Product image of Librium (Chlordiazepoxide Hydrochloride) supplied by GNH India

Librium

Active Ingredient:
Chlordiazepoxide Hydrochloride
Origin:
EU

Librium (Chlordiazepoxide Hydrochloride)

Chlordiazepoxide hydrochloride, the active ingredient in Librium, is a benzodiazepine presented as an oral formulation for oral use. It is prescribed for anxiety disorders and for managing alcohol withdrawal syndrome.
GNH India supplies Librium as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Viatris Healthcare Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Chlordiazepoxide, a benzodiazepine that enhances GABA‑mediated inhibition, is indicated for the following conditions:

  • Anxiety disorders: reduces excessive worry and tension.
  • Alcohol withdrawal syndrome: eases withdrawal symptoms and helps prevent seizures.
  • Preoperative anxiety: provides short‑term sedation before surgical procedures.

How It Works

  • Chlordiazepoxide acts as a positive allosteric modulator at the GABA‑A receptor complex. By binding to the benzodiazepine site, it increases the frequency of chloride channel opening in response to GABA, thereby enhancing inhibitory neurotransmission and producing anxiolytic, sedative, and anticonvulsant effects.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Drowsiness
  • Fatigue
  • Dizziness
  • Impaired coordination
  • Blurred vision
  • Memory impairment

Serious or Rare Side Effects

  • Respiratory depression
  • Severe hypotension
  • Paradoxical agitation or aggression
  • Suicidal thoughts or behavior
  • Allergic reactions including rash or angioedema
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis

Precautions & Warnings

Before initiating therapy, consider the following safety measures:

  • Dose adjustment in elderly: start with a lower dose due to increased sensitivity.
  • Avoid abrupt discontinuation: taper gradually to prevent withdrawal symptoms.
  • Use with caution in hepatic impairment: the drug is metabolised by the liver.
  • Avoid concomitant CNS depressants: risk of additive sedation and respiratory depression.
  • Pregnancy and lactation: consult a healthcare professional; limited safety data are available.
  • Store at ambient temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Chlordiazepoxide can interact with several other medicines. Review the following categories:

Major Interactions (Avoid)

  • Opioids: additive respiratory depression.
  • Barbiturates: increased central nervous system depression.
  • Alcohol: potentiates sedative effect.

Moderate Interactions (Monitor Closely)

  • Antidepressants (SSRIs): may increase sedation.
  • Antihistamines: enhanced drowsiness.
  • CYP3A4 inhibitors (e.g., ketoconazole): may raise plasma levels of chlordiazepoxide.

Frequently Asked Questions

Librium, whose active ingredient is chlordiazepoxide, is prescribed primarily to treat anxiety disorders and to manage symptoms of alcohol withdrawal syndrome. It may also be used short‑term to relieve pre‑operative anxiety before surgical procedures.

Chlordiazepoxide binds to the benzodiazepine site on the GABA‑A receptor complex, acting as a positive allosteric modulator. This increases the frequency of chloride channel opening when GABA binds, enhancing inhibitory neurotransmission and producing calming, sedative, and anticonvulsant effects.

The appropriate dose of Librium is determined by the prescribing clinician based on the individual’s condition, age, liver function, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for chlordiazepoxide in pregnancy and lactation are limited. Healthcare professionals generally recommend avoiding use unless the potential benefit outweighs the risk. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives with their doctor.

To request Librium, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will verify trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Librium (chlordiazepoxide) has a relatively long onset of action and a moderate half‑life compared with agents such as diazepam or lorazepam. It is often chosen for alcohol‑withdrawal management because of its smoother tapering profile, whereas other benzodiazepines may be preferred for rapid anxiolysis or short‑term sedation.

Librium should be stored at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and excessive heat. Keep the product out of reach of children and do not use if the packaging is damaged.

Librium is taken orally, usually as a tablet, with or without food as directed by a healthcare professional. The exact administration schedule—such as frequency and duration—will be individualized by the prescriber.

The most serious risks include respiratory depression, especially when combined with other CNS depressants, severe hypotension, paradoxical agitation, suicidal thoughts, and rare but severe allergic reactions such as Stevens‑Johnson syndrome. Immediate medical attention is required if any of these occur.

Librium is contraindicated in individuals with known hypersensitivity to chlordiazepoxide or other benzodiazepines, those with acute narrow‑angle glaucoma, and patients who are currently intoxicated with alcohol or other CNS depressants. Caution is also advised for patients with severe respiratory insufficiency or severe hepatic impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.