Product image of Lexapro (Escitalopram Oxalate) supplied by GNH India

Lexapro

Active Ingredient:
Escitalopram Oxalate
Origin:
EU

Lexapro (Escitalopram Oxalate)

Escitalopram, the active ingredient in Lexapro, is a selective serotonin reuptake inhibitor (SSRI) presented as a tablet for oral use. It treats major depressive disorder and generalized anxiety disorder in adults.

GNH India supplies Lexapro as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

H. Lundbeck A/S

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Indications & Clinical Uses

Lexapro (escitalopram) is an SSRI indicated for the following conditions:

  • Major depressive disorder: reduces depressive symptoms and improves overall mood.
  • Generalized anxiety disorder: alleviates excessive worry and promotes functional improvement.
  • Panic disorder: decreases the frequency and severity of panic attacks.

How It Works

  • Escitalopram selectively inhibits the serotonin transporter (SERT) on presynaptic neurons, blocking reuptake of serotonin from the synaptic cleft. This increases extracellular serotonin concentrations, enhancing serotonergic neurotransmission and contributing to mood stabilization and anxiety reduction.

Side Effects

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Headache: tension‑type or throbbing pain.
  • Insomnia: difficulty falling or staying asleep.
  • Dry mouth: reduced salivation.
  • Sexual dysfunction: decreased libido or delayed orgasm.
  • Dizziness: light‑headed sensation.

Serious or Rare Side Effects

  • Serotonin syndrome: agitation, hyperthermia, muscle rigidity.
  • Suicidal thoughts: emergence of new or worsening ideation.
  • Severe allergic reaction: rash, swelling, breathing difficulty.
  • QT interval prolongation: cardiac rhythm disturbance.
  • Abnormal bleeding: easy bruising or prolonged clotting.
  • Hyponatremia: low blood sodium causing confusion or seizures.

Precautions & Warnings

Before initiating therapy, consider the following precautions:

  • Assess for suicidal ideation: monitor mood changes, especially early in treatment.
  • Monitor for serotonin syndrome: avoid concurrent serotonergic agents.
  • Caution in hepatic impairment: dose adjustment may be required.
  • Avoid abrupt discontinuation: taper under medical supervision to reduce withdrawal.
  • Use with caution in pregnancy: evaluate risk‑benefit with a healthcare professional.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Escitalopram may interact with other medicines. Review the following groups:

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): risk of severe serotonin syndrome.
  • Pimozide: can cause cardiac arrhythmias.
  • Thioridazine: may lead to QT prolongation.

Moderate Interactions (Monitor Closely)

  • NSAIDs or anticoagulants: increased bleeding risk.
  • Other serotonergic agents (e.g., triptans, tramadol): may elevate serotonin levels.
  • Carbamazepine: may reduce escitalopram plasma concentrations.

Frequently Asked Questions

Lexapro (escitalopram) is prescribed for major depressive disorder and generalized anxiety disorder in adults. In some regions it is also approved for panic disorder, helping to reduce the frequency and intensity of panic attacks.

Escitalopram blocks the serotonin transporter, preventing reuptake of serotonin into presynaptic neurons. This raises serotonin levels in the synaptic cleft, enhancing serotonergic signaling, which is associated with improved mood and reduced anxiety.

The specific dose of Lexapro is determined by the prescribing clinician based on the individual’s condition, response, and tolerability. Patients should follow the dosage instructions provided by their healthcare professional.

Safety of escitalopram during pregnancy or lactation has not been definitively established. Healthcare providers weigh potential benefits against possible risks and may consider alternative treatments if concerns arise.

To request Lexapro, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lexapro is a highly selective SSRI, offering a favorable side‑effect profile compared with less selective SSRIs and older antidepressants such as tricyclics. Its potency often allows lower dosing, but individual response varies, so clinicians choose based on efficacy, tolerability and patient history.

Lexapro tablets should be stored at room temperature, below 25 °C, in the original packaging. Keep them away from moisture, heat and direct sunlight to maintain product stability.

Lexapro is taken orally, usually once daily with or without food. The tablet should be swallowed whole with water and not crushed or chewed unless directed by a healthcare professional.

Serious risks include the potential for serotonin syndrome, emergence of suicidal thoughts or behaviors, severe allergic reactions, QT interval prolongation, and hyponatremia. Patients should seek immediate medical attention if they experience any of these symptoms.

Lexapro is contraindicated in individuals who have taken a monoamine oxidase inhibitor within the past 14 days, those with known hypersensitivity to escitalopram or any tablet components, and patients with certain cardiac conditions that predispose them to QT prolongation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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