frequently Asked Questions

Levotiroxina is prescribed for hypothyroidism, to replace thyroid hormone after thyroidectomy, and to manage goiter. In each case, it supplies the missing thyroxine (T4) that the body cannot produce sufficiently on its own.

Levothyroxine Sodium is a synthetic form of the natural hormone T4. After oral absorption, it is converted to the active hormone T3 in peripheral tissues. Both T4 and T3 bind to nuclear thyroid receptors, regulating gene expression that controls metabolism, growth, and development.

The appropriate dose of Levotiroxina is individualized. A qualified prescriber determines the exact amount based on the patient’s age, weight, thyroid function tests, and clinical response. Dosage adjustments are made during follow‑up visits.

Levotiroxina may be used during pregnancy and lactation when clearly indicated, as untreated hypothyroidism poses greater risks. The prescriber will weigh benefits against potential risks and monitor thyroid function closely throughout gestation and nursing.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Levotiroxina is the standard synthetic T4 replacement and is generally preferred for its predictable pharmacokinetics and ease of monitoring. Alternatives such as liothyronine (synthetic T3) or desiccated thyroid extract may be used in specific cases, but they often require more frequent dosing and careful titration.

Store Levotiroxina tablets at ambient temperature, below 25 °C. Keep the product in its original packaging, protect it from moisture, heat, and direct sunlight to maintain potency throughout its shelf life.

Levotiroxina is taken orally, usually on an empty stomach 30–60 minutes before breakfast. Swallow the tablet whole with a full glass of water; do not crush or chew it, as this can affect absorption.

Serious risks include cardiac arrhythmias, angina, myocardial ischemia, severe osteoporosis with long‑term excess, and hyperthyroid symptoms such as heat intolerance and anxiety. Patients should report chest pain, rapid heartbeat, or unexplained bone pain to their healthcare provider promptly.

Levotiroxina is contraindicated in patients with untreated adrenal insufficiency, acute myocardial infarction, or uncorrected thyrotoxicosis. Individuals with known hypersensitivity to levothyroxine or any excipients in the tablet should also avoid its use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Levothyroxine Sodium

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT