Product image of Librachrom (Sodium Cromoglicate) supplied by GNH India

Librachrom

Active Ingredient:
Sodium Cromoglicate
Origin:
EU

Librachrom (Sodium Cromoglicate)

Sodium cromoglicate, the active ingredient in Librachrom, is a mast cell stabilizer presented as an ophthalmic solution for ocular use. It is employed to manage allergic conjunctivitis and other mast cell‑mediated eye inflammation, and is indicated for patients with seasonal or perennial ocular allergy symptoms requiring topical therapy.

GNH India supplies Librachrom as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with a focus on quality assurance and regulatory compliance, and reliable logistics solutions for global distribution.

Manufacturer / TM Owner

Aspire Pharma Limited

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Indications & Clinical Uses

  • Librachrom, containing sodium cromoglicate, is used to treat ocular conditions driven by mast cell activation and allergic pathways.
  • Allergic conjunctivitis: reduces itching, redness, tearing and swelling associated with allergic eye disease.
  • Mast cell‑mediated ocular inflammation: stabilizes ocular mast cells to prevent release of histamine and inflammatory mediators.
  • Seasonal allergic eye disease: provides relief of symptoms during pollen or allergen exposure periods.

How It Works

  • Sodium cromoglicate binds to calcium channels on mast cells, inhibiting calcium influx that is required for degranulation. By preventing mast cell activation, the drug blocks the release of histamine, prostaglandins, leukotrienes and other inflammatory mediators in the conjunctival tissue, thereby reducing allergic and inflammatory responses in the eye. The effect is localized to the ocular surface, with minimal systemic absorption, allowing targeted therapy without significant systemic exposure.

Side Effects

Adverse ocular reactions have been reported with topical sodium cromoglicate, although most are mild and transient.

Common Side Effects

  • Transient burning or stinging sensation upon instillation.
  • Temporary blurred vision.
  • Mild conjunctival redness.

Serious or Rare Side Effects

  • Allergic contact dermatitis of the eyelid or peri‑ocular skin.
  • Severe ocular inflammation or keratitis.
  • Corneal ulceration or vision loss.

Precautions & Warnings

  • When using Librachrom, certain precautions should be observed to ensure safety and optimal therapeutic outcome.
  • Pregnancy: consult a healthcare professional before use.
  • Breastfeeding: discuss potential risks with a physician.
  • Concurrent ocular infection: avoid use until infection is resolved.
  • Contact lens wearers: remove lenses before instillation and wait several minutes before reinserting.
  • Use with other ocular medications: space dosing by at least five minutes to prevent dilution.
  • Store at ambient temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Librachrom may interact with other ophthalmic agents; awareness of potential interactions helps maintain efficacy and safety.

Major Interactions (Avoid)

  • Concurrent use of topical ocular anesthetics: may increase corneal toxicity.
  • Combination with other mast cell stabilizers: no added therapeutic benefit.

Moderate Interactions (Monitor Closely)

  • Use with corticosteroid eye drops: monitor intraocular pressure.
  • Use with non‑steroidal anti‑inflammatory eye drops: observe for increased irritation.
  • Use with contact lens solutions: ensure compatibility to avoid lens damage.

Frequently Asked Questions

Librachrom is an ophthalmic preparation that contains sodium cromoglicate, a mast cell stabilizer. It is indicated for the treatment of allergic conjunctivitis and other mast cell‑mediated ocular inflammatory conditions, helping to relieve itching, redness, tearing and swelling of the eye.

Sodium cromoglicate stabilizes mast cells by blocking calcium influx required for degranulation. This prevents the release of histamine, prostaglandins, leukotrienes and other inflammatory mediators from conjunctival mast cells, thereby reducing the allergic and inflammatory response in the eye.

The dosing regimen for Librachrom is determined by the prescribing clinician based on the severity of the condition and patient factors. The prescriber will specify the number of drops, frequency and duration of therapy in the prescription.

Safety data for sodium cromoglicate in pregnancy and lactation are limited. Healthcare professionals should evaluate the potential benefits against any possible risks, and women who are pregnant or breastfeeding should discuss use with their physician before starting treatment.

To order Librachrom, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Librachrom (sodium cromoglicate) differs from antihistamine eye drops in that it stabilizes mast cells rather than blocking histamine receptors. This mechanism can provide broader control of inflammatory mediators, whereas antihistamines mainly relieve itching. Choice of therapy depends on clinical response, tolerance and physician preference.

Librachrom should be stored at ambient temperature, preferably below 25 °C, in its original container. Keep the bottle tightly closed, protect it from direct sunlight and moisture, and avoid freezing. Do not use the product after the expiry date printed on the label.

Librachrom is applied topically to the eye as directed by the prescriber. Typically, one or more drops are placed into the affected eye(s) using a clean fingertip to lower the bottle, avoiding contact with the ocular surface. Patients should wash their hands before and after administration.

Although rare, serious adverse events may include allergic contact dermatitis of the eyelid or peri‑ocular skin, severe ocular inflammation such as keratitis, corneal ulceration, or vision loss. Any sudden worsening of eye symptoms or signs of an allergic reaction should prompt immediate medical evaluation.

Librachrom should be avoided in individuals with known hypersensitivity to sodium cromoglicate or any excipients in the formulation. Patients with active ocular infections should defer use until the infection is resolved, and those wearing contact lenses should remove lenses before instillation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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