Product image of Lexapro (Escitalopram Oxalate) supplied by GNH India

Lexapro

Active Ingredient:
Escitalopram Oxalate
Origin:
EU

Lexapro (Escitalopram Oxalate)

Escitalopram, the active ingredient in Lexapro, is a selective serotonin reuptake inhibitor (SSRI) presented as an oral tablet for oral administration. It is used to treat major depressive disorder and generalized anxiety disorder, helping to improve mood and reduce anxiety symptoms in adult patients.

GNH India supplies Lexapro as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing for regulated markets. The company adheres to stringent quality standards and offers comprehensive logistics support for global distribution.

Manufacturer / TM Owner

H. Lundbeck A/S

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Indications & Clinical Uses

Lexapro (escitalopram) acts on the serotonergic system and is indicated for the following conditions:

  • Major depressive disorder: reduces depressive symptoms and improves overall mood.
  • Generalized anxiety disorder: alleviates excessive worry and anxiety.
  • Major depressive disorder (maintenance therapy): helps prevent relapse after remission.

How It Works

  • Escitalopram selectively inhibits the serotonin transporter (SERT) on presynaptic neurons, blocking reuptake of serotonin into the nerve terminal. This increases extracellular serotonin concentrations in the central nervous system, enhancing serotonergic neurotransmission and contributing to mood stabilization and anxiolytic effects.

Side Effects

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Headache: transient tension‑type headaches.
  • Insomnia: difficulty falling or staying asleep.
  • Dry mouth: reduced salivation.
  • Sexual dysfunction: decreased libido or delayed orgasm.
  • Dizziness: light‑headed sensation, especially on standing.

Serious or Rare Side Effects

  • Serotonin syndrome: agitation, hyperthermia, muscle rigidity.
  • Suicidal thoughts: emergence of suicidal ideation, particularly in young adults.
  • Severe allergic reaction: rash, swelling, or anaphylaxis.
  • QT interval prolongation: cardiac rhythm disturbances.
  • Mania or hypomania: sudden mood elevation in susceptible individuals.
  • Hyponatremia: low blood sodium, especially in elderly patients.

Precautions & Warnings

Precautions should be observed when prescribing or dispensing Lexapro:

  • Assess for suicidal ideation: monitor patients closely during initiation and dose changes.
  • Avoid use in patients with known hypersensitivity to escitalopram or other SSRIs.
  • Caution in hepatic impairment: dose adjustment may be required.
  • Consider drug interactions: review concomitant serotonergic agents and other medications.
  • Store at ambient temperature below 25°C: keep in the original container, protect from moisture and light.

Avoid Interactions

Lexapro may interact with other medicines; careful review is essential.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): risk of serotonin syndrome.
  • Pimozide: increased risk of QT prolongation.
  • Thioridazine: potential for cardiac arrhythmias.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): heightened bleeding risk.
  • Anticoagulants (e.g., warfarin): may enhance anticoagulant effect.
  • Other serotonergic agents (e.g., tramadol, triptans): monitor for serotonin syndrome.
  • Carbamazepine: may reduce escitalopram plasma levels.
  • Alcohol: can increase CNS depression and impair judgment.

Frequently Asked Questions

Lexapro (escitalopram) is prescribed for major depressive disorder and generalized anxiety disorder in adult patients. It helps alleviate depressive symptoms, improve mood, and reduce excessive worry and anxiety associated with these conditions.

Escitalopram selectively blocks the serotonin transporter, preventing reuptake of serotonin into presynaptic neurons. This raises serotonin levels in the synaptic cleft, enhancing serotonergic neurotransmission, which is linked to mood regulation and anxiety reduction.

The appropriate dose of Lexapro is determined by the prescribing clinician based on the individual’s medical condition, response to therapy, and tolerability. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety of escitalopram during pregnancy or lactation has not been definitively established. Healthcare providers weigh potential benefits against risks and may consider alternative treatments. Patients should discuss any concerns with their prescriber before use.

To request Lexapro, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and necessary import documentation.

Lexapro is a highly selective SSRI, offering a favorable side‑effect profile compared with less selective SSRIs and older antidepressant classes such as tricyclics or monoamine oxidase inhibitors. Its potency often allows effective symptom control at lower doses, but individual response varies.

Lexapro tablets should be stored at ambient temperature below 25 °C, in the original packaging, protected from moisture, heat, and direct light. Keep the product out of reach of children and do not use after the expiration date.

Lexapro is taken orally, usually once daily, with or without food. The tablet should be swallowed whole with a glass of water. Patients should follow the dosing schedule prescribed by their healthcare professional.

Serious risks include the potential for serotonin syndrome, emergence of suicidal thoughts or behaviors, severe allergic reactions, QT interval prolongation, and hyponatremia. Any concerning symptoms should prompt immediate medical evaluation.

Lexapro is contraindicated in individuals with known hypersensitivity to escitalopram or other SSRIs, and in patients currently taking monoamine oxidase inhibitors. Caution is advised for those with severe hepatic impairment, certain cardiac conditions, or a history of mania.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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