Product image of Lexaurin (Bromazepam) supplied by GNH India

Lexaurin

Active Ingredient:
Bromazepam
Origin:
EU

Lexaurin (Bromazepam)

Bromazepam, the active ingredient in Lexaurin, is a benzodiazepine presented as an oral tablet for oral use. It is prescribed for anxiety disorders and provides short‑term relief of anxiety in adult patients and may be used in clinical settings requiring rapid anxiolysis under medical supervision.

GNH India supplies Lexaurin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation to support import and distribution. Customers benefit from reliable logistics and responsive technical support throughout the supply chain.

Manufacturer / TM Owner

Krka, D.D., Novo Mesto

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Indications & Clinical Uses

Bromazepam acts on the central nervous system to alleviate anxiety-related conditions.

  • Anxiety disorders: reduces excessive worry and tension, improving daily functioning.
  • Short‑term relief of anxiety: provides rapid symptom control during acute episodes.
  • Preoperative anxiety: calms patients before surgical procedures, facilitating cooperation.
  • Panic attacks (acute): may be employed for short‑term management of isolated panic episodes.
  • Adjustment disorder with anxiety: helps mitigate heightened stress responses during life changes.

How It Works

  • Bromazepam binds to the benzodiazepine site on the γ‑aminobutyric acid type A (GABA‑A) receptor complex, acting as a positive allosteric modulator. This interaction increases the frequency of chloride channel opening in response to GABA, enhancing inhibitory neurotransmission and producing a calming effect on neuronal activity throughout the brain. The potentiated GABAergic inhibition reduces neuronal firing in limbic structures that mediate fear and stress, contributing to its anxiolytic properties.

Side Effects

Bromazepam may be associated with a range of adverse reactions, varying in frequency and severity.

Common Side Effects

  • Drowsiness
  • Fatigue
  • Dizziness
  • Impaired coordination

Serious or Rare Side Effects

  • Respiratory depression
  • Severe allergic reaction (e.g., rash, swelling, anaphylaxis)

Precautions & Warnings

When prescribing bromazepam, clinicians should consider several safety measures to minimize risk.

  • Assess renal and hepatic function: adjust use in patients with severe impairment.
  • Avoid abrupt discontinuation: taper under medical supervision to prevent withdrawal.
  • Monitor for signs of dependence: use only short term and reassess regularly.
  • Caution in elderly: increased sensitivity to sedation and falls.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Bromazepam can interact with other substances that affect the central nervous system or drug metabolism.

Major Interactions (Avoid)

  • Alcohol: additive CNS depression leading to profound sedation.
  • Opioids: combined effect may cause respiratory depression.
  • Other benzodiazepines: cumulative sedation and increased overdose risk.

Moderate Interactions (Monitor Closely)

  • Selective serotonin reuptake inhibitors (SSRIs): may enhance sedative effect.
  • Antihistamines: can increase drowsiness and impair alertness.

Frequently Asked Questions

Lexaurin contains bromazepam, a benzodiazepine indicated for the management of anxiety disorders and for short‑term relief of anxiety symptoms. It is commonly prescribed to adults who need rapid anxiolysis, such as before medical procedures or during acute stress episodes.

Bromazepam binds to the benzodiazepine site on the GABA‑A receptor complex, acting as a positive allosteric modulator. This enhances the effect of the inhibitory neurotransmitter GABA, increasing chloride ion influx, which dampens neuronal excitability and produces a calming, anxiolytic effect.

The appropriate dose of Lexaurin is determined by the prescribing clinician based on the patient’s age, clinical condition, and response to therapy. Dosage may be adjusted for renal or hepatic impairment, and treatment duration is generally limited to the shortest period necessary to control symptoms.

Bromazepam is generally not recommended during pregnancy or lactation because it can cross the placenta and appear in breast milk, potentially affecting the fetus or infant. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss alternative treatments with their healthcare provider.

To request Lexaurin, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will verify trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Lexaurin (bromazepam) shares the core anxiolytic mechanism of other benzodiazepines such as diazepam or lorazepam but differs in potency, half‑life and metabolic profile. Bromazepam is considered intermediate‑acting, offering effective anxiety control with a lower risk of accumulation compared with longer‑acting agents.

Lexaurin tablets should be stored at ambient temperature, below 25 °C, in the original container to protect them from moisture and direct light. Keep the product out of reach of children and avoid storing in bathrooms or other humid environments.

Lexaurin is supplied as an oral tablet and should be swallowed whole with a glass of water. It is taken by mouth as directed by the prescriber, typically with or without food, and should not be crushed or chewed unless specifically advised.

The most serious risks include respiratory depression, especially when combined with other central nervous system depressants, severe allergic reactions, and the potential for dependence, tolerance and withdrawal symptoms after prolonged use. Patients should be monitored closely for these events.

Lexaurin is contraindicated in patients with acute narrow‑angle glaucoma, severe respiratory insufficiency, severe hepatic impairment, or a known hypersensitivity to bromazepam or any benzodiazepine component. It should also be avoided in individuals with a history of substance misuse unless closely supervised.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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