Product image of Libracor (Bisoprolol Fumarate) supplied by GNH India

Libracor

Active Ingredient:
Bisoprolol Fumarate
Origin:
EU

Libracor (Bisoprolol Fumarate)

Bisoprolol fumarate, the active ingredient in Libracor, is a beta blocker presented as an oral tablet for oral use. It is employed to manage high blood pressure, chronic heart failure, and angina pectoris in adult patients.

GNH India supplies Libracor as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Merck Ab

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Indications & Clinical Uses

Libracor is a selective β1‑adrenergic blocker used in cardiovascular disease management.

  • Hypertension: lowers systemic blood pressure and reduces cardiovascular risk.
  • Chronic heart failure: improves left‑ventricular function and decreases mortality.
  • Angina pectoris: reduces myocardial oxygen demand and relieves chest pain.

How It Works

  • Bisoprolol fumarate selectively antagonises β1‑adrenergic receptors in cardiac tissue, decreasing heart rate, myocardial contractility, and renin release. This results in reduced cardiac output and lowered arterial pressure, helping to control hypertension and lessen the workload on a failing heart.

Side Effects

Libracor may cause a range of adverse reactions.

Common Side Effects

  • Fatigue: feeling unusually tired or weak.
  • Dizziness: light‑headed sensation, especially on standing.
  • Headache: mild to moderate pain in the head.
  • Bradycardia: slower than normal heart rate.
  • Cold extremities: reduced blood flow to hands and feet.
  • Gastrointestinal upset: nausea or abdominal discomfort.

Serious or Rare Side Effects

  • Severe bradycardia: dangerously low heart rate requiring medical attention.
  • Heart block: impaired electrical conduction in the heart.
  • Hypotension: markedly low blood pressure causing faintness.
  • Bronchospasm: narrowing of airways, especially in asthmatic patients.
  • Allergic reactions: rash, itching, or swelling.
  • Depression: mood changes or depressive symptoms.

Precautions & Warnings

Before prescribing Libracor, clinicians should consider several safety factors.

  • Dose adjustment in renal impairment: reduce dose as needed based on renal function.
  • Monitor heart rate: avoid use if resting heart rate is below 60 bpm.
  • Caution in asthma or COPD: may exacerbate bronchospasm.
  • Avoid abrupt discontinuation: taper gradually to prevent rebound hypertension.
  • Use with caution in diabetes: may mask hypoglycaemia symptoms.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Libracor can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Other beta‑blockers: additive negative‑chronotropic effects.
  • Non‑dihydropyridine calcium channel blockers (verapamil, diltiazem): risk of severe bradycardia.
  • Certain antiarrhythmics (e.g., amiodarone): increased risk of heart block.

Moderate Interactions (Monitor Closely)

  • Diuretics: may potentiate hypotensive effects.
  • ACE inhibitors or ARBs: enhanced blood pressure lowering.
  • NSAIDs: may reduce antihypertensive efficacy.
  • Antidiabetic agents: possible masking of hypoglycaemia.
  • Antidepressants (e.g., SSRIs): monitor for bradycardia.

Frequently Asked Questions

Libracor contains bisoprolol fumarate and is prescribed to treat hypertension, chronic heart failure, and angina pectoris. By lowering blood pressure and reducing the heart's workload, it helps prevent cardiovascular complications in adult patients.

Bisoprolol fumarate selectively blocks β1‑adrenergic receptors in the heart, decreasing heart rate, contractility, and renin release. This leads to reduced cardiac output and lower arterial pressure, which benefits conditions such as high blood pressure and heart failure.

The appropriate dose of Libracor is determined individually by a qualified prescriber based on the patient’s clinical condition, response, and any comorbidities. Dosage adjustments may be required for renal impairment or elderly patients.

The pregnancy category for bisoprolol fumarate is listed as unknown, and safety data are limited. It should only be used during pregnancy or lactation if the potential benefit justifies the potential risk, and under close medical supervision.

To order Libracor, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Libracor (bisoprolol) is a cardio‑selective β1‑blocker, offering a lower risk of bronchospasm compared with non‑selective agents. It is often preferred for patients with respiratory disease, whereas other beta blockers may provide additional vasodilatory benefits but carry higher pulmonary side‑effect potential.

Libracor tablets should be stored at ambient temperature, below 25 °C, in the original packaging to protect from moisture and light. Keep the container tightly closed and out of reach of children.

Libracor is taken orally, usually once daily, with or without food as directed by the prescriber. Swallow the tablet whole with a glass of water and follow the dosing schedule provided by the healthcare professional.

Serious risks include severe bradycardia, heart block, marked hypotension, bronchospasm in patients with asthma or COPD, and rare allergic reactions. Patients should seek immediate medical attention if they experience fainting, extreme fatigue, difficulty breathing, or swelling of the face or throat.

Libracor is contraindicated in patients with severe bradycardia, second‑ or third‑degree heart block, overt heart failure decompensation, or untreated severe asthma/COPD. It should also be avoided in individuals who are hypersensitive to bisoprolol or any excipients in the tablet.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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